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Summary Expression Gene Literature (19) GO Terms (27) Nucleotides (192) Proteins (31) Interactants (279) Wiki
XB-GENEPAGE-478586
Gene Symbol:
tgfbr1

Gene Name:
transforming growth factor beta receptor I

Synonyms:
aat5 , alk5 , skr4 , alk-5 , lds1a , lds2a , tgfr-1 , acvrlk4 , xTrR-1 , TrR-1 ( Add synonyms , Nomenclature history )

Gene Function:
serine/threonine kinase

Protein Function :
Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sod...[+]



Interactants:
Loading ...

Diseases: 


Disease Ontology:
autosomal dominant auditory neuropathy 1

OMIM:
AUDITORY NEUROPATHY, AUTOSOMAL DOMINANT, 1; AUNA1 [+]

External Links:
 
Xenbase Gene ID XB-GENE-478587 XB-GENE-17333207 XB-GENE-865194
Gene Symbol tgfbr1 tgfbr1.L tgfbr1.S
Chromosome Chr06 chr6L chr6S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.1 Version 9.2
CDS Gene model Gene model
Entrez Gene 548715
399295
mRNA RefSeq RefSeq
Protein RefSeq RefSeq
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine tgfbr1 tgfbr1.L tgfbr1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards TGFBR1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Tgfbr1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Tgfbr1 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR tgfbr1a tgfbr1b ZFIN Ensembl
chicken
GEISHA TGFBR1 Ensembl
fruit fly
worm
Publications
First A type 1 serine/threonine kinase receptor that can dorsalize mesoderm in Xenopus., Proc Natl Acad Sci U S A 1995            
Most Recent Similarity in gene-regulatory networks suggests that cancer cells share characteristics of embryonic neural cells., J Biol Chem 2017          
All View All Papers 3 paper(s) referencing morpholinos 2 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 27 terms 0 term 5 terms
PANTHER tgfbr1
KEGG Pathways K04674 K04674
KOG [T] Activin A type IB receptor, serine/threonine protein kinase
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks tgfbr1
ORFs tgfbr1.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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