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Summary Expression Gene Literature (67) GO Terms (7) Nucleotides (102) Proteins (24) Interactants (398) Wiki
XB-GENEPAGE- 479826

Gene Symbol: tal1

Gene Name: T-cell acute lymphocytic leukemia 1

Synonyms: SCL , tal-1 , bHLHa17 , tcl5 , stem cell leukaemia , xscl
Add Xenopus synonyms , Nomenclature history


Gene Function: transcription factor

Protein Function:
Transcription factor that acts synergistically with lmo2 and gata1 to specify embryonic dorsal mesoderm to a hematopoietic fate.


Interactants: Loading ...

OMIM Disease Associations:
1/4
 
Xenbase Gene ID XB-GENE-479827 XB-GENE-17340145 XB-GENE-865312
Gene Symbol tal1 tal1.L tal1.S
Chromosome Chr04 chr4L chr4S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 8.0 JBrowse 8.0 GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq TrEMBL TrEMBL Refseq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.57585 Xl.278
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 47 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine tal1 tal1.L tal1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards TAL1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Tal1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN tal1 ZFIN Ensembl
chicken
GEISHA TAL1 Ensembl
fruit fly
worm
WORMBASE
Publications
First: BMP-like signals are required after the midblastula transition for blood cell development. [Dev Genet 1996]
Most recent: Dissecting BMP signaling input into the gene regulatory networks driving specification of the blood stem cell lineage. [Proc Natl Acad Sci U S A 2017]
View All Papers 25 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs
Functional Ontologies tropicalis laevis.L laevis.S
GO 1 terms 1 terms 7 terms
EC
PANTHER tal1
KEGG Pathways K09068 K09068 K09068
KOG [K] Transcription factor HAND2/Transcription factor TAL1/TAL2/LYL1
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones     EXRC - 2 clone(s)
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Morpholino tal1 MO1 , tal1 MO2 , tal1 MO3 tal1 MO1 , tal1 MO2 , tal1 MO3 tal1 MO1 , tal1 MO2 , tal1 MO3
ORF tal1 ORF1
Affymetrix 1.0 Str.21654.1.S1_at Xl.278.1.S1_at [+]
Affymetrix 2.0 Xl2.278.1.S2_at [+]

Symbol legend[+]

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