mapk1 Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (619)

Nucleotides (355)

Interactants (703)

XB-GENEPAGE-479466

Gene Symbol: mapk1 Gene Name: mitogen-activated protein kinase 1 Synonyms: erk, MAP kinase, erk2, mapk, xp42, mpk1, ert1, mapk2, p42mapk, prkm1, prkm2 Add Xenopus synonyms Gene Function: serine/threonine kinase Interactants: mos(135) , cdk1(117) , pold1(84) , ccnb1.2(72) , rps6ka3(52) , cdk20(50) , mapk14(39) View All

XB-GENE-479467

XB-GENE-865273

XB-GENE-6252586

Molecules		tropicalis	laevis a		laevis b
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene		Entrez Gene
mRNA		Refseq >NM_001017127\|Xenopus (Silurana) tropicalis mitogen-activated protein kinase 1 (mapk1), mRNA CCGTGTAATACCCACAGCAGCTCCGGAGAAACTCTCCCCGACGCATTAAATCAAGCAAAACATGGCAGCGGCAGGGGCCTCGTCTAACCCCGGCGGGGGGCCGGAGATGGTGCGAGGGCAGGCGTTCGACGTAGGCCCGCGATATACCAACCTGTCATATATCGGGGAGGGAGCGTACGGCATGGTTTGTTCTGCCTATGACAATGTAAACAAAGTACGAGTTGCTATCAAGAAAATCAGCCCATTTGAGCATCAGACATACTGCCAGAGAACACTGAGGGAGATCAAAATCTTGCTGCGTTTTAAGCATGAAAACATCATTGGAATTAATGACATAATTCGAGCTCCAACCATTGAGCAAATGAAAGATGTGTATATTGTGCAGGATCTCATGGAGACAGATCTCTATAAACTCCTGAAGACTCAGCATCTTAGCAATGACCACATCTGCTATTTCTTGTACCAGATCCTGAGAGGATTAAAGTACATCCATTCAGCCAATGTTCTACATCGTGATCTTAAGCCTTCAAATTTGCTGCTTAACACTACCTGTGATCTTAAGATTTGTGATTTTGGATTGGCTCGTGTTGCAGACCCAGACCATGATCACACTGGATTTCTCACAGAATATGTAGCCACTCGCTGGTACAGAGCTCCTGAGATCATGCTGAATTCCAAGGGCTATACCAAATCGATTGACATCTGGTCTGTTGGCTGCATTCTTGCTGAGATGCTTTCTAATAGACCCATATTTCCTGGAAAACATTATCTTGACCAACTCAATCACATACTTGGAATTCTTGGATCTCCATCTCAAGAGGACCTAAACTGTATAATCAATTTAAAAGCTAGGAATTACTTGCTTTCCCTTCCTCACAAAAATAAGGTGCCATGGAACAGACTTTTCCCTAATGCAGATCCTAAAGCTCTAGATTTATTGGACAAGATGTTGACCTTCAACCCCCACAAAAGAATTGAAGTAGAGGCAGCTTTGGCTCATCCCTATCTGGAACAATATTATGACCCAAGTGATGAGCCTGTAGCTGAAGCTCCCTTTAAATTTGAAATGGAGCTTGATGATTTGCCCAAGGAGACACTGAAGGAGCTAATTTTTGAAGAAACGGCTAGATTCCAGCCAGGGTACTGACCAACCATATGACAACAGGGAAAGGATGTGAAGGACTTTGCACGCTGAGACATCGGTGTTGTTCTTGCCAGTTCTTCCTCCTTGGGCGTGTCCTGTGCTCCATCTCAGCTTGTCCAGTCTAACTTCTTTGAGCCATTATGGAGGGCAGTTCCTGGTAGTTGTGGCTTTTTATGCTTCTGATGAATTCTTTCGATCTGGAGAATTGTTCTTGACACTCCTTTGTGAAAGTGGTGCGGCAAACACACACCTGCTGAGACCTTCATTAACCGCTTGTACATTATTATTTTTTTTTTGTATTGTTTTATAAAGATGCAGTGATTCCTTTTCATTTGTCTGGGTATACAGCACCCTGACTTTCACTGGCCCTGCACACTGTATCAAACCACACATTCAAACACTGTGGTATTTGGCATTGTGTTTTGTTTTTTCCCTCTTTCTTAGTTTTTCCTTTTTTTTTTCCTTTTTTTTTTATTTGGGAGAGTTATTCTCTGGGCACTTTAAATCAATGTAAAGCCCTATTTACTTGCACATATCATTTTAAACAAATGCAGTTGTAAGCTTTGAAATTCTAATGGAGCTTATCATATATATAACGGTTACTAGCTTTCTCTAGCACTTAGCAGAGCTGAGCAAACTATTTTACCCCTTTCCATGTTTAAGGGACCTTGTAGGTTGAAAAGATAATAATGCCCCCTAATAAAATCTATATGTGTACATGCTTAAAAAAAAAAAAAAAAAA	Refseq >NM_001090079\|Xenopus laevis mitogen-activated protein kinase 1 (mapk1-a), mRNA AACACAAGCAACGACTGAGCCAGTGCAGCGAGCCTGGGGCGCCGCCTCGTCATCCGCGTTCTCGCTCCCCACCAGAGAGACGGCCACACCCACGGAGGCGCAGACGGAACGAGCCGTGTAATCGCCGCCGCAGCAGCTCCGGAGAAACTCTCCCCACCGCATTTAATAAAGCAAAACATGGCAGCGGCAGGAGCTGCGTCTAACCCCGGCGGGGGTCCGGAGATGGTGCGGGGCCAGGCGTTCGACGTAGGCCCTCGATACATCAATCTGGCTTATATCGGCGAGGGAGCGTACGGCATGGTGTGTTCTGCCCATGACAATGTTAACAAAGTTCGAGTTGCTATCAAGAAAATCAGCCCATTTGAGCATCAGACATACTGCCAGCGAACATTGCGGGAGATCAAAATCTTGCTACGTTTTAAACATGAAAACATCATTGGGATAAACGACATTATTCGCGCTCCAACCATTGAGCAGATGAAAGATGTGTACATTGTGCAGGACCTCATGGAGACAGACCTCTATAAGCTCCTGAAGACTCAGCATCTTAGCAATGACCATATCTGCTATTTCTTGTACCAGATTCTGAGAGGATTAAAGTACATCCATTCAGCCAATGTTCTACATCGTGATCTTAAGCCTTCAAATTTGCTGCTTAACACTACCTGTGATCTCAAGATCTGTGATTTTGGATTGGCTCGTGTTGCAGACCCAGATCATGATCACACTGGCTTTCTCACAGAATATGTAGCCACTCGCTGGTACAGAGCTCCTGAGATCATGCTGAATTCCAAGGGCTATACCAAATCAATTGACATCTGGTCTGTTGGCTGCATTCTTGCTGAGATGCTTTCTAATAGACCCATATTTCCTGGGAAACATTATCTTGACCAGCTTAATCACATACTTGGTATTCTTGGATCTCCATCTCAAGAGGACCTAAACTGTATAATCAATTTAAAAGCTAGGAATTACTTGCTTTCCCTTCCTCACAAAAATAAGGTGCCATGGAACAGACTTTTCCCCAATGCAGATCCCAAAGCTCTAGACTTACTGGACAAGATGCTGACTTTCAACCCCCATAAAAGAATTGAAGTAGAGGCAGCTTTGGCTCATCCTTATCTGGAGCAGTATTATGACCCAAGTGATGAGCCTGTAGCTGAAGCTCCCTTTAAATTTGAAATGGAGCTTGATGATTTGCCCAAGGAGACTCTTAAGGAGCTAATTTTTGAAGAAACCGCTAGATTCCAGCCAGGGTACTGACCACCATCTAACCACAGGGAAAGGATGTGAAGGACTTTGCTGAGACATCGGTGTTGTTCTTGCCAGTTCTTCCTCCTTGGGCGTGTCCTGTGCTCCATCTCAGCTTGTCCAGTCTATAACTTCTTTGAGCCATTATGGAGGGCAGTTCCTGGTAGTTGTGGCTTTTTATGCTTCTGATGAATTCTTTCGATATGGAGAATTGTTCTTGACACTCCTTTGTGAAAGTGGTGCGGCAAACACACACCTGCTGAGACCTTCATTAACCGCTTGTACATTATTATTTTTTTTTTTCTTTTTGTATTGTTTTATAAAGATGCAGTGAATTTCTTTCCATTTTTCTGGGTTTACAGCACTCGGACTTTCACCGGCCCTACACGCTGTATCAAACCACACATTCAAACACTGTGGTATTTGCCATTGTTTTGGGTTTTTTGTTTATTTTTCCCCTCCTTAGTTTTTACTTTTTTTTTTTTTATTTGGGAGAGTTTTTCTCTGGGCACTTTAAATCAATGTAAAGCCCTATTTACTTGCACATATCATTTTAAACAAATGCAGTTGTAAGCATTGAAATTCTAATGGAGCTTATCATATATATATATATATAACGGTTACTAGCTTTCTCTAGCACTTAGCAGAACCGAGCAAACTATTTTAACCCTTTCCATGTTTAAGGTCGAAAAGATAATAATGCCCCCTAATAAAATGTGTGTGTACGTGCTTACAGAACTCAACCTCTCATTCTTTTAAGCTGCTGCAATATATTCAAACAGGGAAAAAAAACTTTGGGCATTTTTGCCATGCACTGGCCTTCTCTGGTCTGGGTTTTTTTCATGCATGGAGAAATAGTAGTATGTTGAATTTTACATGAGTATAAAGCAAGTGAAACCAAAATCTCGTTACTGTTAGCTGAGGAAGTTTAGAATGAGACTGTGCATTATCACTGCAGAGGTGAAATGCATGCTGTCTGTACAAAGTAAGTGTGGTTAATTTCAGCATTGGAATGAGTGCTTTGATTATAATGCTAACCGAAAGAATCTGCATCTGTAGGTAACGGCGGGTTTTCTTGTCGAGAGAGGCTCTTGTTTGTAACCAACATCTCTACTTTATTATTCTCAAACCTATATCTGCTTCATTGAGTCTGGTACCTACAGTTCTGTAGTGTCTGAAAGATATAGTAATCTTTTTCTTGCCCAGCTTGGAGCAACCCGCCAAACTAGCACTAATTTTAAACTATTAACATTTCTTTGCAAGTATTTGTTCTTGGAATTGTATAATGTGGAGTTTACTAGATGTTATGTCGAAGTGCGGTGCCTCCTCCTTCCCCCCCACCCACCTCAAGATTTGCCTTGTTTGAAATGACCGTGCCCTCGCATGACTGTTAAGCTTTTCTGTGCAAAGATGATTGTTTAAGTGCCACATGCCTTTGATGATATAAGAAAATGTGTTACCTCTGAATCATATTCAACTGAAATGTTATTCTGTAACCTACATGAGGAGAAAACGGCTCTATCTTAATCCTCTTCTCTATTCTGTCTTTCCTTGTCCGGCAGAGTTTTAACAATTTGTCTGCACTGCCTGGAAACATGAACAAAAATTGCACTTGTAAATGAAATAAATTGAAATCTTCTCATTAATTTACAGGTTTATTAATTTTTTTTTCTCCATTTAATTTGCTTTGAAAGCTGTTTCTGTGACGTTTGTGATTTCTTGCTATACATTTCTGATTTTTTTTGAGACTGACTTTTTTTTTTTTAATTATCATTAAACTAGGTGTCCAACTAATTGGCCAATTTATGTTGTCCGCTAAAAACAAAAGCCATTTTTGGTACATGTGCTTTATTATCTGACAACCCTTCTTTTTTTGTGCTTTGCTTGAAAAAGGGATTTGCTTTGCATCTAAACTTTTCCTGATCTGCCATAGACCTGCTGATCATTTCTCACGTATAAGCCACAACTGAATTTTCTCCTATACAAGTACTGCTCTTCAGTTTTGGGTACTTTTGCTGAAAGCTGGTGCTTTAATCATGTATTTTGATATGTGAATCTGGACTGATGTGGGCATCAAACATGGAGTCACTGTGCTTGTCGGAAGGCTGAAACGTCTTATTAGATCTACTATGTGATTTGATTAAAAACACAGACACCACCAAAGAGTTAGGACAAGATTTTGTGTAAACTGTTAAAACATAAGCTTCTGGCAAACATTTGGGGTTTCTGACCTATATTCCTGGACTCGCTTCATAAGATAGAAATGAAAATATACTGCTATGCACTAACACTGTTCAAACATGTTTTTCTAGTTCTCCTCAACCCTACTTATCATTTTAATTGGATGAGGGACAGGATAAGCCATATATATATATCAGTCTGAAAGGTGATTATGTAACTCATTCCAAGTAAGTGTATATCAGGAAGTGCTTGATTTCATTCAGTTCATACAGCTGATCTCTCTGCTGCATTTATACAGCATTGCAGCACTTCCAAGTCAACAAGCTGGGTGGGACCTGTATTCACCGCTCTCTCACTGCTTTGGCTCTCACTGGCAGTTGATGTATTTATTGTTAATGCTTTGTAGCCAAGCTGACGAGAATGTTCAGGATAGCTGTAATTAAGAAATCGCAAGTACTTGCAAAATGACACATCACTCCCTTTTTCTGCATCTATTATTATTATAAAAAGAAAAATATATTCCACTGCTTTGATTAGAGGTGTTTTCAGGAGCGAATGGATAGCCTTAACCTCTTGCTGCTTTTCCTTTTTTGTGGCATTGTCCCCCACTAACTGCACTTCAAATTCTGCCTTCACATCTGCTCTCTTCTCAAGCAAAATCAACACATTTCTTAGTACTGGTTGCAGTTCCATATTGACTGGACTTTTTGGAACAGAGATATCAACTGTAAATGGATACTGCCTCACGTCTCTCAACGGCTCTACATCTTTGGGATATAACAAAAAAAAAATTGCCAATCCCCAGTGCAACCTATTGCCCTTTAAACAGATTCCTTAAAGAGCTTGTACTTGCTTTGTACTGTCGGTGCCTTTTTAGTCATGTATTCAAAAAAAAATGTGTGTAGCTGACTTGGTAGACTGTACCTTTAGTAATCTTCACTGCTTGGTGGAACGATAATTTACTGCTTTAATGGTAGGTGTTAAAGGAAGATGCAGATCCATCTGGCAGTGAATAACTTACAAAAGAAAATATTTTAATACAAGTATCTGTATGTTCCTTTAAAATGTATTGTAACAGCTAAAACATGTATTTTATTGTGAAAGGTATAACCTTTTAAATCAATTAAGGCAACATTGTAAGAGGTTTATAATATTTTTTTTGTTAATTCTATTGATGTATTTAACTTTTTCCTTACTCGGTTGAATGTTCTATATTTCTGGCTTAAACGTGTAAAAAAAAAAAAAAATCTTGTAAAACTAAACAAAACTCGGATTAAATCATTAAAAAAAAAAAAAAA		Refseq >NM_001087875\|Xenopus laevis mitogen-activated protein kinase 1 (mapk1-b), mRNA GCAGCTCAAGAGAAACTCTCCCGACCGCATTTAATAAAAGCAAAACATGGCAGCGGCAGCGGCCTCGTCTAACCCCGGCGGAGGTCCGGAGATGGTGCGAGGGCAGGCGTTCGACGTAGGCCCGAGATACACCAACCTGTCATATATCGGAGAGGGAGCGTACGGCATGGTGTGTTCTGCCCATTGCAACATTAACAAAGTACGAGTTGCTATCAAGAAAATCAGCCCATTTGAGCATCAGACATACTGCCAGAGAACATTGAGGGAGATCAAAATCTTGCTACGTTTTAAGCATGAAAACATCATTGGAATAAATGACATTATTCGAGCTCCAACCATTGAGCAGATGAAAGATGTGTACATTGTGCAGGACCTCATGGAGACAGATCTCTATAAACTCCTGAAGACTCAGCATCTTAGCAATGACCATATCTGCTATTTCTTGTACCAGATTTTGAGAGGATTAAAGTACATTCATTCAGCCAACGTTCTACATCGTGATCTTAAGCCTTCAAATTTGCTGCTTAATACTACCTGTGATCTCAAGATTTGTGATTTTGGATTGGCTCGTGTTGCAGATCCAGACCATGATCACACTGGCTTTCTCACAGAATATGTAGCCACTCGCTGTTACAGAGCTCCTGAGATCATGCTGAATTCCAAGGGCTATACCAAATCAATTGACATCTGGTCTGTTGGCTGCATTCTCGCTGAGATGCTTTCTAATAGACCAATATTTCCAGGGAAACATTATCTCGACCAACTTAATCACATACTGGGAATTCTTGGATCGCCATCTCAAGAAGACCTAAACTGTATAATCAATTTAAAAGCTAGGAATTACTTGCTTTCCCTTCCTCACAAAAATAAGGTGCCATGGAACCGACTTTTCCCCAATGCAGATCCCAAAGCTCTAGACTTACTGGACAAGATGCTGACATTCAACCCACACAAAAGAATTGAAGTAGAGGCAGCTTTGGCTCATCCTTATCTGGAGCAGTATTATGACCCAAGTGATGAGCCTGTAGCTGAGGCTCCCTTTAAATTTGAAATGGAACTCGATGATTTGCCCAAGGAGACACTGAAGGAGCTAATTTTTGAAGAAACCGCTAGATTCCAGCCAGGGTACTGACCACCATCTTACCACAGGGAAAGGATGTGAAGGACTTTGCACGCTGAGACATCGGTGTTGTTCTTGCCAGTTCTTCCTCCTTGGGCGTGTCCTGTGCTCCATCTCAGCTTGTCCAGTCTATAACTTCTTTGAGCCATTATGGAGGGCACTTCCTGGTAGTTGTGGCTTTTTATGCTTCTGATGAATTCTTTCGATATGGAGAATTGTTCTTGACACTCCTTTGTGAAAGTGGTGCGGCAAACACACACCTGCTGAGACCTTCATTAACCGCTTGTACATTATTATTATTTTTTTTTTTGTATTGTTTTATAAAGATGCAGTGATTTCTTTCCATTTTTCTGGGTATACAGCACCCTGACTTTCACCGGCCCTACACACTGTATCAAACCACACATTCAAACACTGTGGTATTTGGCCTTGGGTTTTTTTTTTCCTTTCTTTGTTCTTTTTTATTTGGGAGAGTTAATTCTCTGGGCACTTTAAATCATTGTAACGCCCTATTTACTTGCACATATCATTTTAAACAAATGCAGTTGTAAGCTTTGAAATTCTAATGGAGCTTTTTATATATATATATATATATATATATATATATATATATATATATATATATATATACAGTTACTAGCTTTCTCTAGCACTTAAGCAGAGCCGAGCAAACTATTTTAACCCTTTCCATGTTTAAGGGACCTTGTAGGTTGGAAAAAAAAAAAAAAAAAAAAAAAA
Protein		Refseq >NP_001017127\|mitogen-activated protein kinase 1 [Xenopus (Silurana) tropicalis] MAAAGASSNPGGGPEMVRGQAFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFKHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADPKALDLLDKMLTFNPHKRIEVEAALAHPYLEQYYDPSDEPVAEAPFKFEMELDDLPKETLKELIFEETARFQPGY	Refseq >NP_001083548\|mitogen-activated protein kinase 1 [Xenopus laevis] MAAAGAASNPGGGPEMVRGQAFDVGPRYINLAYIGEGAYGMVCSAHDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFKHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADPKALDLLDKMLTFNPHKRIEVEAALAHPYLEQYYDPSDEPVAEAPFKFEMELDDLPKETLKELIFEETARFQPGY UniProtKB		Refseq >NP_001081344\|mitogen-activated protein kinase 1 [Xenopus laevis] MAAAAASSNPGGGPEMVRGQAFDVGPRYTNLSYIGEGAYGMVCSAHCNINKVRVAIKKISPFEHQTYCQRTLREIKILLRFKHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRCYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADPKALDLLDKMLTFNPHKRIEVEAALAHPYLEQYYDPSDEPVAEAPFKFEMELDDLPKETLKELIFEETARFQPGY

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis a		laevis b
UniGene		Str.19446	Xl.1680		Xl.874
Unigene EST Profile		EST Profile	EST Profile		EST Profile
GEO data			GEO		GEO
Images		5 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	MAPK1
mouse		MGI	Mapk1	All(12) Targeted, knock Out(5) Targeted, other(6)
zebrafish		ZFIN	mapk1

Publications
First:		Xenopus oocytes and the biochemistry of cell division. [Biochemistry 1990]
Most recent:		WNK4 inhibits Ca(2+)-activated big-conductance potassium channels (BK) via mitogen-activated protein kinase-dependent pathway. [Biochim Biophys Acta 2013]
		View All Papers 32 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		ATP binding MAP kinase activity cAMP-dependent protein kinase activity More[+] cAMP-dependent protein kinase regulator activity protein kinase CK2 activity protein kinase CK2 regulator activity protein kinase activity protein serine/threonine kinase activity protein tyrosine kinase activity
Biological:		protein amino acid phosphorylation
Cellular Component:		cAMP-dependent protein kinase complex protein kinase CK2 complex
EC:		now divided into EC:2.7.11.1, EC:2.7.11.8, EC:2.7.11.9, EC:2.7.11.10, EC:2.7.11.11, EC:2.7.11.12, EC:2.7.11.13, EC:2.7.11.21, EC:2.7.11.22, EC:2.7.11.24, EC:2.7.11.25, EC:2.7.11.30 and EC:2.7.12.1
KOG:		[T] Mitogen-activated protein kinase

Reagents		tropicalis	laevis a		laevis b
Clones		open biosystems	open biosystems		open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes		geneservice/RZPD imagenes
Affymetrix 1.0		Str.19446.1.S1_at [+] Str.19446.1.S3_at Str.19446.1.S2_at Str.46473.1.A1_at Str.47725.1.A1_at	Xl.1680.1.S1_at [+] Xl.24942.1.A1_at Xl.4603.1.S1_at		Xl.874.1.S1_s_at
Affymetrix 2.0			Xl2.1680.1.S1_at		Xl2.874.1.S1_s_at [+] Xl2.874.1.S1_at

Symbol legend[+]