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Summary Expression Gene Literature (4) GO Terms (8) Nucleotides (535) Proteins (50) Interactants (160) Wiki
XB-GENEPAGE-478727
Gene Symbol:
impdh2

Gene Name:
IMP (inosine 5'-monophosphate) dehydrogenase 2

Synonyms:
imp2 ( Add synonyms , Nomenclature history )

Gene Function:
rate-limiting enzyme in de novo guanine nucleotide biosynthesis

Protein Function :
Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays ...[+]



Interactants:
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Diseases: 


OMIM:
IMPDH2 ENZYME ACTIVITY, VARIATION IN; IMPDH2V

External Links:
 
Xenbase Gene ID XB-GENE-478728 XB-GENE-17345296 XB-GENE-478732
Gene Symbol impdh2 impdh2.L impdh2.S
Chromosome Chr4 chr4L chr4S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 493428
399236
398453
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine impdh2 impdh2.L impdh2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards IMPDH2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Impdh2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Impdh2 Ensembl
zebrafish
ZFIN, AGR impdh2 ZFIN Ensembl
chicken
GEISHA IMPDH2 Ensembl
fruit fly
Publications
First A family of IGF-II mRNA binding proteins (IMP) involved in RNA trafficking., Scand J Clin Lab Invest Suppl 2001  
Most Recent Xenopus cDNA microarray identification of genes with endodermal organ expression., Dev Dyn 2007                      
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 8 terms 6 terms 6 terms
PANTHER impdh2
KEGG Pathways K00088 K00088 K00088
KOG [F] IMP dehydrogenase/GMP reductase
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks impdh2
ORFs impdh2 ORF1 impdh2.L ORF1 impdh2.S ORF1
Clones Horizon Source BioScience Horizon Horizon Source BioScience
Plasmids Addgene Addgene

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