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Summary Expression Gene Literature (8) GO Terms (7) Nucleotides (101) Proteins (26) Interactants (261) Wiki
XB-GENEPAGE- 479254

Gene Symbol: fgfr3

Gene Name: fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism)

Synonyms: ach , cek2 , jtk4 , cd333 , hsfgfr3ex , fgfr-3
Add Xenopus synonyms , Nomenclature history


Gene Function: receptor tyrosine kinase

Protein Function:
Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation and apoptosis. Plays an ess...[+]


Interactants: YYY

OMIM Disease Associations: ACHONDROPLASIA; ACH [+]
 
Xenbase Gene ID XB-GENE-479255 XB-GENE-479259 XB-GENE-17330101
Gene Symbol fgfr3 fgfr3.L fgfr3.S
Chromosome scaffold_1 chr1L chr1S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0 GBrowse 9.1 JBrowse 9.1
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq TrEMBL Refseq TrEMBL Refseq Swiss-Prot Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
GBrowse
tropicalis genome v7.1 gene model
GBrowse
laevis genome v9.1 gene model
GBrowse
laevis genome v9.1 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.47509 Xl.62993 Xl.8760
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Images 8 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine fgfr3 fgfr3.L fgfr3.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen tgas092f08      
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards FGFR3 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Fgfr3 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN fgfr3 ZFIN Ensembl
chicken
GEISHA FGFR3 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Fibroblast growth factor (FGF) 3 from Xenopus laevis (XFGF3) binds with high affinity to FGF receptor 2. [J Biol Chem 1995]
Most recent: FGFR3 expression in Xenopus laevis. [Gene Expr Patterns 2010]
View All Papers 1 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 5 terms 5 terms 7 terms
EC now EC:2.7.10.1 and EC:2.7.10.2
PANTHER fgfr3
KEGG Pathways K05094 K05094 K05094
KOG [T] Fibroblast/platelet-derived growth factor receptor and related receptor tyrosine kinases
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Morpholino fgfr3 MO1 , fgfr3 MO2 fgfr3 MO1 , fgfr3 MO2 fgfr3 MO1 , fgfr3 MO2
ORF fgfr3 ORF1
Affymetrix 1.0 StrJgi.2927.1.S1_at [+] Xl.8760.1.S1_at
Affymetrix 2.0 Xl2.29689.1.S1_at Xl2.8760.1.S1_at

Symbol legend[+]

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