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Summary Expression Gene Literature (1) GO Terms (6) Nucleotides (70) Proteins (28) Interactants (83) Wiki
XB-GENEPAGE-1219056
Gene Symbol:
zfyve28

Gene Name:
zinc finger FYVE-type containing 28

Synonyms:
lst2 ( Add synonyms , Nomenclature history )

Gene Function:
FYVE finger-containing protein

Protein Function :
Negative regulator of epidermal growth factor receptor (EGFR) signaling. Acts by promoting EGFR degradation in endosomes when not monoubiquitinated.


InterPro :
Znf FYVE , Znf RING/FYVE/PHD , Znf FYVE-rel , Znf FYVE PHD [+]

Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-1219057 XB-GENE-1219059 XB-GENE-17337281
Gene Symbol zfyve28 zfyve28.L zfyve28.S
Chromosome Chr1 chr3L
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.2
CDS Gene model Gene model
Entrez Gene 779953
447053
mRNA RefSeq NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine zfyve28 zfyve28.L zfyve28.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards ZFYVE28 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Zfyve28 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Zfyve28 Ensembl
zebrafish
ZFIN, AGR zfyve28 ZFIN Ensembl
chicken
GEISHA ZFYVE28 Ensembl
fruit fly
worm
Publications
First Asymmetric distribution of biomolecules of maternal origin in the Xenopus laevis egg and their impact on the developmental plan., Sci Rep 2018                  
Most Recent
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 6 terms 1 terms 0 term
PANTHER zfyve28
KEGG Pathways
KOG [R] FYVE finger-containing proteins
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks zfyve28
ORFs zfyve28.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info