tbx1 Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (20)

Nucleotides (112)

Interactants (107)

XB-GENEPAGE-478083

Gene Symbol: tbx1 Gene Name: T-box 1 Synonyms: xtbx1, cafs, cthm, dgcr, dorv, vcfs, tbx1c Add Xenopus synonyms Gene Function: T-box transcription factor Interactants: fgf8(6) , tbx5(6) , myf5(3) , myh4(3) , nkx2-5(3) , t(3) , tbx2(3) View All	1/2

XB-GENE-478084

XB-GENE-6254396

XB-GENE-478088

Molecules		tropicalis	laevis a		laevis b
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene		Entrez Gene
mRNA		Refseq >NM_001035118\|Xenopus (Silurana) tropicalis T-box 1 (tbx1), mRNA AGGCACTTGGGTGTCAATCATCTGCTTAGAGCTGCTTAGAGTCTCCCAGGCGAGGAAGAGGCGAGTTACCTGCAGCTCTCGCTTATCCAAATCGCAGTAGGAACTGGTTGGTGGCAGGAGGGCGGGGGGGCTGCCTGCCTGAGCACGAAAGCAGCTAAGTCTCCTGCACAGACACAGCCGCAGCCTACAGAGGGGAAGGGAGCACAGACTGGGGCAGTACTCAGCGAGAGCGCAAAAGGCACACGGCAAGGACACAAAGGATCTATTTTATTCAATGGGAATGTTACCCACTTGCAGGCTACACCGGGCACTGCCAGCAGTACCAGCCAGTCCCTGCCTTGTCTAACCTACTCGCTGGGCTCAGCTTACTCCAGGGAGAGGGAGCAACAGGCAACTGAGCGCACAGCACTTTCCCCATTCTGCTGCCCCACAACCAAGGCTCGGGATCCCCGCACCTACCCAAACCCCCTGCCCCACGGACGGAGTGGAACAGCCACACATTAACCCTTTGTTTTCTCCCCCTCTTCCCTGTCTATTCCTGGGATGATCTCGGCCATCTCCAGCCCCTGGCTCACCCAGCTCTCCCATTTTTGCGATGTTGCAGCTTTCACGGCCAACAGCCTGAGCAGCCTGAACGCATCGGGGGGCTACCACCTCTCCCCTTCCCCAGGGGACCCCTACAGCCAACATGAGCCCCACTACGAGCCCTGCTCCGCCAGCCAGCACTCGTACAGCTTCGGCCATGCCTGCCCAGAGCCTGAGAGTGGAGCCTCCTCCTCAAGCTGCGCCTCCTCCACCCCGGGGAGCGGCAGCACTGGCAGCAGCGGCAGCAGCAAGGCCCCAGTGAAGAAGAACCCCAAGGTGGCCAACATCACCGTGCAGCTGGAGATGAAAGCTCTGTGGGACGAGTTCAACCAGCTGGGCACTGAAATGATAGTCACCAAGGCTGGCAGGCGTATGTTCCCCACCTTCCAGGTTAAGATTTTTGGGATGGATCCCATGGCTGATTACATGTTATTAATGGACTTTGTACCAGTGGACGATAAACGGTATCGGTACGCCTTTCACAGCTCCTCCTGGTTAGTGGCAGGCAAAGCAGACCCGGCCACCCCCGGCAGGGTTCACTATCACCCGGATTCTCCAGCCAAAGGGGCCCAGTGGATGAAGCAAATCGTGTCCTTTGACAAACTGAAACTGACTAATAACTTATTGGACGACAACGGCCATATCATCCTAAACTCCATGCACAGGTACCAGCCCCGCTTCCATGTGGTCTACGTGGATCCGAGGAAGGACAGCGAGAAGTACGCAGAGGAAAACTTTAAAACGTTTGTGTTCGAGGAGACGCGCTTTACTGCAGTGACGGCCTATCAGAACCACAGGATTACACAACTGAAAATTGCTAGTAATCCATTTGCCAAGGGATTCAGAGACTGTGACCCGGAAGACTGGCCCAGAAATCACAGGCCTGGATCCCTCCCTCTTATGAATGCCTTTGCAAGGTCTAGGAATCCTGTGTCATCACCCCCACAGAATGGAAGTGACAAAGATGGAGATGGAAGAAGAGAATATGAAAGAGATACTAGTGGTACACCTCTTCATGGGGATGCAGCACATCAACAGCTTATGTCCCGTGTCCTCAGCCCTTCCCTGCCTGTTCCTGGTGGACTTGTACCTCTCAGTACTGGGAGACCCAGCCCCCCACATGAACTGCGCCTAGACCCCCATTCTCAAGGCTCAGAACCACTGCACCATCACCCCTACAAGTACCCAACCAGCTACGATCATTACCTAGGAGCAAAAACCAGACCGGCCCCCTATCCTTTGCCAAGTATCAGAGGACATGGCTACCATCATCATCCTATGAACCCAGCAGCAGCAAATATGTACTCAGGAGCTGGTGCACCAGGCAGTTATGAATATGGGCCAAGATAACATCTTGGCAGGAGGCTATTCTTACTGAATGACTATTTAATTAATATGTAAGACAATGGATGTTTCATGCATGATTTTAATTATTCAGTAGTGTATGCTTTGGATGTTACATTACTGTTAAAATGAAAGCTGACCTCTCCCTTAAGTCACATGGACAGCCCTGCAGCTTTATCAGTAATTTGTGAAAGTCTTCATGCAAACAAGCTGGATCATCTAACAAATCCTGCTCGAGCTGTTCCGATATTACATCAGCAGAAAACAAGCAAAGGCACTTGAGTTCTTCGTCTTTTTTTTTTTTTTTCTTTTATTTGTTCAAATGCTAACTGGAAACAGAGGGCAGACACGTAGAAAAGGAGGTGTCCATGGACCTCTGTACATGCCCATGTCTCCTTCTGCGTGTGAGGGGGTTACCTCATCCCACCCGACCTCCAAAAATGCACTGTTCAATTACTAACTGATTCCAGTCCACCCACCAATGGGCATTGACTTTTATGGGGCCTGGTGCACTATTCATGCTTGTAAGAAGCCATATACTTTGTTTTGCTGTTGGTTTTATTTTCAATTACTGGAAAAAAATGTTGAGTTGCCTCAGGTGCAGAGGAACTCTGAGGCGATATAAGCAGTTTCAGTGTATGATCTCTGTGTGTATATATTATATATATATATTTGGTCATAAAGGGTTTGTTATCAACCTATAGCAACCCACTGGCACAGTATGGTATATGGACAATGAAAGTGCCACTCCTGTCCATTTACAGAAGTACATTGCTGCTTCTACCTTCCTCAGAGTGCCACCGTTGTTCCCATAATCCACCTGCTGAGCTCATACAAAATTTGTTCTTCCAAAACCATTTAACCATAACCCCTACTGACTGCATTAGTATGTAATGACTCACCAAGAAATGTGTGTTTTGTGACTCAAACAATTATAAATTTGCAGTGTATTTTCAAAATGTAAGTCTGTTTACCTCCCCTAGATTTTTTTCCAGTGACAAACCATAGGAAGTTGGGTGGAAGGAAGTTTCCCATGACATTGCAGAATAATCATTTATCAAAGGAATCCATCGAGGTTGGAATATGGTTCTCTAAGGGCAGAAATATATAAAGTGTTACCTGTTTCAGACACTAAC	Refseq >NM_001090445\|Xenopus laevis T-box 1 (tbx1-a), mRNA GCACTGCCACAGCAGCACTAGTCTGCCTTGCGTAACTTACTTACAGCTCGGCTCAACTTACTCCAGGAAAAGGGAGCAACAGAGAACTGAGCGCACAGTACCTTCCCCATTCTGCTGCCCCACAGCCAAGGCTCGGGATCCCCGCACTTTCCTTGCCCCACGGACAGAGTGAAACAGCAGCAGCACATTAACCCTTTGTTTTCTCCCCCCTCTTCCCTGTCTATTCCTGGGATGATCTCGGCCATCTCCAGCCCCTGGCTCACCCAGCTCTCCCATTTTTGCGATGTTGCAGCTTTCACGGCCAACAGCCTGAGCAGCCTGAACGCTACGGGGGGCTATCACCTCTCCCCTTCCCCGGGGGACCCGTACAGCCAGCACGAACCCCACTACGAACCCTGCTCCGCCAGCCAACACTCGTACAGCTTCGGCCATGCCTGCCCAGAGCCTGAGAGCGGAGCCTCGTCCTCCAGTTGCGCCTCCTCCACCCCGGGGAGCGGCAGTACAGGCAGCAGCAGCAGCAACAAGGCCCCAGTGAAGAAGAACCCCAAGGTGGCCAACATCAACGTGCAGCTGGAAATGAAAGCTCTGTGGGACGAGTTCAACCAGCTGGGCACTGAAATGATAGTCACCAAGGCTGGCAGGCGAATGTTCCCCACCTTCCAGGTTAAGATTTTTGGAATGGATCCCATGGCTGATTACATGTTATTAATGGACTTTGTACCAGTGGACGATAAACGGTATCGGTACGCGTTCCACAGCTCCTCCTGGCTAGTGGCAGGCAAAGCAGACCCGGCCACGCCCGGTAGGGTTCACTATCACCCGGATTCTCCAGCTAAAGGGGCTCAGTGGATGAAGCAGATCGTGTCTTTTGACAAACTGAAACTGACCAATAACTTATTGGACGACAACGGCCACATCATCCTGAACTCCATGCACAGGTACCAGCCCCGCTTCCATGTGGTGTATGTGGATCCGAGGAAGGACAGTGAGAAGTATGCAGAGGAGAACTTTAAAACGTTCGTGTTCGAGGAGACACGCTTTACCGCAGTGACGGCCTATCAGAACCACAGGATTACACAACTGAAAATTGCTAGCAATCCATTTGCTAAGGGATTCAGAGACTGCGACCCAGAAGACTGGCCTAGAAATCATAGACCTGGATCCCTCCCTCTTATGAATGCTTTTGCAAGGTCTCGAAATCCTGTCTCCTCCCCCACACAGAATGGAAGTGACAAAGATGGAGATGGCCGAAGAGAATATGAAAGAGATGCTAGTGGTACACCTCTGCATGGGGATGCAGCACATCAACAGCTTATGTCGCGAGTCCTCAGCCTTTCCCTGCCTGTTCCTGGTGGACTTGTACCTCTCAGTACTGGCAGACCCAGCCCCCCACATGAACTGCGCCTAGACCCCCACTCTCAAGGCTCCGAACCACTGCACCACCATCCTTACAAGTACCCAACCAGCTACGATCGTTACCTAGGAGCAAAAACCCGACCAGCCCCCTACCCTTTGCCAACTATCAGAGGACATGGCTATCATCATCACCATATGAACCCAGCAGCAGCAAATATGTACTCGGGAGCTGGTGCACCAGGCAGTTATGAATATGGGCCAAGATAACATCTGAAGCAGGAGGCTATACTTATTGAATGACTATTTAATACATATGTAAGACAATGGATGTTTCATGCATGGTTTTAATTATTCAGTAGTGTATGCTTTGGATATTACATTACTGTTAAAATGAAAGCTGACCTCTCCCTAAAGTCACATGGGCAGCCCTGCAGCTTTATCAGTAATTTGTGAAAATCTTTATGCAAACAAGCTGGATCATCTAACAAATCCTGCTCGAG		Refseq >NM_001096675\|Xenopus laevis T-box 1 (tbx1-b), mRNA AGGGAACTGAGCGCACCTTCCCCATTCTGCTGCCCCACAGCCACTGCTCGGGATCCCCGCACCTTCCCAACCCCTACCCCACGGACAGAGTGGAGCAGCAGCAGCACATTAACCCTTTGTTTTCTCCCCCCTCTTCCCTGTATATTCCTGGGATGATCTCGGCCATCTCCAGCCCCTGGCTCACCCAGCTCTCCCATTTTTGCGATGTTGCAGCTTTCACGGCGAACAGCCTGAGCAGCTTGAACGCTTCGGGGGGCTACCACCTCTCCCCTTCCCCGGGGGACCCGTACAGCCAGCACGAACCCCACTACGAACCCTGCTCCGCCAGCCAACACTCGTACAGCTTCGGCCATGCCTGCCCAGAGCCTGAGAGCGGAGCCTCGTCCTCTAGTTGCGCCTCCTCCACCCCGGGGAGCGGCAGTACAGGCAGCAGCAGCGGCAACAAGGCTCCGGTGAAGAAGAACCCCAAGGTGGCCAACATCACCGTGCAGCTGGAGATGAAAGCTCTGTGGGACGAGTTCAACCAGCTGGGCACTGAAATGATAGTCACCAAGGCTGGCAGGCGTATGTTCCCCACCTTCCAGGTTAAGATTTTTGGGATGGATCCCATGGCCGATTACATGTTATTAATGGACTTTGTACCAGTGGACGATAAACGGTATCGGTATGCCTTTCACAGCTCCTCGTGGTTAGTGGCAGGCAAAGCAGACCCGGCCACACCCGGTAGAGTTCACTATCACCCGGATTCTCCAGCCAAGGGGGCTCAGTGGATGAAGCAGATCGTGTCCTTTGACAAACTGAAACTGACAAATAACTTATTGGACGACAACGGGCACATCATCCTGAACTCCATGCACAGGTACCAGCCCCGCTTCCATGTGGTCTACGTGGATCCGAGGAAGGACAGCGAGAAGTACGCAGAGGAGAACTTTAAAACGTTCGTGTTCGAAGAGACGCGCTTTACGGCAGTGACGGCCTATCAGAACCACCGGATTACACAACTGAAAATTGCTAGCAATCCATTTGCCAAGGGATTCAGAGACTGTGACCCAGAAGACTGGCCCAGAAATCATAGACCTGGATCCCTCCCTCTTATGAATGCTTTTGCAAGGTCTAGGAATCCTGTCTCCTCCCCTCCACAGAATGGAAGTGATAAAGATGGAGATGGCCGAAGAGAATATGAAAGAGATGCTAGTGTTACACCTCTGCATGGGGATGCAGCACATCAACAGCTTATGTCACGAGTACTCAGCCCGTCCCTGCCTGTTCCTGGTGGACTTGTACCTCTCAGTACTGGCAGACCCAGCCCCCCACATGAACTGCGCCTAGACCCCCATTCTCAAGGCTCAGAACCACTGCACCACCATCCTTACAAGTACCCAACCAGCTACGATCATTACCTAGGAGCAAAAACCCGACCGGCCCCCTACCCTTTGCCAAGTATCAGAGGACATGGCTACCATCATCACCCTATGAACCCAGCAGCAGCAAATATGTACTCGGGAGCTGGTGCACCAGGCGGTTATGAATACGGGCCAAGATAACATCTGCAGCAGGAGCCTATACTTATTGAATGACTATTTAATAAATATATAAGACAATGGATGTTTCATGCATGATTTTAATTATTCAGTAGTGTATTGGATATTACATTACTGTTAAAATGAAAGCTGACCTCTCCCTAAAGTCACATGGGCAGCCCTGCAGCTTTATCAGTAATTTGTGAAAATCATCATGCAAACAAACTGGATCATCTAACAAATCCTGCTCGAGCTGTTCCGATATTACATCAGCAGAAAGCAAGCAAAGGCACTTGAGTTTGTCGTCTTTTTTCTTTTATTTGTTCAAATGCTAACTGGAAACAGAGGACAGACACGTTGAAGAGGAGGTGTCCAGGGACCTCTGTACATGCACATGTTTATTAAAGCTCCAAGTCTCCTTCTGCTTGTGGAGGAGATAGTTCATCCCACCCGACCTCCACAGATGCACTGTTCAATTACTAACTGACATCAGTCCACCCACCAAGGGCATTGACTTTTATGGGGCCTGGTGCACTAATAACGCTTGTAAGAAGCCATATACTTTGTTTTGCTGTTGGTTTTATTTTCAATTTCTTGAAAAAAAATGTTCAGTTGGCTCAGGTGCAGAGGAATTCTGAGGCGATATGTAGTAAGCTACTTCTACCTGCCACTGTTGTTACCATAATCCACCCACTCATAAAAAATTTGTTCTTCCAAAGCCATTTATCCATAACCCCTACTGACTGCATTAGTATGTAATGTCTCATCAAGAAATGTGTGTTTTGTGACTCAAACAATTATAAATTTGCAGTGTATTTTCAAAATGTAAGTCTGTTTACCTCCCCTAGATTTTTTTTTATCCAGTGACAAACTATAGGAAGGTGGGTGTACGGAAGTTTCCCATGATATTGCAGAACTATCATTTATCAAAGGAATCCATCCAGGTTGAAATATGGATCTCTAAGGGCAGGAGTTTCTAAAGTTACGTTTTTCTTTCTTCTTATTTAACATGAAATTTTCATTTTGCACTTCATTAACACGCAGTACACAGTGTACTGGAGCAAAATCATGGCGAATATGCTGTTTCTGGGGGGGGGGGGGCAAAGGGTGTAAACTGAAAAAATAAAACAGTAAACCAATTTAAAAAAAAAAAAAAAAAAAAAAAAAAAA
Protein		Refseq >NP_001030290\|T-box transcription factor TBX1 [Xenopus (Silurana) tropicalis] MISAISSPWLTQLSHFCDVAAFTANSLSSLNASGGYHLSPSPGDPYSQHEPHYEPCSASQHSYSFGHACPEPESGASSSSCASSTPGSGSTGSSGSSKAPVKKNPKVANITVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKIFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDPEDWPRNHRPGSLPLMNAFARSRNPVSSPPQNGSDKDGDGRREYERDTSGTPLHGDAAHQQLMSRVLSPSLPVPGGLVPLSTGRPSPPHELRLDPHSQGSEPLHHHPYKYPTSYDHYLGAKTRPAPYPLPSIRGHGYHHHPMNPAAANMYSGAGAPGSYEYGPR UniProtKB	Refseq >NP_001083914\|T-box transcription factor TBX1-A [Xenopus laevis] MISAISSPWLTQLSHFCDVAAFTANSLSSLNATGGYHLSPSPGDPYSQHEPHYEPCSASQHSYSFGHACPEPESGASSSSCASSTPGSGSTGSSSSNKAPVKKNPKVANINVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKIFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDPEDWPRNHRPGSLPLMNAFARSRNPVSSPTQNGSDKDGDGRREYERDASGTPLHGDAAHQQLMSRVLSLSLPVPGGLVPLSTGRPSPPHELRLDPHSQGSEPLHHHPYKYPTSYDRYLGAKTRPAPYPLPTIRGHGYHHHHMNPAAANMYSGAGAPGSYEYGPR UniProtKB		Refseq >NP_001090144\|T-box transcription factor TBX1-B [Xenopus laevis] MISAISSPWLTQLSHFCDVAAFTANSLSSLNASGGYHLSPSPGDPYSQHEPHYEPCSASQHSYSFGHACPEPESGASSSSCASSTPGSGSTGSSSGNKAPVKKNPKVANITVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKIFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDPEDWPRNHRPGSLPLMNAFARSRNPVSSPPQNGSDKDGDGRREYERDASVTPLHGDAAHQQLMSRVLSPSLPVPGGLVPLSTGRPSPPHELRLDPHSQGSEPLHHHPYKYPTSYDHYLGAKTRPAPYPLPSIRGHGYHHHPMNPAAANMYSGAGAPGGYEYGPR UniProtKB

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis a		laevis b
UniGene		Str.49461	Xl.51448 [+] Xl.12408		Xl.85545 [+] Xl.64522
Unigene EST Profile		EST Profile	EST Profile		EST Profile
GEO data			GEO		GEO
Images		18 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	TBX1	OMIM:217095 OMIM:188400 OMIM:192430
mouse		MGI	Tbx1	All(18) Targeted, knock Out(5) Targeted, other(12) Spontaneous(1)
zebrafish		ZFIN	tbx1	9 Lines(s)

Publications
First:		Isolation and characterization of a gene from the DiGeorge chromosomal region homologous to the mouse Tbx1 gene. [Genomics 1997]
Most recent:		Myogenic waves and myogenic programs during Xenopus embryonic myogenesis. [Dev Dyn 2012]
		View All Papers 3 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		transcription factor activity
Biological:		regulation of transcription, DNA-dependent
Cellular Component:		nucleus
EC:
KOG:		[K] TBX1 and related T-box transcription factors

Reagents		tropicalis	laevis a		laevis b
Clones					EXRC - 1 clone(s)
		open biosystems	open biosystems		open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes		geneservice/RZPD imagenes
Affymetrix 1.0		Str.49461.1.S1_at [+] Str.49461.1.S2_at	Xl.21661.1.S1_at		Xl.13224.1.A1_at
Affymetrix 2.0			Xl2.21661.1.S1_s_at [+] Xl2.21661.1.S1_at Xl2.12408.1.A1_at		Xl2.51448.1.S1_at

Symbol legend[+]