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Summary Expression Gene Literature (365) GO Terms (16) Nucleotides (207) Proteins (34) Interactants (1416) Wiki
Gene Symbol: notch1

Gene Name: notch 1 receptor

Synonyms: notch , xotch , xnotch , notch-1 , xnotch1 , x-notch-1 ( Add synonyms , Nomenclature history )

Gene Function: signal transduction, receptor for delta class ligands

Protein Function :
Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellul...[+]

Interactants: Loading ...
Diseases:  Disease Ontology: aortic valve stenosis


External Disease Links: ClinVar, MalaCards, KEGG Disease, DECIPHER

GEO Series : GSE76342.
Xenbase Gene ID XB-GENE-479318 XB-GENE-17342057 XB-GENE-865261
Gene Symbol notch1 notch1.L notch1.S
Chromosome Chr02 chr8L chr8S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100037842
mRNA RefSeq NCBI Nucleotide RefSeq
Protein RefSeq TrEMBL Swiss-Prot NCBI Protein TrEMBL RefSeq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine notch1 notch1.L notch1.S
MOD Entrez Gene Genetic Phenotypes Gene Expression
OMIM:Gene, HGNC, GeneCards NOTCH1 OMIM Ensembl, Protein Atlas, Allen Brain Atlas
MGI, AGR Notch1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
ZFIN, AGR ZFIN, AGR notch1a notch1b ZFIN Ensembl
fruit fly
First Cell patterning in pigment-chimeric eyes in Xenopus: germinal transplants and their contributions to growth of the pigmented retinal epithelium., Proc Natl Acad Sci U S A 1987            
Most Recent Hematopoiesis: from start to immune reconstitution potential., Stem Cell Res Ther null  
All View All Papers 53 paper(s) referencing morpholinos 6 paper(s) referencing OMIMs 13 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 14 terms 9 terms 11 terms
PANTHER notch1
KEGG Pathways K02599 K02599 K02599
KOG [O] 26S proteasome regulatory complex, subunit PSMD10
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks notch1
Antibodies Notch1 AB1 Notch1 AB1 Notch1 AB1
Morpholinos notch1 MO1 notch1 MO1 notch1 MO1
Clones Horizon Source BioScience Horizon EXRC Horizon Source BioScience

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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