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Summary Expression Gene Literature (82) GO Terms (2) Nucleotides (85) Proteins (26) Interactants (328) Wiki
XB-GENEPAGE- 479924

Gene Symbol: slc12a1

Gene Name: solute carrier family 12 member 1

Synonyms: XNKCC2 , Na-K-2Cl cotransporter , NKCC2 , NKCC-2
Add Xenopus synonyms , Nomenclature history


Gene Function: transmembrane solute exchange

Protein Function:


Interactants: Loading ...

OMIM Disease Associations: BARTTER SYNDROME, ANTENATAL, TYPE 1
1/3
 
Xenbase Gene ID XB-GENE-479925 XB-GENE-6486739 XB-GENE-17342815
Gene Symbol slc12a1 slc12a1.L slc12a1.S
Chromosome scaffold_3 chr3L
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 6.0
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide
Protein NCBI Protein TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene [+] Xl.51346 [+]
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 35 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine slc12a1 slc12a1.L slc12a1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards SLC12A1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Slc12a1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
si:ch211-220f12.1 ZFIN Ensembl
chicken
GEISHA SLC12A1 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Isoforms of the Na-K-2Cl cotransporter in murine TAL II. Functional characterization and activation by cAMP. [Am J Physiol 1999]
Most recent: Structure-activity relationships of bumetanide derivatives: correlation between diuretic activity in dogs and inhibition of the human NKCC2A transporter. [Br J Pharmacol 2017]
View All Papers 10 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs
Functional Ontologies tropicalis laevis.L laevis.S
GO 0 term 2 terms 0 term
EC
PANTHER slc12a1
KEGG Pathways
KOG [P] Na+/K+ symporter
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones   EXRC - 1 clone(s)  
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience
Affymetrix 1.0 StrJgi.2821.1.S1_at [+]
Affymetrix 2.0 Xl2.51360.1.S1_at [+]

Symbol legend[+]

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