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Summary Expression Gene Literature (92) GO Terms (18) Nucleotides (103) Proteins (39) Interactants (519) Wiki
XB-GENEPAGE-479924
Gene Symbol:
slc12a1

Gene Name:
solute carrier family 12 member 1

Synonyms:
XNKCC2 , Na-K-2Cl cotransporter , NKCC2 , NKCC-2 ( Add synonyms , Nomenclature history )

Gene Function:
transmembrane solute exchange

Protein Function :



Interactants:
Loading ...

Diseases: 


Disease Ontology:
Bartter disease type 1

OMIM:
BARTTER SYNDROME, TYPE 1, ANTENATAL; BARTS1

External Links:
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Xenbase Gene ID XB-GENE-479925 XB-GENE-6486739 XB-GENE-17342815
Gene Symbol slc12a1 slc12a1.L slc12a1.S
Chromosome Chr3 chr3L
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2
CDS Gene model Gene model
Entrez Gene 100490198
101101701
mRNA NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein  More.. NCBI Protein NCBI Protein  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine slc12a1 slc12a1.L slc12a1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards SLC12A1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Slc12a1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Slc12a1 Ensembl
zebrafish
frmd4a Ensembl
chicken
GEISHA SLC12A1 Ensembl
fruit fly
worm
Publications
First Isoforms of the Na-K-2Cl cotransporter in murine TAL II. Functional characterization and activation by cAMP., Am J Physiol 1999  
Most Recent SLC12A2 variants cause a neurodevelopmental disorder or cochleovestibular defect., Brain 2020  
All View All Papers 11 paper(s) referencing morpholinos 6 paper(s) referencing OMIMs 8 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 17 terms 3 terms 0 term
PANTHER slc12a1
KEGG Pathways
KOG [P] Na+/K+ symporter
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks slc12a1
Antibodies SLC12A1 Ab1 SLC12A1 Ab1 SLC12A1 Ab1
Clones Horizon Horizon Source BioScience
Plasmids Addgene Addgene

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