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Summary Expression Gene Literature (869) GO Terms (10) Nucleotides (234) Proteins (33) Interactants (2482) Wiki
XB-GENEPAGE-478788

Gene Symbol: tbxt

Gene Name: T-box transcription factor T

Synonyms: Xbra , X-bra , bra , Xbrachyury , brachyury , ntl , t-a , t-b , t ( Add Xenopus synonyms , Nomenclature history )

Gene Function: nuclear transcription factor

Protein Function :
Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation. Causes dorsal mesodermal differentiation of animal cap ectoderm when co-expressed with wnt8 and ...[+]

Interactants: Loading ...
Disease Ontology:

OMIM Diseases: NEURAL TUBE DEFECTS, SUSCEPTIBILITY TO; NTD [+]

GEO Series: GSE48663.
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Xenbase Gene ID XB-GENE-478789 XB-GENE-6255736 XB-GENE-865212
Gene Symbol tbxt tbxt.L tbxt.S
Chromosome Chr05 chr5L chr5S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq TrEMBL TrEMBL Refseq TrEMBL Refseq Swiss-Prot TrEMBL Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine tbxt tbxt.L tbxt.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen tgas116l23      
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards TBXT OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR T MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR tbxtb tbxta ZFIN Ensembl
chicken
GEISHA TBXT Ensembl
fruit fly
FLYBASE t Ensembl
worm
WORMBASE
Publications
First Identification of regulatory sequences in the prelude sequences of an H2A histone gene by the study of specific deletion mutants in vivo., Proc Natl Acad Sci U S A 1980  
Most Recent A dual function of FGF signaling in Xenopus left-right axis formation., Development 2019  
All View All Papers 205 paper(s) referencing morpholinos 11 paper(s) referencing OMIMs 17 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 4 terms 4 terms 10 terms
PANTHER tbxt
KEGG Pathways K10172 K10172 K10172
KOG [K] TBX2 and related T-box transcription factors
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones EXRC - 2 clone(s)   EXRC - 2 clone(s)
Dharmacon Dharmacon Dharmacon
Antibody T Ab1 , T Ab2 T Ab1 , T Ab2 T Ab1 , T Ab2
Morpholino t MO1 , tbxt MO2 , tbxt MO3 , t MO4 t MO1 , tbxt MO2 , tbxt MO3 , t MO4 t MO1 , tbxt MO2 , tbxt MO3 , t MO4
ORF tbxt ORF1 tbxt.L ORF1 tbxt.S ORF1
Affymetrix 1.0 Str.10814.1.S1_a_at [+] Xl.514.1.S1_at
Affymetrix 2.0 Xl2.7970.1.S1_at Xl2.514.1.S1_at

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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