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Summary Expression Gene Literature (4) GO Terms (19) Nucleotides (1367) Proteins (47) Interactants (236) Wiki
Gene Symbol:

Gene Name:
DEAD-box helicase 21

xGu-1 ( Add synonyms , Nomenclature history )

Gene Function:
ATP-dependent RNhelicase

Protein Function :
RNA helicase that acts as a sensor of the transcriptional status of both RNA polymerase (Pol) I and II: promotes ribosomal RNA (rRNA) processing and transcription from polymerase II (Pol II). Binds var...[+]

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External Links:
Xenbase Gene ID XB-GENE-1012547 XB-GENE-1012552 XB-GENE-17331446
Gene Symbol ddx21 ddx21.L ddx21.S
Chromosome Chr07 Scaffold124 chr7S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 734085
mRNA RefSeq RefSeq RefSeq
Protein RefSeq RefSeq Swiss-Prot Swiss-Prot RefSeq Swiss-Prot Swiss-Prot
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine ddx21 ddx21.L ddx21.S
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
HGNC AGR, OMIM:Gene, GeneCards DDX21 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
MGI, AGR Ddx21 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
RGD, AGR Ddx21 Ensembl
ZFIN, AGR ddx21 ZFIN Ensembl
GEISHA DDX21 Ensembl
fruit fly
First Down-regulation of RNA helicase II/Gu results in the depletion of 18 and 28 S rRNAs in Xenopus oocyte., J Biol Chem 2003  
Most Recent Tissue-selective effects of nucleolar stress and rDNA damage in developmental disorders., Nature 2018  
All View All Papers 1 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 10 terms 12 terms 12 terms
KEGG Pathways K16911 K16911 K16911
KOG [A] ATP-dependent RNhelicase (alt_id KOG:0331)
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks ddx21
Morpholinos ddx21 MO1 ddx21 MO1 ddx21 MO1
ORFs ddx21.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon

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