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Summary Expression Gene Literature (86) GO Terms (8) Nucleotides (128) Proteins (28) Interactants (1221) Wiki
XB-GENEPAGE- 479768

Gene Symbol: eomes

Gene Name: eomesodermin

Synonyms: xeomes , eomesodermin
Add Xenopus synonyms , Nomenclature history

Gene Function: T-box transcription factor

Protein Function :
Functions as a transcriptional activator playing a crucial role during development. Functions in gastrulation, regulating mesoderm differentiation. Activates wnt8, t/bra, chrd and mix-A/mix.1 expressio...[+]


Interactants: Loading ...

Disease Ontology:
  

OMIM Diseases:
  
1/2
 

Xenbase Gene ID XB-GENE-479769 XB-GENE-865305 XB-GENE-6487182
Gene Symbol eomes eomes.L eomes.S
Chromosome Chr06 chr6L chr6S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq TrEMBL TrEMBL Refseq Swiss-Prot Refseq TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.45790 [+] Xl.373 Xl.33685 [+]
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 39 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine eomes eomes.L eomes.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen eomes-har204      
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards EOMES OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Eomes MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR ZFIN, AGR eomesa eomesb ZFIN Ensembl
chicken
GEISHA EOMES Ensembl
fruit fly
worm
WORMBASE
Publications
First: The Xenopus T-box gene, Antipodean, encodes a vegetally localised maternal mRNA and can trigger mesoderm formation. [Development 1996]
Most recent: EFhd2/Swiprosin-1 is a common genetic determinator for sensation-seeking/low anxiety and alcohol addiction. [Mol Psychiatry 2018]
View All Papers 22 paper(s) referencing morpholinos 3 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 4 terms 8 terms 4 terms
PANTHER eomes
KEGG Pathways K10173 K10173 K10173
KOG [K] TBX2 and related T-box transcription factors
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones EXRC - 2 clone(s) EXRC - 2 clone(s)  
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience Source BioScience
Antibody Eomes Ab1 Eomes Ab1 Eomes Ab1
Morpholino eomes MO1 , eomes MO2 , eomes MO3 , eomes MO4 eomes MO1 , eomes MO2 , eomes MO3 , eomes MO4 eomes MO1 , eomes MO2 , eomes MO3 , eomes MO4
ORF eomes.L ORF1 eomes.S ORF1
Affymetrix 1.0 Str.45717.1.A1_at [+] Xl.373.1.S1_at
Affymetrix 2.0 Xl2.373.1.S1_at Xl2.33685.1.S1_at [+]

Symbol legend[+]
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Version: 4.9.1
Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556