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XB-GENEPAGE-1218922
Gene Symbol:
nlk.2
Gene Name: nemo-like kinase, gene 2
Synonyms:
xnlk
( Gene Function: serine/threonine kinase Protein Function
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Negatively regulates Wnt/beta-catenin-signaling during development. Plays a role together with sox11 in neural induction during early embryogenesis. Involved in TGFbeta-mediated mesoderm induction in e...[+]
Interactants:
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Diseases: External Links:
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Xenbase Gene ID | XB-GENE-1218923 | XB-GENE-17333536 | XB-GENE-1218927 | |||||
Gene Symbol | nlk.2 | nlk.2.L | nlk.2.S | Chromosome | Chr9 | Scaffold22 | Scaffold29 | |
Molecules | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genomic Sequence |
Version 10.0
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Version 9.1
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Version 9.1
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CDS |
Gene model
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Gene model
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Gene model
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Entrez Gene |
100144684
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108703801
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398295
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mRNA |
NCBI Nucleotide
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NCBI Nucleotide
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NCBI Nucleotide
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Protein
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Genomic |
X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genome Browser (Click image to open in Genome Browser) |
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Genomic Synteny | Genomicus PANTHER | |||||||
Expression | Development Stages | Embryonic Tissues | Adult Tissues | |||||
Summary for |
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More Information |
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Proteomics | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Embryonic Protein Expression | Stage profile:![]() |
Stage profile:![]() |
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Data Mining | X. tropicalis | X. laevis.L | X. laevis.S | |||||
XenMine | nlk.2 | nlk.2.L | nlk.2.S | |||||
Orthology |
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human |
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mouse |
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rat |
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zebrafish |
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chicken |
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fruit fly |
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worm |
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Publications | ||||||||
First |
The TAK1-NLK-MAPK-related pathway antagonizes signalling between beta-catenin and transcription factor TCF., Nature 1999 |
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Most Recent |
Nemo-like kinase, an essential effector of anterior formation, functions downstream of p38 mitogen-activated protein kinase., Mol Cell Biol 2010 ![]() |
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All | View All Papers 2 paper(s) referencing morpholinos | |||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||
GO | 43 terms | 0 term | 20 terms | |||||
PANTHER | nlk.2 | |||||||
KEGG Pathways | K04468 [+] | K04468 | ||||||
KOG |
[T] Nemo-like MAPK-related serine/threonine protein kinase
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Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||
CRISPRscan Tracks | nlk.2 | |||||||
Morpholinos | nlk.2 MO1 | nlk.2 MO1 | nlk.2 MO1 | |||||
ORFs | nlk.2.S ORF1 | |||||||
Clones | Horizon Source BioScience | Horizon | Horizon Source BioScience | |||||
Plasmids | Addgene | Addgene |
Symbol legend:



