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Summary Expression Gene Literature (51) GO Terms (34) Nucleotides (646) Proteins (46) Interactants (1182) Wiki
XB-GENEPAGE-479582
Gene Symbol:
hdac1

Gene Name:
histone deacetylase 1

Synonyms:
HD1 , rpd3 , gon-10 , rpd3l1 , hdac1-a , hdac1-b ( Add synonyms , Nomenclature history )

Gene Function:
regulation of gene expression

Protein Function :
Histone deacetylase that is only required during early steps of development. Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Hist...[+]


InterPro :
His deacetylse 1 , His deacetylse dom , Ureohydrolase dom sf , His deacetylse dom sf [+]

Interactants:
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Diseases: 


External Links:
1/2
 
Xenbase Gene ID XB-GENE-479583 XB-GENE-6252325 XB-GENE-865283
Gene Symbol hdac1 hdac1.L hdac1.S
Chromosome Chr2 chr2L chr2S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 594953
397868
379083
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More.. NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine hdac1 hdac1.L hdac1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards HDAC1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Hdac1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Hdac1 Ensembl
zebrafish
ZFIN, AGR hdac1 ZFIN Ensembl
chicken
GEISHA HDAC1 Ensembl
fruit fly
FLYBASE HDAC1 Ensembl
worm
Publications
First Expression cloning of Siamois, a Xenopus homeobox gene expressed in dorsal-vegetal cells of blastulae and able to induce a complete secondary axis., Cell 1995                
Most Recent Repression of Inappropriate Gene Expression in the Vertebrate Embryonic Ectoderm., Genes (Basel) 2019          
All View All Papers 4 paper(s) referencing morpholinos 4 paper(s) referencing OMIMs 6 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 32 terms 6 terms 6 terms
PANTHER hdac1
KEGG Pathways K06067 K06067 K06067
KOG [B] Histone deacetylase complex, catalytic component RPD3
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks hdac1
Antibodies hdac1 Ab1 hdac1 Ab1 hdac1 Ab1
Morpholinos (on-target & off-target) hdac1 MO1 , hdac1 MO2 hdac1 MO1 , hdac1 MO2 , hdac1 MO3 hdac1 MO1 , hdac1 MO2
ORFs hdac1 ORF1 hdac1.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info