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Summary Expression Gene Literature (794) GO Terms (10) Nucleotides (229) Proteins (32) Interactants (1828) Wiki
XB-GENEPAGE- 478788

Gene Symbol: t

Gene Name: T brachyury transcription factor

Synonyms: Xbra , X-bra , bra , Xbrachyury , brachyury , ntl , t-a , t-b
Add Xenopus synonyms , Nomenclature history


Gene Function: T-box transcription factor

Protein Function:
Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation. Causes dorsal mesodermal differentiation of animal cap ectoderm when co-expressed with wnt8 and ...[+]


Interactants: Loading ...

OMIM Disease Associations: NEURAL TUBE DEFECTS
1/6
 
Xenbase Gene ID XB-GENE-478789 XB-GENE-6255736 XB-GENE-865212
Gene Symbol t t.L t.S
Chromosome scaffold_5 chr5L chr5S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq TrEMBL Refseq TrEMBL Refseq Swiss-Prot TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.55517 [+] Xl.7970 Xl.514
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 459 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine t t.L t.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen tgas116l23      
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards T OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI T MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN tb ta ZFIN Ensembl
chicken
GEISHA T Ensembl
fruit fly
FLYBASE t Ensembl
worm
WORMBASE
Publications
First: Expression pattern of the mouse T gene and its role in mesoderm formation. [Nature 1990]
Most recent: Evo-engineering and the cellular and molecular origins of the vertebrate spinal cord. [Dev Biol 2017]
View All Papers 195 paper(s) referencing morpholinos 4 paper(s) referencing OMIMs
Functional Ontologies tropicalis laevis.L laevis.S
GO 4 terms 4 terms 10 terms
EC
PANTHER t
KEGG Pathways K10172 K10172 K10172
KOG [K] TBX2 and related T-box transcription factors
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones EXRC - 2 clone(s)   EXRC - 2 clone(s)
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience Source BioScience
Antibody T Ab1 , T Ab2 T Ab1 , T Ab2 T Ab1 , T Ab2
Morpholino t MO1 , t MO2 , t MO3 , t MO4 t MO1 , t MO2 , t MO3 , t MO4 t MO1 , t MO2 , t MO3 , t MO4
ORF t ORF2 t ORF1
Affymetrix 1.0 Str.10814.1.S1_a_at [+] Xl.514.1.S1_at
Affymetrix 2.0 Xl2.7970.1.S1_at Xl2.514.1.S1_at

Symbol legend[+]

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