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Summary Expression Gene Literature (106) GO Terms (24) Nucleotides (144) Proteins (40) Interactants (1399) Wiki
XB-GENEPAGE-479768
Gene Symbol:
eomes

Gene Name:
eomesodermin

Synonyms:
xeomes , eomesodermin , tbr2 ( Add synonyms , Nomenclature history )

Gene Function:
T-box transcription factor

Protein Function :
Functions as a transcriptional activator playing a crucial role during development. Functions in gastrulation, regulating mesoderm differentiation. Activates wnt8, t/bra, chrd and mix-A/mix.1 expressio...[+]


InterPro :
T-box sf , T-box assoc , p53-like TF DNA-bd , TF T-box CS [+]

Interactants:
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Diseases: 


External Links:
1/2
 
Xenbase Gene ID XB-GENE-479769 XB-GENE-865305 XB-GENE-6487182
Gene Symbol eomes eomes.L eomes.S
Chromosome Chr6 chr6L chr6S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100038065
398065
495078
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine eomes eomes.L eomes.S
Phenotype X. tropicalis X. laevis.L X. laevis.S
Smith Morpholino Screen eomes-har204      
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards EOMES OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Eomes MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Eomes Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR eomesa eomesb ZFIN Ensembl
chicken
GEISHA EOMES Ensembl
fruit fly
worm
Publications
First The Xenopus T-box gene, Antipodean, encodes a vegetally localised maternal mRNA and can trigger mesoderm formation., Development 1996        
Most Recent Combinatorial transcription factor activities on open chromatin induce embryonic heterogeneity in vertebrates., EMBO J 2021                          
All View All Papers 22 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 7 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 21 terms 7 terms 4 terms
PANTHER eomes
KEGG Pathways K10173 K10173 K10173
KOG [K] TBX2 and related T-box transcription factors
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks eomes
Mutants Xtr.eomesemHorb
Antibodies Eomes Ab1 , Eomes Ab2 , Eomes Ab3 Eomes Ab1 , Eomes Ab2 , Eomes Ab3 Eomes Ab1 , Eomes Ab2 , Eomes Ab3
Morpholinos (on-target & off-target) eomes MO2 , eomes MO1 , eomes MO3 , eomes MO4 eomes MO1 , eomes MO2 , eomes MO4 , rarb MO2 eomes MO1 , eomes MO4
ORFs eomes.L ORF1 eomes.S ORF1
Clones EXRC Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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