Gene Symbol: wnt3a Gene Name: wingless-type MMTV integration site family, member 3A Synonyms: Xwnt-3a, xwnt3a, wnt-3a Add Xenopus synonyms Gene Function: secreted growth factor/developmental regulator Interactants: wnt8a(29) , dkk1(19) , dvl2(17) , nog(15) , otx2(15) , chrd(14) , bmp4(13) View All

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		NCBI Nucleotide >XM_002939308|PREDICTED: Xenopus (Silurana) tropicalis protein Wnt-3a-like (LOC100488632), mRNA ATGGGCTGCTTTGGATATTTCCTTATCATTTGCGGGCTGCACCAAGTCGCGGCGACTTATCCGATCTGGTGGTCATTAGCTGTCGGGCAACAATACTCCACTCTGGGGACCCAGCCCATTCCCTGCGGGACCATCCCGGGCCTGGTGGCCAAGCAGATGCGCTTCTGCAGGAATTACATGGAGATCATGCCCAGCGTGGCGGAAGGGGTTAAAATCGGCATTCAGGAGTGCCAGCACCAGTTCCGAGGGAGGAGGTGGAACTGCACGACCGTTAACGACAACCTGGCTATATTTGGACCGGTGTTGGATAAAGAGAAAAAGGAAATCGGTTTTAAAATTCTGAATTATTCGATCTTAGATCACAGACATCTTAAATGCAAATGTCACGGATTATCCGGAAGCTGTGAAGTGAAAACCTGCTGGTGGTCCCAGCCAGACTTCAGGGTGATCGGCGACTATCTCAAGGATAAATACGACAGCGCCTCCGAAATGGTGGTGGAGAAACATCGAGAATCCCGGGGATGGGTGGAAACCCTGAGGCCCAAATATACGTTCTTTAAGCCGCCTACAGAGAGAGATTTGATTTACTATGAGAGCTCCCCCAATTTCTGTGAGCCCAATCCCGAAACCGGATCCTTCGGAACCCGCGATCGGGTGTGCAACGTAACCTCCCATGGAATAGACGGCTGCGATCTTTTATGTTGCGGCCGAGGACACAACACAAGGACTGAGAAACGGAAAGAAAAATGTCACTGCATCTTCCATTGGTGTTGCTACGTCAGCTGTCAAGAATGTATAAGGGTATACGATGTTCATACATGTAAATAAGCATCTATTCCTAAACCGGGCTCTAGACATGAATCACGGGCCGGTTTGTCAAGCACCAGTAAGACTTTGACTGGTCGAATGGCGTAGGTGTTAAAGCTTCTTGGAAAGACTCAATGCACCTGGAGATTTAGACCTACTCAAATATGATCTTCACACACACAATACACAGTATATCCATGTTATTTTGCAATGGCATGAAGTGAAACGCAAGATAACCCCAAACTTCAGTGGTTCAGAAGATGCAACAACAACAGATAATCTACAAATATCACATTCCAAATACGTAACTGATGTTCTTGAGATGTTCTCAGTCGATGAGGAGTTTGTGCAAACTCAGTTGGATATTTAACTTTTCATTAA	Refseq >NM_001085874|Xenopus laevis wingless-type MMTV integration site family, member 3A (wnt3a), mRNA GAATTCCGGTGAACTCCCTGAGCTTCTTTATAAGGAGAGACAAAGTCTACCTGCTGGGGCTCAGCTCCCTCCTCTACTCTCAGCTCATATTTTATTTATATATCAATGGTTTTATTTTTTGTGATTTCTTTTTAAATATTATTTTTCACCTCTTTAATGATTTTTTTTTTACAAACACAAGGGATCGCTGGGAAACTGAATCCGCCGAATATTTAATCGATTATTTTTTGTTCTGTATTTTTTATATTATTGTTGTTATTATTATTATTATTATTTTTGATTCATTTTGGAGATGGGCTGCTTTGGATATTTGCTCCTCATCATTGGGCTGCACCAAGTCCTGGCTACTTACCCAATCTGGTGGTCATTAGCAGTCGGACAACAATACTCTTCTTTGGGGACCCAACCAATTCCCTGTGGTACAATTCCAGGGCTGGTGGCAAAGCAGATGCGCTTCTGCAGGAATTATATGGAGATTATGCCGAGCGTAGCAGAGGGTGTTAAAATCGGGATACAGGAGTGTCAGCACCAGTTCCGAGGGAGAAGGTGGAACTGCACCACAGTTAATGATAATCTGGCGATTTTTGGACCAGTGTTGGATAAAGCCACAAGAGAGTCAGCCTTTGTTCATGCCATAGCCTCGGCTGGAGTTGCATTTGCCGTAACCAGGTCTTGCGCTGAGGGATCTGCTACCATCTGCGGCTGTGATACCCATCACAAAGGACCTCCTGGGGAAGGCTGGAAGTGGGGAGGCTGCAGTGAAGATATGGATTTTGGAAGCATGGTGTCTCGAGAATTTGCAGATGCACGAGAGAACAGGCCAGATGCCCGATCAGCGATGAACAGGCACAACAATGAAGCAGGCAGAACATCGATCTTAGATCACAGGCATCTTAAATGCAAATGTCATGGATTGTCTGGAAGCTGCGAAGTTAAAACATGCTGGTGGTCCCAGCCAGACTTCAGGGTGATCGGCGACTATCTTAAGGATAAATACGACAGCGCTTCTGAAATGGTGGTGGAGAAACATCGAGAATCCCGGGGATGGGTTGAAACCCTGAGACCCAAATACACATTCTTTAAGCCTCCTATAGAGAGAGATTTGATTTACTATGAGAGCTCCCCCAATTTTTGTGAGCCCAATCCAGAAACTGGATCTTTTGGAACCCGCGATAGGGAATGCAATGTAACATCCCATGGAATAGATGGATGTGATCTTTTGTGTTGTGGTCGAGGACAAAACACAAGGACTGAGAAAAGGAAAGAAAAATGTCACTGCATTTTCCACTGGTGTTGCTACGTCAGCTGTCAAGAATGTATGAGGGTATATGACGTTCACACCTGCAAGTAAGCATCTAATCCTAAACCAGGCTCCATCTTAAAACATGACTCAAGGCCTGGTTTATCCGGCATGGATCGGTAAGACTTTGACTTTTGACTGGTCGATTAATGTAGGTGTAAAGGCTTCTTCCAAAGGCTCGATGCACCTGAGATTTAGACCTACTAAATATAATCTTCCCAAACGATACACAGTATATCCCCGTCATTTTGCAGTTCTTGTCATGTGTGTGATGACATGAAGTGAAATGCAAGAAACTTCAGAGTTCAGTGGTACAATATGTAAGAGAAGATGTGATTATGCAACGTCAGCAAGTAATCATCCATTATCACATTCCAAATATGTCATTGAGCAGTTCTCACTGTTTTGTGACTGACAAAGAGTGGTTGAGNAGTTTGTGCAACCTNCAGTTGGATATTTAATTTTTCATTAAGCAAAAAAGCGGAATTC
Protein		NCBI Protein >XP_002939354|PREDICTED: protein Wnt-3a-like [Xenopus (Silurana) tropicalis] MGCFGYFLIICGLHQVAATYPIWWSLAVGQQYSTLGTQPIPCGTIPGLVAKQMRFCRNYMEIMPSVAEGVKIGIQECQHQFRGRRWNCTTVNDNLAIFGPVLDKEKKEIGFKILNYSILDHRHLKCKCHGLSGSCEVKTCWWSQPDFRVIGDYLKDKYDSASEMVVEKHRESRGWVETLRPKYTFFKPPTERDLIYYESSPNFCEPNPETGSFGTRDRVCNVTSHGIDGCDLLCCGRGHNTRTEKRKEKCHCIFHWCCYVSCQECIRVYDVHTCK	Refseq >NP_001079343|protein Wnt-3a precursor [Xenopus laevis] MGCFGYLLLIIGLHQVLATYPIWWSLAVGQQYSSLGTQPIPCGTIPGLVAKQMRFCRNYMEIMPSVAEGVKIGIQECQHQFRGRRWNCTTVNDNLAIFGPVLDKATRESAFVHAIASAGVAFAVTRSCAEGSATICGCDTHHKGPPGEGWKWGGCSEDMDFGSMVSREFADARENRPDARSAMNRHNNEAGRTSILDHRHLKCKCHGLSGSCEVKTCWWSQPDFRVIGDYLKDKYDSASEMVVEKHRESRGWVETLRPKYTFFKPPIERDLIYYESSPNFCEPNPETGSFGTRDRECNVTSHGIDGCDLLCCGRGQNTRTEKRKEKCHCIFHWCCYVSCQECMRVYDVHTCK UniProtKB

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase
Synteny		Metazome

Expression		tropicalis	laevis
UniGene			Xl.880
Unigene EST Profile			EST Profile
GEO data			GEO
Images		15 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	WNT3A
mouse		MGI	Wnt3a	All(8) Targeted, knock Out(3) Targeted, other(2) Spontaneous(1) Chemically Induced(1)
zebrafish		ZFIN	wnt3a	3 Lines(s)

Publications
First:		Overlapping expression of Xwnt-3A and Xwnt-1 in neural tissue of Xenopus laevis embryos. [Dev Biol 1993]
Most recent:		The dual regulator Sufu integrates Hedgehog and Wnt signals in the early Xenopus embryo. [Dev Biol 2013]
		View All Papers 24 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		signal transducer activity
Biological:		Wnt receptor signaling pathway, calcium modulating pathway multicellular organismal development
Cellular Component:		extracellular region
EC:
KOG:		[T] Wnt family of developmental regulators

Reagents		tropicalis	laevis
Clones			EXRC - 1 clone(s)
			open biosystems
			geneservice/RZPD imagenes
Affymetrix 1.0			Xl.880.1.S1_at
Affymetrix 2.0			Xl2.880.1.S1_at

Symbol legend[+]

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