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Summary Expression Gene Literature (308) GO Terms (25) Nucleotides (221) Proteins (42) Interactants (454) Wiki
XB-GENEPAGE-478849
Gene Symbol:
acvr1

Gene Name:
activin A receptor type 1

Synonyms:
alk2 , alk-2 , fop , skr1 , tsri , actri , acvr1a , acvrlk2 , sax , alk8 , acvr1-b , acvr1-a , XAR4 ( Add synonyms , Nomenclature history )

Gene Function:
activin receptor, serine/threonine protein kinase

Protein Function :


InterPro :
P-loop NTPase , Kinase-like dom sf , Ser-Thr/Tyr kinase cat dom , TGFB receptor [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
fibrodysplasia ossificans progressiva

OMIM:
FIBRODYSPLASIA OSSIFICANS PROGRESSIVA; FOP

External Links:
1/3
 
Xenbase Gene ID XB-GENE-478850 XB-GENE-6254423 XB-GENE-865219
Gene Symbol acvr1 acvr1.L acvr1.S
Chromosome Chr9 chr9_10L chr9_10S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 550111
399103
399083
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine acvr1 acvr1.L acvr1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards ACVR1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Acvr1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Acvr1 Ensembl
zebrafish
ZFIN, AGR acvr1l ZFIN Ensembl
chicken
GEISHA ATVR1 Ensembl
fruit fly
worm
Publications
First Activin receptors: cellular signalling by receptor serine kinases., Biochem Soc Symp 1996  
Most Recent Natural size variation among embryos leads to the corresponding scaling in gene expression., Dev Biol 2020                      
All View All Papers 5 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 25 terms 4 terms 4 terms
PANTHER acvr1
KEGG Pathways K04675 K04675 K04675
KOG [T] Activin A type IB receptor, serine/threonine protein kinase
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks acvr1
Morpholinos acvr1 MO1 acvr1 MO1 acvr1 MO1
ORFs acvr1.L ORF1 acvr1.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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