Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (77) GO Terms (13) Nucleotides (127) Proteins (35) Interactants (272) Wiki
XB-GENEPAGE-480034
Gene Symbol:
slc7a5

Gene Name:
solute carrier family 7 member 5

Synonyms:
L amino acid transporter-1 , LAT-1 , e16 , cd98 , lat1 , 4f2lc , mpe16 , slc7a5-b , slc7a5-a , lat1 ( Add synonyms , Nomenclature history )

Gene Function:
transmembrane solute exchange

Protein Function :


InterPro :
Serpin sf 1 , Serpin B1 , Serpin CS , Serpin fam [+]

Interactants:
Loading ...

Diseases: 


External Links:
1/3
 
Xenbase Gene ID XB-GENE-480035 XB-GENE-6254908 XB-GENE-865334
Gene Symbol slc7a5 slc7a5.L slc7a5.S
Chromosome Chr04 chr4L Scaffold25
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100101781
398978
734908
mRNA RefSeq RefSeq RefSeq
Protein RefSeq RefSeq RefSeq
Genomic
 tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine slc7a5 slc7a5.L slc7a5.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards SLC7A5 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Slc7a5 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Slc7a5 Ensembl
zebrafish
ZFIN, AGR slc7a5 ZFIN Ensembl
chicken
GEISHA SLC7A5 Ensembl
fruit fly
worm
Publications
First A neuronal nicotinic acetylcholine receptor subunit (alpha 7) is developmentally regulated and forms a homo-oligomeric channel blocked by alpha-BTX., Neuron 1990  
Most Recent Xenopus slc7a5 is essential for notochord function and eye development., Mech Dev 2019                  
All View All Papers 2 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 13 terms 4 terms 4 terms
PANTHER slc7a5
KEGG Pathways K13780 K13780 K13780
KOG [E] Amino acid transporters (alt_id KOG:1287)
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks slc7a5
Morpholinos slc7a5 MO1 slc7a5 MO1 slc7a5 MO1
ORFs slc7a5.L ORF1 slc7a5.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
Xenbase: The Xenopus Model Organism Knowledgebase.
Version: 4.14.0
Major funding for Xenbase is provided by grant P41 HD064556