Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (51) GO Terms (10) Nucleotides (365) Proteins (40) Interactants (990) Wiki
XB-GENEPAGE-478451
Gene Symbol: crx

Gene Name: cone-rod homeobox

Synonyms: otx5 , Xotx5 , Xotx5b , otx5b , crx-a , crx-b ( Add synonyms , Nomenclature history )

Gene Function: homeodomain transcription factor

Protein Function :
Transcription factor involved in anterior and eye development. Promotes the differentiation of both rod and cone photoreceptors cells in the retina. Together with other retinal homeobox proteins, acts ...[+]


Interactants: Loading ...
Disease Ontology: cone-rod dystrophy 2 [+]

OMIM Diseases: CONE-ROD DYSTROPHY 2; CORD2 [+]

1/5
 
Xenbase Gene ID XB-GENE-478452 XB-GENE-865179 XB-GENE-6252876
Gene Symbol crx crx.L crx.S
Chromosome Chr08 chr8L chr8S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene: 548775
Entrez Gene: 398118
Entrez Gene: 373653
mRNA RefSeq RefSeq RefSeq
Protein RefSeq Swiss-Prot TrEMBL TrEMBL RefSeq TrEMBL Swiss-Prot RefSeq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine crx crx.L crx.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards CRX OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Crx MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR crx ZFIN Ensembl
chicken
GEISHA OTX5 Ensembl
fruit fly
worm
WORMBASE
Publications
First Gene expression screening in Xenopus identifies molecular pathways, predicts gene function and provides a global view of embryonic patterning., Mech Dev 1998                                                              
Most Recent Morpholinos Do Not Elicit an Innate Immune Response during Early Xenopus Embryogenesis., Dev Cell 2019          
All View All Papers 6 paper(s) referencing morpholinos 2 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 10 terms 9 terms 8 terms
PANTHER crx
KEGG Pathways K09326 K09326 K18490
KOG [K] Homeobox transcription factor
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Horizon Horizon Horizon
Antibody Crx Ab1 Crx Ab1 Crx Ab1
Morpholino crx MO1 crx MO1 crx MO1
ORF crx.L ORF1 crx.S ORF1
Affymetrix 1.0 Str.2944.1.S1_at [+] Xl.511.1.S1_at Xl.917.1.S1_at [+]
Affymetrix 2.0 Xl2.511.2.S1_a_at [+] Xl2.42160.1.S2_at [+]

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
Xenbase: The Xenopus laevis and X. tropicalis resource.
Version: 4.12.2


Major funding for Xenbase is provided by grant P41 HD064556