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Summary Expression Phenotypes Gene Literature (33) GO Terms (38) Nucleotides (88) Proteins (41) Interactants (413) Wiki
XB-GENEPAGE-478209
???displayGene.symbol???:
 fzd4

???displayGene.name???: 
frizzled class receptor 4

???displayGene.synonyms???
frizzled 4 , frizzled-4 , frizzled4 , Fz-4 , Fz4 , LOC108708760 [+] ( Nomenclature history )

???displayGene.geneFunction???
transmembrane receptor in the wnt signaling pathway

Protein Function :
Receptor for Wnt proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear...[+]


InterPro :
Frizzled dom sf, Frizzled/Smoothened TM, Frizzled dom, FZ4 CRD, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
exudative vitreoretinopathy [+]

MIM:
EXUDATIVE VITREORETINOPATHY 1; EVR1

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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