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Summary Expression Gene Literature (73) GO Terms (23) Nucleotides (107) Proteins (25) Interactants (523) Wiki
XB-GENEPAGE-479826

Gene Symbol: tal1

Gene Name: T-cell acute lymphocytic leukemia 1

Synonyms: SCL , tal-1 , bHLHa17 , tcl5 , stem cell leukaemia , xscl ( Add Xenopus synonyms , Nomenclature history )

Gene Function: transcription factor

Protein Function :
Transcription factor that acts synergistically with lmo2 and gata1 to specify embryonic dorsal mesoderm to a hematopoietic fate.

Interactants: Loading ...
Disease Ontology:

OMIM Diseases: LEUKEMIA, ACUTE LYMPHOBLASTIC; ALL

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Xenbase Gene ID XB-GENE-479827 XB-GENE-17340145 XB-GENE-865312
Gene Symbol tal1 tal1.L tal1.S
Chromosome Chr04 chr4L chr4S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq TrEMBL TrEMBL TrEMBL Refseq Swiss-Prot Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression
Data Mining tropicalis laevis.L laevis.S
XenMine tal1 tal1.L tal1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards TAL1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Tal1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR tal1 ZFIN Ensembl
chicken
GEISHA TAL1 Ensembl
fruit fly
worm
WORMBASE
Publications
First BMP-like signals are required after the midblastula transition for blood cell development., Dev Genet 1996              
Most Recent Hematopoiesis: from start to immune reconstitution potential., Stem Cell Res Ther null  
All View All Papers 26 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 18 terms 1 terms 7 terms
PANTHER tal1
KEGG Pathways K09068 K09068 K09068
KOG [K] Transcription factor HAND2/Transcription factor TAL1/TAL2/LYL1
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones     EXRC - 2 clone(s)
Dharmacon Dharmacon Dharmacon
Morpholino tal1 MO1 , tal1 MO2 , tal1 MO3 tal1 MO1 , tal1 MO2 , tal1 MO3 tal1 MO1 , tal1 MO2 , tal1 MO3
ORF tal1.S ORF1
Affymetrix 1.0 Str.21654.1.S1_at Xl.278.1.S1_at [+]
Affymetrix 2.0 Xl2.278.1.S2_at [+]

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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Version: 4.11.2


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