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Summary Expression Gene Literature (699) GO Terms (15) Nucleotides (355) Proteins (22) Interactants (1096) Wiki
XB-GENEPAGE- 479466

Gene Symbol: mapk1

Gene Name: mitogen-activated protein kinase 1

Synonyms: erk , MAP kinase , erk2 , mapk , xp42 , mpk1 , ert1 , mapk2 , p42mapk , prkm1 , prkm2 , mapk1-b , mapk1-a
Add Xenopus synonyms , Nomenclature history


Gene Function: serine/threonine kinase

Protein Function:
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the MAPK/ERK cascade. Depending on the cellular context, this casc...[+]


Interactants: YYY

OMIM Disease Associations:
 
Xenbase Gene ID XB-GENE-479467 XB-GENE-6252586 XB-GENE-865273
Gene Symbol mapk1 mapk1.L mapk1.S
Chromosome scaffold_1 chr1L chr1S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 6.0 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq TrEMBL Refseq TrEMBL Refseq Swiss-Prot TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
GBrowse
tropicalis genome v7.1 gene model
GBrowse
laevis genome v9.1 gene model
GBrowse
laevis genome v9.1 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.19446 Xl.874 Xl.1680
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Images 13 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine mapk1 mapk1.L mapk1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards MAPK1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Mapk1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN mapk1 ZFIN Ensembl
chicken
GEISHA MAPK1 Ensembl
fruit fly
worm
WORMBASE
Publications
First: In vitro effects on microtubule dynamics of purified Xenopus M phase-activated MAP kinase. [Nature 1991]
Most recent: Lineage commitment of embryonic cells involves MEK1-dependent clearance of pluripotency regulator Ventx2. [Elife 2017]
View All Papers 52 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 3 terms 3 terms 15 terms
EC now divided into EC:2.7.11.1, EC:2.7.11.8, EC:2.7.11.9, EC:2.7.11.10, EC:2.7.11.11, EC:2.7.11.12, EC:2.7.11.13, EC:2.7.11.21, EC:2.7.11.22, EC:2.7.11.24, EC:2.7.11.25, EC:2.7.11.30 and EC:2.7.12.1
PANTHER mapk1
KEGG Pathways K04371 K04371 K04371
KOG [T] Mitogen-activated protein kinase
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience Source BioScience
Antibody Mapk1 Ab6 , Mapk1 Ab1 , Mapk1 Ab2 , Mapk1 Ab3 , Mapk1 Ab4 , Mapk1 Ab5 , Mapk1 Ab7 , Mapk1 Ab8 , Mapk1 Ab9 , Mapk1 Ab10 , Mapk Ab5 , Mapk1 Ab13 Mapk1 Ab6 , Mapk1 Ab1 , Mapk1 Ab2 , Mapk1 Ab3 , Mapk1 Ab4 , Mapk1 Ab5 , Mapk1 Ab7 , Mapk1 Ab8 , Mapk1 Ab10 , Mapk Ab5 , Mapk1 Ab13 , Mapk1 Ab16 Mapk1 Ab6 , Mapk1 Ab1 , Mapk1 Ab2 , Mapk1 Ab3 , Mapk1 Ab4 , Mapk1 Ab5 , Mapk1 Ab7 , Mapk1 Ab8 , Mapk1 Ab10 , Mapk Ab5 , Mapk1 Ab13 , Mapk1 Ab16
ORF mapk1 ORF2 mapk1 ORF1
Affymetrix 1.0 Str.19446.1.S1_at [+] Xl.874.1.S1_s_at Xl.1680.1.S1_at [+]
Affymetrix 2.0 Xl2.874.1.S1_s_at [+] Xl2.1680.1.S1_at

Symbol legend[+]

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