Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (136) GO Terms (20) Nucleotides (407) Proteins (64) Interactants (1257) Wiki
XB-GENEPAGE-478264
Gene Symbol: tcf3

Gene Name: transcription factor 3

Synonyms: e2a , itf1 , tcf-3 , xtcf3 , xtcf-3 , vdir , bhlhb21 , tcfe2a , XE12 , E12 ( Add synonyms , Nomenclature history )

Gene Function: helix-loop-helix transcription factor

Protein Function :
Transcriptional regulator. Cooperates with MYOD in the activation of cardiac actin gene expression. May ne involved in the initiation of neuronal differentiation. Could be functionally important in mus...[+]


Interactants: Loading ...
OMIM Diseases: AGAMMAGLOBULINEMIA 8, AUTOSOMAL DOMINANT; AGM8

GEO Series : GSE56169.
1/6
 
Xenbase Gene ID XB-GENE-478265 XB-GENE-865159 XB-GENE-17343115
Gene Symbol tcf3 tcf3.L tcf3.S
Chromosome Chr01 chr1L chr1S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.1 Version 9.1
CDS Gene model
Entrez Gene: 100101779
Entrez Gene: 379355
mRNA RefSeq RefSeq
Protein RefSeq TrEMBL TrEMBL RefSeq Swiss-Prot TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine tcf3 tcf3.L tcf3.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards TCF3 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Tcf7l1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR ZFIN, AGR tcf3a tcf3b ZFIN Ensembl
chicken
GEISHA TCF3 Ensembl
fruit fly
worm
WORMBASE
Publications
First Methylation of adenovirus genes in transformed cells and in vitro: influence on the regulation of gene expression?, Eur J Cell Biol 1981  
Most Recent Functional characterization of pheromone receptors in the moth Athetis dissimilis (Lepidoptera: Noctuidae)., Pestic Biochem Physiol 2019  
All View All Papers 13 paper(s) referencing morpholinos 3 paper(s) referencing OMIMs 4 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 19 terms 6 terms 0 term
PANTHER tcf3
KEGG Pathways K09063 K09063
KOG [K] Helix loop helix transcription factor
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Horizon Horizon
Antibody Tcf3 Ab1 , Tcf3 Ab2 , Tcf3 Ab3 Tcf3 Ab1 , Tcf3 Ab2 , Tcf3 Ab3
Morpholino tcf3 MO1 tcf3 MO1 tcf3 MO1
ORF tcf3.L ORF1
Affymetrix 1.0 Str.24919.2.S1_at [+] Xl.3864.1.S1_a_at [+]
Affymetrix 2.0 Xl2.3864.1.S1_a_at [+]

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
Xenbase: The Xenopus laevis and X. tropicalis resource.
Version: 4.12.3


Major funding for Xenbase is provided by grant P41 HD064556