Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (731) GO Terms (32) Nucleotides (357) Proteins (22) Interactants (1359) Wiki
XB-GENEPAGE-479466

Gene Symbol: mapk1

Gene Name: mitogen-activated protein kinase 1

Synonyms: erk , MAP kinase , erk2 , mapk , xp42 , mpk1 , ert1 , mapk2 , p42mapk , prkm1 , prkm2 , mapk1-b , mapk1-a ( Add Xenopus synonyms , Nomenclature history )

Gene Function: serine/threonine kinase

Protein Function :
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the MAPK/ERK cascade. Depending on the cellular context, this casc...[+]

Interactants: Loading ...
Disease Ontology:

OMIM Diseases:

 
Xenbase Gene ID XB-GENE-479467 XB-GENE-6252586 XB-GENE-865273
Gene Symbol mapk1 mapk1.L mapk1.S
Chromosome Chr01 chr1L chr1S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA RefSeq RefSeq RefSeq
Protein RefSeq TrEMBL TrEMBL RefSeq TrEMBL RefSeq Swiss-Prot TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine mapk1 mapk1.L mapk1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards MAPK1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Mapk1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR mapk1 ZFIN Ensembl
chicken
GEISHA MAPK3 Ensembl
fruit fly
worm
WORMBASE
Publications
First In vitro effects on microtubule dynamics of purified Xenopus M phase-activated MAP kinase., Nature 1991  
Most Recent Autophosphorylation of MAP kinase disables the MAPK pathway in apoptotic Xenopus eggs., Biochem Biophys Res Commun 2019  
All View All Papers 52 paper(s) referencing morpholinos 4 paper(s) referencing OMIMs 6 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 22 terms 3 terms 15 terms
PANTHER mapk1
KEGG Pathways K04371 K04371 K04371
KOG [T] Mitogen-activated protein kinase
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Dharmacon Dharmacon Dharmacon
Antibody Mapk1 Ab6 , Mapk1 Ab1 , Mapk1 Ab2 , Mapk1 Ab3 , Mapk1 Ab4 , Mapk1 Ab5 , Mapk1 Ab7 , Mapk1 Ab8 , Mapk1 Ab9 , Mapk1 Ab10 , Mapk Ab5 , Mapk1 Ab13 , mapk1 Ab17 Mapk1 Ab6 , Mapk1 Ab1 , Mapk1 Ab2 , Mapk1 Ab3 , Mapk1 Ab4 , Mapk1 Ab5 , Mapk1 Ab7 , Mapk1 Ab8 , Mapk1 Ab10 , Mapk Ab5 , Mapk1 Ab13 , Mapk1 Ab16 , mapk1 Ab17 Mapk1 Ab6 , Mapk1 Ab1 , Mapk1 Ab2 , Mapk1 Ab3 , Mapk1 Ab4 , Mapk1 Ab5 , Mapk1 Ab7 , Mapk1 Ab8 , Mapk1 Ab10 , Mapk Ab5 , Mapk1 Ab13 , Mapk1 Ab16 , mapk1 Ab17
ORF mapk1.L ORF1 mapk1.S ORF1
Affymetrix 1.0 Str.19446.1.S1_at [+] Xl.874.1.S1_s_at Xl.1680.1.S1_at [+]
Affymetrix 2.0 Xl2.874.1.S1_s_at [+] Xl2.1680.1.S1_at

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
Xenbase: The Xenopus laevis and X. tropicalis resource.
Version: 4.11.3


Major funding for Xenbase is provided by grant P41 HD064556