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Summary Expression Gene Literature (8) GO Terms (21) Nucleotides (90) Proteins (27) Interactants (44) Wiki
XB-GENEPAGE-1218968
Gene Symbol:
lin28b

Gene Name:
lin-28 homolog B

Synonyms:
LIN-28 ( Add synonyms , Nomenclature history )

Gene Function:
RNA binding

Protein Function :
Suppressor of specific microRNA (miRNA) biogenesis. Binds target primary miRNA transcripts and sequester them in the nucleolus, away from the microprocessor complex, hence preventing their processing i...[+]



Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-1218969 XB-GENE-17334719 XB-GENE-1218973
Gene Symbol lin28b lin28b.L lin28b.S
Chromosome Chr05 chr5L chr5S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100216028
108716855
373796
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein RefSeq NCBI Protein NCBI Protein
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine lin28b lin28b.L lin28b.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards LIN28B OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Lin28b MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Lin28b Ensembl
zebrafish
ZFIN, AGR lin28b ZFIN Ensembl
chicken
GEISHA LIN28B Ensembl
fruit fly
worm
Publications
First Conservation of the heterochronic regulator Lin-28, its developmental expression and microRNA complementary sites., Dev Biol 2003          
Most Recent LIN28B increases neural crest cell migration and leads to transformation of trunk sympathoadrenal precursors., Cell Death Differ 2020  
All View All Papers 1 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 16 terms 4 terms 9 terms
PANTHER lin28b
KEGG Pathways K18754
KOG [J] Predicted RNA-binding protein containing PIN domain and invovled in translation or RNA processing
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks lin28b
Morpholinos lin28b MO1 lin28b MO1 lin28b MO1
Clones Horizon Source BioScience Horizon Horizon Source BioScience

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