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Summary Expression Gene Literature (129) GO Terms (11) Nucleotides (129) Proteins (41) Interactants (525) Wiki
XB-GENEPAGE-479143
Gene Symbol:
lmo2

Gene Name:
LIM domain only 2

Synonyms:
LMO-2 , xlmo2 , xlmo-2 ( Add synonyms , Nomenclature history )

Gene Function:
transcription factor

Protein Function :
Transcription factor that acts synergistically with tal1/scl and gata1 to specify embryonic dorsal mesoderm to a hematopoietic fate. Induces globin gene expression together with fgf.


InterPro :
SPRR/LCE , Znf LIM

Interactants:
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Diseases: 


External Links:
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Xenbase Gene ID XB-GENE-479144 XB-GENE-17336858 XB-GENE-6254426
Gene Symbol lmo2 lmo2.L lmo2.S
Chromosome Chr4 chr4L chr4S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 496679
108713784
394388
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. NCBI Protein TrEMBL RefSeq Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine lmo2 lmo2.L lmo2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards LMO2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Lmo2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Lmo2 Ensembl
zebrafish
ZFIN, AGR lmo2 ZFIN Ensembl
chicken
GEISHA LMO2 Ensembl
fruit fly
worm
Publications
First Genomic structure, alternative transcripts and chromosome location of the human LIM domain binding protein 1 gene LDB1., Cytogenet Cell Genet 1999  
Most Recent Etv6 activates vegfa expression through positive and negative transcriptional regulatory networks in Xenopus embryos., Nat Commun 2019                                                          
All View All Papers 10 paper(s) referencing morpholinos
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 10 terms 2 terms 5 terms
PANTHER lmo2
KEGG Pathways K15612 K15612 K15612
KOG [R] Transcription factor, contains HOX domain
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks lmo2
Antibodies Lmo2 Ab1 Lmo2 Ab1
Transgenes Tg(lmo2:Katushka;cryga:GFP) Tg(lmo2:Katushka;cryga:GFP) Tg(lmo2:Katushka;cryga:GFP)
ORFs lmo2 ORF1 lmo2.S ORF1
Clones Horizon Source BioScience Horizon EXRC Horizon Source BioScience
Plasmids Addgene Addgene

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