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Summary Expression Gene Literature (40) GO Terms (12) Nucleotides (313) Proteins (18) Interactants (283) Wiki
XB-GENEPAGE- 478821

Gene Symbol: map2k1

Gene Name: mitogen-activated protein kinase kinase 1

Synonyms: mek1
Add Xenopus synonyms , Nomenclature history


Gene Function: serine/threonine kinase

Protein Function:
Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Binding of extracellular ligands such as growth factors, cytokines and hormones to th...[+]


Interactants: Loading ...

OMIM Disease Associations: CARDIOFACIOCUTANEOUS SYNDROME 3; CFC3
 
Xenbase Gene ID XB-GENE-478822 XB-GENE-865216 XB-GENE-17341792
Gene Symbol map2k1 map2k1.L map2k1.S
Chromosome scaffold_3 chr3L chr3S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0 GBrowse 9.1 JBrowse 9.1
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq TrEMBL Refseq Swiss-Prot TrEMBL TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.50744 Xl.5877
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 1 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine map2k1 map2k1.L map2k1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards MAP2K1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Map2k1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN map2k1 ZFIN Ensembl
chicken
GEISHA MAP2K1 Ensembl
fruit fly
worm
WORMBASE
Publications
First: MAP kinase-dependent pathways in cell cycle control. [Prog Cell Cycle Res 1995]
Most recent: Phosphorylation Dynamics Dominate the Regulated Proteome during Early Xenopus Development. [Sci Rep 2017]
View All Papers 3 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs
Functional Ontologies tropicalis laevis.L laevis.S
GO 9 terms 6 terms 2 terms
EC Phosphotransferases with an Alcohol Group as Acceptor
PANTHER map2k1
KEGG Pathways K04368 K04368 K04368
KOG [T] Mitogen-activated protein kinase kinase (MAP2K)
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Antibody map2k1 Ab1 map2k1 Ab1 map2k1 Ab1
Morpholino map2k1 AGT MO1 , map2k1 MO2 map2k1 AGT MO1 , map2k1 MO2 map2k1 AGT MO1 , map2k1 MO2
ORF map2k1 ORF1
Affymetrix 1.0 Str.10686.1.S1_a_at [+] Xl.5877.1.S1_at
Affymetrix 2.0 Xl2.5877.1.S1_at

Symbol legend[+]

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