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XB-GENEPAGE-
478760
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Gene Symbol: six3
Gene Name: SIX homeobox 3 Synonyms: XSix3 , hpe2 , six3-a , six3-b Add Xenopus synonyms , Nomenclature history Gene Function: homeodomain transcription factor Protein Function  :
Interactants: Loading ... 
Disease Ontology Associations: HOLOPROSENCEPHALY 2 OMIM Disease Associations: SINE OCULIS HOMEOBOX, DROSOPHILA, HOMOLOG OF, 3; SIX3 |
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1/3 | Xenbase Gene ID | XB-GENE-478761 | XB-GENE-478765 | XB-GENE-17343547 | ||||
| Gene Symbol | six3 | six3.L | six3.S | ||||
| Chromosome | Chr05 | chr5L | chr5S | ||||
| Molecules | tropicalis | laevis.L | laevis.S | ||||
| Gene |
Genomic sequence
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Genomic sequence
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Genomic sequence
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| CDS |
Gene model
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Entrez Gene
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Entrez Gene
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| mRNA |
NCBI Nucleotide
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Refseq
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| Protein
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NCBI Protein
TrEMBL
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Refseq
TrEMBL
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| Genomic | tropicalis | laevis.L | laevis.S | ||||
| Genome Browser |
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| Links |
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| Genomic Synteny | Genomicus | ||||||
| Expression | tropicalis | laevis.L | laevis.S | ||||
| Ensembl | Ensembl | ||||||
| UniGene | Xl.627 | ||||||
| RNA-Seq profile | Stage profile: |
Stage profile:
Tissue heatmap:
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| Experimental regulation |
Regulation heatmap:
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| Images | 61 expression image(s) for tropicalis and laevis | ||||||
| Data Mining | tropicalis | laevis.L | laevis.S | ||||
| XenMine | six3 | six3.L | six3.S | ||||
| Phenotype | tropicalis | laevis.L | laevis.S | ||||
| Smith Morpholino Screen | |||||||
| Orthology |
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| human |
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| mouse |
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| zebrafish |
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| chicken |
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| fruit fly |
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| worm |
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| Publications | |||||||
| First: | Ectopic lens induction in fish in response to the murine homeobox gene Six3. [Mech Dev 1996] | ||||||
| Most recent: | Specific induction of cranial placode cells from Xenopus ectoderm by modulating the levels of BMP, Wnt and FGF signaling. [Genesis 2017] | ||||||
| View All Papers 18 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 4 paper(s) referencing Disease Ontologies | |||||||
| Functional Ontologies | tropicalis | laevis.L | laevis.S | ||||
| GO | 5 terms | 5 terms | 0 term | ||||
| PANTHER | six3 | ||||||
| KEGG Pathways | K19473 | ||||||
| KOG |
[K] Transcription factor SIX and related HOX domain proteins
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| Reagents | tropicalis | laevis.L | laevis.S | ||||
| CRISPR / TALEN | CRISPR tools | CRISPR tools | CRISPR tools | ||||
| Clones | |||||||
| GE Dharmacon | GE Dharmacon | GE Dharmacon | |||||
| Source BioScience | |||||||
| Morpholino | six3 MO1 , six3 MO2 , six3 MO3 | six3 MO1 , six3 MO2 , six3 MO3 | six3 MO1 , six3 MO2 , six3 MO3 | ||||
| Affymetrix 1.0 | StrEns.874.1.S1_at | Xl.627.1.S1_at | |||||
| Affymetrix 2.0 | Xl2.627.1.S1_at | ||||||
Symbol legend[+]
