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Summary Expression Gene Literature (82) GO Terms (14) Nucleotides (171) Proteins (48) Interactants (281) Wiki
XB-GENEPAGE-479124
Gene Symbol:
slc4a4

Gene Name:
solute carrier family 4 member 4

Synonyms:
XNBC1 , nbc1 , nbce1 , hnbc1 , nbc2 , pNBC , hhNMC , slc4a5 ( Add synonyms , Nomenclature history )

Gene Function:
transmembrane solute exchange

Protein Function :



Interactants:
Loading ...

Diseases: 


OMIM:
RENAL TUBULAR ACIDOSIS, PROXIMAL, WITH OCULAR ABNORMALITIES AND MENTAL RETARDATI

External Links:
1/5
 
Xenbase Gene ID XB-GENE-479125 XB-GENE-6486666 XB-GENE-17343287
Gene Symbol slc4a4 slc4a4.L slc4a4.S
Chromosome Chr1 chr1L chr1S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100490445
108711128
108706771
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein  More.. NCBI Protein NCBI Protein  More.. NCBI Protein NCBI Protein  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine slc4a4 slc4a4.L slc4a4.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards SLC4A4 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Slc4a4 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Slc4a4 Ensembl
zebrafish
ZFIN, AGR slc4a4a slc4a4b ZFIN Ensembl
chicken
GEISHA SLC4A4 Ensembl
fruit fly
worm
Publications
First Molecular cloning, chromosomal localization, tissue distribution, and functional expression of the human pancreatic sodium bicarbonate cotransporter., J Biol Chem 1998  
Most Recent Carbonic anhydrases enhance activity of endogenous Na-H exchangers and not the electrogenic Na/HCO3 cotransporter NBCe1-A, expressed in Xenopus oocytes., J Physiol 2020  
All View All Papers 7 paper(s) referencing morpholinos 5 paper(s) referencing OMIMs 7 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 14 terms 2 terms 2 terms
PANTHER slc4a4
KEGG Pathways
KOG [P] Na+-independent Cl/HCO3 exchanger AE1 and related transporters (SLC4 family)
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks slc4a4
Clones Horizon Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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