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XB-GENEPAGE-479317
Gene Symbol:
notch1
Gene Name: notch 1 receptor
Synonyms:
notch
,
xotch
,
xnotch
,
notch-1
,
xnotch1
,
x-notch-1
( Gene Function: signal transduction, receptor for delta class ligands Protein Function
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Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellul...[+]
Interactants:
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Diseases: Disease Ontology:
Adams-Oliver syndrome
OMIM:
AORTIC VALVE DISEASE 1; AOVD1
External Links:
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Xenbase Gene ID | XB-GENE-479318 | XB-GENE-17342057 | XB-GENE-865261 | |||||
Gene Symbol | notch1 | notch1.L | notch1.S | Chromosome | Chr8 | chr8L | chr8S | |
Molecules | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genomic Sequence |
Version 10.0
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Version 9.1
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Version 9.1
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CDS |
Gene model
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Gene model
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Gene model
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Entrez Gene |
100037842
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108698191
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394367
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mRNA |
NCBI Nucleotide
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NCBI Nucleotide
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NCBI Nucleotide
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Protein
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Genomic |
X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genome Browser (Click image to open in Genome Browser) |
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Genomic Synteny | Genomicus PANTHER | |||||||
Expression | Development Stages | Embryonic Tissues | Adult Tissues | |||||
Summary for |
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More Information |
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Proteomics | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Embryonic Protein Expression | Stage profile:![]() |
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Data Mining | X. tropicalis | X. laevis.L | X. laevis.S | |||||
XenMine | notch1 | notch1.L | notch1.S | |||||
Orthology |
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mouse |
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rat |
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zebrafish |
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chicken |
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fruit fly |
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worm |
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Publications | ||||||||
First |
Cell patterning in pigment-chimeric eyes in Xenopus: germinal transplants and their contributions to growth of the pigmented retinal epithelium., Proc Natl Acad Sci U S A 1987 ![]() |
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Most Recent |
Notch signaling induces either apoptosis or cell fate change in multiciliated cells during mucociliary tissue remodeling., Dev Cell 2020 ![]() |
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All | View All Papers 53 paper(s) referencing morpholinos 6 paper(s) referencing OMIMs 15 paper(s) referencing Disease Ontology | |||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||
GO | 15 terms | 12 terms | 11 terms | |||||
PANTHER | notch1 | |||||||
KEGG Pathways | K02599 | K02599 | K02599 | |||||
KOG |
[O] 26S proteasome regulatory complex, subunit PSMD10
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Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||
CRISPRscan Tracks | notch1 | |||||||
Antibodies | Notch1 AB1 | Notch1 AB1 | Notch1 AB1 | |||||
Morpholinos | notch1 MO1 | notch1 MO1 | notch1 MO1 | |||||
Clones | Horizon Source BioScience | Horizon | EXRC Horizon Source BioScience | |||||
Plasmids | Addgene | Addgene |
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