Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (14) GO Terms (27) Nucleotides (121) Proteins (32) Interactants (113) Wiki
XB-GENEPAGE-479063
Gene Symbol:
psmb8

Gene Name:
proteasome subunit beta 8

Synonyms:
low molecular mass protein-7 (LMP-7) homolog , lmp7 ( Add synonyms , Nomenclature history )

Gene Function:
20S proteasome, regulatory subunit

Protein Function :
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basi...[+]



Interactants:
Loading ...

Diseases: 


Disease Ontology:
JMP syndrome

OMIM:
PROTEASOME-ASSOCIATED AUTOINFLAMMATORY SYNDROME 1; PRAAS1

External Links:
 
Xenbase Gene ID XB-GENE-479064 XB-GENE-479068 XB-GENE-17333567
Gene Symbol psmb8 psmb8.L psmb8.S
Chromosome Sca23 chr8L
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2
CDS Gene model Gene model
Entrez Gene 445258
399439
mRNA RefSeq RefSeq
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine psmb8 psmb8.L psmb8.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards PSMB8 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Psmb8 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Psmb8 Ensembl
zebrafish
ZFIN, AGR psmb8a ZFIN Ensembl
chicken
fruit fly
worm
Publications
First Evolution of proteasome subunits delta and LMP2: complementary DNA cloning and linkage analysis with MHC in lower vertebrates., J Immunol 1997  
Most Recent Coevolution of MHC genes (LMP/TAP/class Ia, NKT-class Ib, NKp30-B7H6): lessons from cold-blooded vertebrates., Immunol Rev 2015  
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 27 terms 6 terms 0 term
PANTHER psmb8
KEGG Pathways K02740 K02740
KOG [O] 20S proteasome, regulatory subunit beta type PSMB5/PSMB8/PRE2
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks psmb8
ORFs psmb8 ORF1 psmb8.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
Xenbase: The Xenopus Model Organism Knowledgebase.
Version: 4.15.0
Major funding for Xenbase is provided by grant P41 HD064556