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Summary Expression Gene Literature (18) GO Terms (17) Nucleotides (293) Proteins (69) Interactants (298) Wiki
XB-GENEPAGE-1217591
Gene Symbol:
pbx1

Gene Name:
pre-B-cell leukemia homeobox 1

Synonyms:
Xpbx1 , Xpbx1b , pbx1b ( Add synonyms , Nomenclature history )

Gene Function:
homeodomain transcription factor

Protein Function :
Acts as a transcriptional activator in complex with isoform 2 of meis1, to induce posterior neural and neural crest gene expression, and thereby specify hindbrain and neural crest cell fate. Binds to a...[+]



Interactants:
Loading ...

Diseases: 


OMIM:
CONGENITAL ANOMALIES OF KIDNEY AND URINARY TRACT SYNDROME WITH OR WITHOUT HEARIN

External Links:
 
Xenbase Gene ID XB-GENE-1217592 XB-GENE-17346770 XB-GENE-1217596
Gene Symbol pbx1 pbx1.L pbx1.S
Chromosome Chr04 chr4L chr4S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100216094
108714419
399184
mRNA RefSeq NCBI Nucleotide RefSeq
Protein RefSeq Swiss-Prot NCBI Protein RefSeq
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine pbx1 pbx1.L pbx1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards PBX1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Pbx1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Pbx1 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR pbx1a pbx1b ZFIN Ensembl
chicken
GEISHA PBX1 Ensembl
fruit fly
worm
Publications
First The hexapeptide LFPWMR in Hoxb-8 is required for cooperative DNA binding with Pbx1 and Pbx2 proteins., Proc Natl Acad Sci U S A 1995  
Most Recent Endodermal Maternal Transcription Factors Establish Super-Enhancers during Zygotic Genome Activation., Cell Rep 2019                            
All View All Papers 4 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 13 terms 3 terms 12 terms
PANTHER pbx1
KEGG Pathways K09355 K09355 K09355
KOG [K] Transcription factor PBX and related HOX domain proteins
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks pbx1
Antibodies Pbx1 Ab1 Pbx1 Ab1
Morpholinos pbx1 MO1 pbx1 MO1 pbx1 MO1
ORFs pbx1.S ORF1
Clones Horizon Source BioScience Horizon Horizon

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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