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Summary Expression Gene Literature (26) GO Terms (8) Nucleotides (90) Proteins (17) Interactants (179) Wiki
XB-GENEPAGE-22066184
Gene Symbol:
h2ax

Gene Name:
H2A.X variant histone

Synonyms:
h2afx , XH2AX ( Add synonyms , Nomenclature history )

Gene Function:


Protein Function :
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA...[+]


Interactants:
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Diseases: 


External Links:
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Xenbase Gene ID XB-GENE-22066185 XB-GENE-17331790 XB-GENE-5719408
Gene Symbol h2ax h2ax.L h2ax.S
Chromosome Chr07 chr7L Scaffold80
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100487455
108696445
444528
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein NCBI Protein Swiss-Prot
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine h2ax h2ax.L h2ax.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
H2AX Ensembl, Allen Brain Atlas, Protein Atlas
mouse
H2ax Ensembl
rat
RGD, AGR H2ax Ensembl
zebrafish
ZFIN, AGR h2ax ZFIN Ensembl
chicken
H2AFX Ensembl
fruit fly
worm
Publications
First Megabase chromatin domains involved in DNA double-strand breaks in vivo., J Cell Biol 1999                
Most Recent Kinesin Kif2C in regulation of DNA double strand break dynamics and repair., Elife 2020                                                          
All View All Papers 1 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 4 terms 4 terms 8 terms
PANTHER h2ax
KEGG Pathways K11251 K11251 K11251
KOG
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks h2ax
Clones Horizon Horizon Horizon Source BioScience

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