Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (909) GO Terms (20) Nucleotides (471) Proteins (87) Interactants (1313) Wiki
XB-GENEPAGE-478264
Gene Symbol:
tcf3

Gene Name:
transcription factor 3

Synonyms:
e2a , itf1 , tcf-3 , xtcf3 , xtcf-3 , vdir , bhlhb21 , tcfe2a , XE12 , E12 ( Add synonyms , Nomenclature history )

Gene Function:
helix-loop-helix transcription factor

Protein Function :
Transcriptional regulator. Cooperates with MYOD in the activation of cardiac actin gene expression. May ne involved in the initiation of neuronal differentiation. Could be functionally important in mus...[+]


InterPro :
Catenin binding dom sf , Tcf7 , TCF/LEF , CTNNB1-bd N [+]

Interactants:
Loading ...

Diseases: 


OMIM:
AGAMMAGLOBULINEMIA 8, AUTOSOMAL DOMINANT; AGM8

External Links:
GEO Series :
GSE56169.
1/6
 
Xenbase Gene ID XB-GENE-478265 XB-GENE-865159 XB-GENE-17343115
Gene Symbol tcf3 tcf3.L tcf3.S
Chromosome Chr1 chr1L chr1S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100101779
379355
380101
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More.. NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine tcf3 tcf3.L tcf3.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards TCF3 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Tcf7l1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Tcf3 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR tcf3a tcf3b ZFIN Ensembl
chicken
GEISHA TCF3 Ensembl
fruit fly
worm
Publications
First Methylation of adenovirus genes in transformed cells and in vitro: influence on the regulation of gene expression?, Eur J Cell Biol 1981  
Most Recent The Tudor-domain protein TDRD7, mutated in congenital cataract, controls the heat shock protein HSPB1 (HSP27) and lens fiber cell morphology., Hum Mol Genet 2020                          
All View All Papers 13 paper(s) referencing morpholinos 5 paper(s) referencing OMIMs 5 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 19 terms 6 terms 1 terms
PANTHER tcf3
KEGG Pathways K09063 K09063 K09063
KOG [K] Helix loop helix transcription factor
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks tcf3
Antibodies Tcf3 Ab1 , Tcf3 Ab2 , Tcf3 Ab3 Tcf3 Ab1 , Tcf3 Ab2 , Tcf3 Ab3
Morpholinos tcf3 MO1 tcf3 MO1 tcf3 MO1
ORFs tcf3.L ORF1 tcfe2a-prov ORF1
Clones Horizon Horizon Source BioScience Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list