Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (45) GO Terms (14) Nucleotides (108) Proteins (31) Interactants (73) Wiki
XB-GENEPAGE-1217707
Gene Symbol:
wdhd1

Gene Name:
WD repeat and HMG-box DNA binding protein 1

Synonyms:
and-1 , ctf4 , and1 ( Add synonyms , Nomenclature history )

Gene Function:
WD40 repeat protein

Protein Function :
Acts as a replication initiation factor that brings together the MCM2-7 helicase and the DNA polymerase alpha/primase complex in order to initiate DNA replication.



Interactants:
Loading ...

Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-1217708 XB-GENE-1217712 XB-GENE-17340346
Gene Symbol wdhd1 wdhd1.L wdhd1.S
Chromosome Chr8 chr8L
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1
CDS Gene model Gene model
Entrez Gene 100493060
397870
mRNA NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein NCBI Protein RefSeq  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine wdhd1 wdhd1.L wdhd1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards WDHD1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Wdhd1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Wdhd1 Ensembl
zebrafish
ZFIN, AGR wdhd1 ZFIN Ensembl
chicken
GEISHA WDHD1 Ensembl
fruit fly
worm
Publications
First AND-1, a natural chimeric DNA-binding protein, combines an HMG-box with regulatory WD-repeats., J Cell Sci 1997  
Most Recent Claspin - checkpoint adaptor and DNA replication factor., FEBS J 2019  
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 12 terms 4 terms 0 term
PANTHER wdhd1
KEGG Pathways K11274
KOG [R] WD40 repeat protein (alt_id KOG:1274)
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks wdhd1
ORFs wdhd1.L ORF1
Clones Horizon Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list