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Summary Expression Gene Literature (144) GO Terms (16) Nucleotides (184) Proteins (35) Interactants (744) Wiki
XB-GENEPAGE-1217555

Gene Symbol: mapk8

Gene Name: mitogen-activated protein kinase 8

Synonyms: jnk , jnk1 , sapk1 , xJNK ( Add Xenopus synonyms , Nomenclature history )

Gene Function: serine-threonine protein kinase

Protein Function :
Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulating transcriptional activity. Regulates morphogenic c...[+]

Interactants: Loading ...
Disease Ontology:

OMIM Diseases:

 
Xenbase Gene ID XB-GENE-1217556 XB-GENE-1217560 XB-GENE-17339765
Gene Symbol mapk8 mapk8.L mapk8.S
Chromosome Chr07 Scaffold27067 Scaffold231013
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq NCBI Nucleotide
Protein Refseq TrEMBL TrEMBL TrEMBL Refseq Swiss-Prot TrEMBL Swiss-Prot NCBI Protein TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression
Data Mining tropicalis laevis.L laevis.S
XenMine mapk8 mapk8.L mapk8.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards MAPK8 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Mapk8 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR ZFIN, AGR mapk8a mapk8b ZFIN Ensembl
chicken
GEISHA MAPK8 Ensembl
fruit fly
worm
WORMBASE
Publications
First Activation of mitogen-activated protein kinase cascades by p21-activated protein kinases in cell-free extracts of Xenopus oocytes., J Biol Chem 1995  
Most Recent Peroxiredoxin5 Controls Vertebrate Ciliogenesis by Modulating Mitochondrial Reactive Oxygen Species., Antioxid Redox Signal 2019    
All View All Papers 31 paper(s) referencing morpholinos 1 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 14 terms 6 terms 0 term
PANTHER mapk8
KEGG Pathways K04440 K04440
KOG [T] Jun-N-terminal kinase (JNK)
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Dharmacon Dharmacon Dharmacon
Antibody Mapk8 Ab1 , Mapk8 Ab2 , mapk8 Ab3 Mapk8 Ab1 , Mapk8 Ab2 , mapk8 Ab3 mapk8 Ab3
Morpholino mapk8 MO1 , mapk8 MO2 mapk8 MO1 , mapk8 MO2 mapk8 MO1 , mapk8 MO2
ORF mapk8.L ORF1
Affymetrix 1.0 StrEns.8093.1.S1_at Xl.8740.1.S1_at Xl.23521.1.S1_at
Affymetrix 2.0 Xl2.8740.1.S1_at Xl2.23521.1.S1_at [+]

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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