Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (90) GO Terms (11) Nucleotides (381) Proteins (39) Interactants (538) Wiki
XB-GENEPAGE- 478264

Gene Symbol: tcf3

Gene Name: transcription factor 3

Synonyms: e2a , itf1 , tcf-3 , xtcf3 , xtcf-3 , vdir , bhlhb21 , tcfe2a , XE12 , E12
Add Xenopus synonyms , Nomenclature history


Gene Function: helix-loop-helix transcription factor

Protein Function:
Transcriptional regulator. Cooperates with MYOD in the activation of cardiac actin gene expression. May ne involved in the initiation of neuronal differentiation. Could be functionally important in mus...[+]


Interactants: Loading ...

OMIM Disease Associations:
1/6
 
Xenbase Gene ID XB-GENE-478265 XB-GENE-865159 XB-GENE-17343115
Gene Symbol tcf3 tcf3.L tcf3.S
Chromosome scaffold_1 chr1L chr1S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0 GBrowse 9.1 JBrowse 9.1
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq TrEMBL Refseq Swiss-Prot TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene [+] Xl.3864 [+]
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 93 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine tcf3 tcf3.L tcf3.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards TCF3 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Tcf7l1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN ZFIN tcf3a tcf3b ZFIN Ensembl
chicken
GEISHA TCF3 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Methylation of adenovirus genes in transformed cells and in vitro: influence on the regulation of gene expression? [Eur J Cell Biol 1981]
Most recent: Two-Element Transcriptional Regulation in the Canonical Wnt Pathway. [Curr Biol 2017]
View All Papers 3 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs
Functional Ontologies tropicalis laevis.L laevis.S
GO 5 terms 7 terms 0 term
EC
PANTHER tcf3
KEGG Pathways K09063 K09063
KOG [K] Helix loop helix transcription factor
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones   EXRC - 6 clone(s)  
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience
Antibody Tcf3 Ab1 , Tcf3 Ab2 , Tcf3 Ab3 Tcf3 Ab1 , Tcf3 Ab2 , Tcf3 Ab3
Morpholino tcf3 MO1 tcf3 MO1 tcf3 MO1
ORF tcf3 ORF1
Affymetrix 1.0 Str.24919.2.S1_at [+] Xl.3864.1.S1_a_at [+]
Affymetrix 2.0 Xl2.3864.1.S1_a_at [+]

Symbol legend[+]

My Xenbase: [ Log-in / Register ]
version: [4.6.0]

Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556