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Summary Expression Gene Literature (10) GO Terms (14) Nucleotides (47) Proteins (20) Interactants (603) Wiki
XB-GENEPAGE-994473
Gene Symbol:
rspo3

Gene Name:
R-spondin 3

Synonyms:
( Add synonyms , Nomenclature history )

Gene Function:
subtilisin-like proprotein convertase; regulates the balance between angioblast and blood cell specification

Protein Function :


InterPro :
Leu-rich rpt , LRR dom sf , Leu-rich rpt typical-subtyp , TSP1 rpt [+]

Interactants:
Loading ...

Diseases: 


External Links:
1/3
 
Xenbase Gene ID XB-GENE-994474 XB-GENE-17340703 XB-GENE-17340704
Gene Symbol rspo3 rspo3.L rspo3.S
Chromosome Chr5 chr5L
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1
CDS Gene model Gene model
Entrez Gene 496565
108716762
mRNA NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine rspo3 rspo3.L rspo3.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards RSPO3 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Rspo3 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Rspo3 Ensembl
zebrafish
ZFIN, AGR rspo3 ZFIN Ensembl
chicken
GEISHA RSPO3 Ensembl
fruit fly
Publications
First R-Spondin2 is a secreted activator of Wnt/beta-catenin signaling and is required for Xenopus myogenesis., Dev Cell 2004                            
Most Recent RSPO2 inhibition of RNF43 and ZNRF3 governs limb development independently of LGR4/5/6., Nature 2018    
All View All Papers 4 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 14 terms 3 terms 0 term
PANTHER rspo3
KEGG Pathways K23098 K23098
KOG [O] Subtilisin-like proprotein convertase
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks rspo3
Morpholinos rspo3 MO1 rspo3 MO1
Clones Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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