|
XB-GENEPAGE-478209
Gene Symbol:
fzd4
Gene Name: frizzled class receptor 4
Synonyms:
Fz-4
,
Xfz4
,
frizzled-4
,
frizzled 4
,
frizzled4
,
Fz4
( Gene Function: transmembrane receptor in the wnt signaling pathway Protein Function
![]()
Receptor for Wnt proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear...[+]
InterPro
![]() Interactants:
Loading ...
Diseases: Disease Ontology:
exudative vitreoretinopathy
OMIM:
EXUDATIVE VITREORETINOPATHY 1; EVR1
External Links:
|
|
Xenbase Gene ID | XB-GENE-478210 | XB-GENE-17342547 | XB-GENE-865153 | |||||
Gene Symbol | fzd4 | fzd4.L | fzd4.S | Chromosome | Chr2 | chr2L | chr2S | |
Molecules | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genomic Sequence |
Version 10.0
![]() |
Version 9.1
![]() |
Version 9.1
![]() |
|||||
CDS |
Gene model
![]() |
Gene model
![]() |
||||||
Entrez Gene |
100497693
|
399192
|
||||||
mRNA |
NCBI Nucleotide
![]() ![]() |
NCBI Nucleotide
![]() ![]() |
||||||
Protein
![]() |
![]() ![]() ![]() ![]() |
![]() ![]() ![]() ![]() |
||||||
Genomic |
X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genome Browser (Click image to open in Genome Browser) |
||||||||
Genomic Synteny | Genomicus PANTHER | |||||||
Expression | Development Stages | Embryonic Tissues | Adult Tissues | |||||
Summary for |
|
|||||||
More Information |
|
|||||||
Data Mining | X. tropicalis | X. laevis.L | X. laevis.S | |||||
XenMine | fzd4 | fzd4.L | fzd4.S | |||||
Orthology |
|
|||||||
human |
|
|||||||
mouse |
|
|||||||
rat |
|
|||||||
zebrafish |
|
|||||||
chicken |
|
|||||||
fruit fly |
|
|||||||
worm |
|
|||||||
Publications | ||||||||
First |
Xenopus frizzled 4 is a maternal mRNA and its zygotic expression is localized to the neuroectoderm and trunk lateral plate mesoderm., Mech Dev 2000 ![]() |
|||||||
Most Recent |
eGFP-tagged Wnt-3a enables functional analysis of Wnt trafficking and signaling and kinetic assessment of Wnt binding to full-length Frizzled., J Biol Chem 2020 ![]() |
|||||||
All | View All Papers 2 paper(s) referencing morpholinos 3 paper(s) referencing OMIMs 3 paper(s) referencing Disease Ontology | |||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||
GO | 12 terms | 0 term | 32 terms | |||||
PANTHER | fzd4 | |||||||
KEGG Pathways | K02354 | K02354 | ||||||
KOG |
[T] Smoothened and related G-protein-coupled receptors
|
|||||||
Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||
CRISPRscan Tracks | fzd4 | |||||||
Morpholinos | Fzd4 MO1 | Fzd4 MO1 | Fzd4 MO1 | |||||
Clones | Horizon Source BioScience | Horizon Source BioScience | ||||||
Plasmids | Addgene | Addgene |
Symbol legend:



