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Summary Expression Gene Literature (26) GO Terms (19) Nucleotides (284) Proteins (44) Interactants (262) Wiki
XB-GENEPAGE-478638
Gene Symbol:
dact1

Gene Name:
dishevelled-binding antagonist of beta-catenin 1

Synonyms:
XDpr , Dapper , dapper 1 , frodo , dapper1 , dpr , dpr1 , hdpr1 , thyex3 , dact1-b , dact1-a ( Add synonyms , Nomenclature history )

Gene Function:
antagonist of beta-catenin and c-jun N-terminal kinase signaling

Protein Function :
Involved in regulation of intracellular signaling pathways during development. Specifically thought to play a role in canonical and/or non-canonical Wnt signaling pathways through interaction with DSH ...[+]



Interactants:
Loading ...

Diseases: 


OMIM:
TOWNES-BROCKS SYNDROME 2; TBS2

External Links:
 
Xenbase Gene ID XB-GENE-478639 XB-GENE-478643 XB-GENE-6251608
Gene Symbol dact1 dact1.L dact1.S
Chromosome Chr08 chr8L chr8S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 493325
399186
398315
mRNA RefSeq NCBI Nucleotide RefSeq
Protein RefSeq Swiss-Prot Swiss-Prot NCBI Protein RefSeq
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine dact1 dact1.L dact1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards DACT1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Dact1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Dact1 Ensembl
zebrafish
ZFIN, AGR dact1 ZFIN Ensembl
chicken
GEISHA DACT1 Ensembl
fruit fly
worm
Publications
First Dapper, a Dishevelled-associated antagonist of beta-catenin and JNK signaling, is required for notochord formation., Dev Cell 2002    
Most Recent RARĪ³ is required for mesodermal gene expression prior to gastrulation in Xenopus., Development 2018                            
All View All Papers 2 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 13 terms 6 terms 6 terms
PANTHER dact1
KEGG Pathways K22154 K22154 K22154
KOG
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks dact1
Morpholinos dact1 MO1 , dact1 MO2 , dact1 MO3 dact1 MO1 , dact1 MO2 , dact1 MO3 dact1 MO1 , dact1 MO2 , dact1 MO3
ORFs dact1.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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