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Summary Expression Gene Literature (78) GO Terms (5) Nucleotides (46) Proteins (23) Interactants (1263) Wiki
XB-GENEPAGE- 478760

Gene Symbol: six3

Gene Name: SIX homeobox 3

Synonyms: XSix3 , hpe2 , six3-a , six3-b
Add Xenopus synonyms , Nomenclature history

Gene Function: homeodomain transcription factor

Protein Function :


Interactants: Loading ...

Disease Ontology:
   HOLOPROSENCEPHALY 2

OMIM Diseases:
   HOLOPROSENCEPHALY 2; HPE2 [+]
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Xenbase Gene ID XB-GENE-478761 XB-GENE-478765 XB-GENE-17343547
Gene Symbol six3 six3.L six3.S
Chromosome Chr05 chr5L chr5S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide Refseq
Protein NCBI Protein TrEMBL Refseq TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus PANTHER
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Xl.627
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 61 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine six3 six3.L six3.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards SIX3 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Six3 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR ZFIN, AGR six3a six3b ZFIN Ensembl
chicken
GEISHA SIX3 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Ectopic lens induction in fish in response to the murine homeobox gene Six3. [Mech Dev 1996]
Most recent: Specific induction of cranial placode cells from Xenopus ectoderm by modulating the levels of BMP, Wnt and FGF signaling. [Genesis 2017]
View All Papers 18 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 4 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 5 terms 5 terms 0 term
PANTHER six3
KEGG Pathways K19473
KOG [K] Transcription factor SIX and related HOX domain proteins
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience
Morpholino six3 MO1 , six3 MO2 , six3 MO3 six3 MO1 , six3 MO2 , six3 MO3 six3 MO1 , six3 MO2 , six3 MO3
Affymetrix 1.0 StrEns.874.1.S1_at Xl.627.1.S1_at
Affymetrix 2.0 Xl2.627.1.S1_at

Symbol legend[+]
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