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Summary Expression Gene Literature (205) GO Terms (6) Nucleotides (202) Proteins (37) Interactants (1263) Wiki
XB-GENEPAGE- 479801

Gene Symbol: twist1

Gene Name: twist family bHLH transcription factor 1

Synonyms: Xtwi , X-twi , twist , Xtwist , twist1-b , twist1-a
Add Xenopus synonyms , Nomenclature history

Gene Function: transcription factor

Protein Function :
Probable transcription factor, which may be involved, with other proteins, in establishing the pattern of cell type-specific gene expression in mesodermal cell subgroups.


Interactants: Loading ...

Disease Ontology:
   SAETHRE-CHOTZEN SYNDROME

OMIM Diseases:
   SAETHRE-CHOTZEN SYNDROME; SCS [+]
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Xenbase Gene ID XB-GENE-479802 XB-GENE-6255840 XB-GENE-865309
Gene Symbol twist1 twist1.L twist1.S
Chromosome Chr06 chr6L chr6S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq TrEMBL TrEMBL Refseq TrEMBL Refseq Swiss-Prot TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus PANTHER
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.3251 Xl.23366 Xl.879 [+]
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 198 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine twist1 twist1.L twist1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards TWIST1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Twist1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR ZFIN, AGR twist1a twist1b ZFIN Ensembl
chicken
GEISHA TWIST1 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Facile cruciform formation by an (A-T)34 sequence from a Xenopus globin gene. [J Mol Biol 1985]
Most recent: Ric-8A, a GEF for heterotrimeric G-proteins, controls cranial neural crest cell polarity during migration. [Mech Dev 2018]
View All Papers 61 paper(s) referencing morpholinos 6 paper(s) referencing OMIMs 12 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 1 terms 1 terms 6 terms
PANTHER twist1
KEGG Pathways K09069 K09069 K09069
KOG [K] Transcription factor TWIST
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones EXRC - 7 clone(s)   EXRC - 2 clone(s)
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience Source BioScience
Morpholino twist1 MO1 , twist1 MO2 , twist1 MO3 twist1 MO1 , twist1 MO2 , twist1 MO3 twist1 MO1 , twist1 MO2 , twist1 MO3
ORF twist1 ORF1 twist1.L ORF1 twist1.S ORF1
Affymetrix 1.0 Str.3251.2.S1_a_at Xl.879.1.S1_s_at
Affymetrix 2.0 Xl2.56708.1.S1_at Xl2.879.1.S1_s_at

Symbol legend[+]
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Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556