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Summary Expression Gene Literature (73) GO Terms (5) Nucleotides (19955) Proteins (38) Interactants (961) Wiki
XB-GENEPAGE- 480093

Gene Symbol: eef1a1

Gene Name: eukaryotic translation elongation factor 1 alpha 1

Synonyms: EF-1 alpha , eef1a-s , elongation factor-1 alpha , EF1alpha
Add Xenopus synonyms , Nomenclature history

Gene Function: cytoplasmic protein required for protein synthesis

Protein Function:
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.


Interactants: Loading ...

OMIM Disease Associations:
 
Xenbase Gene ID XB-GENE-480094 XB-GENE-17330683 XB-GENE-865341
Gene Symbol eef1a1 eef1a1.L eef1a1.S
Chromosome Chr05 Scaffold28 chr5S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq TrEMBL Refseq Swiss-Prot TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.37180 [+] Xl.17432 [+]
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 10 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine eef1a1 eef1a1.L eef1a1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards EEF1A1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Eef1a1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR eef1a1l1 ZFIN Ensembl
chicken
GEISHA EEF1A1 Ensembl
fruit fly
worm
WORMBASE
Publications
First: 42S p48--the most abundant protein in previtellogenic Xenopus oocytes--resembles elongation factor 1 alpha structurally and functionally. [EMBO J 1987]
Most recent: Pitx1 regulates cement gland development in Xenopus laevis through activation of transcriptional targets and inhibition of BMP signaling. [Dev Biol 2018]
View All Papers 9 paper(s) referencing morpholinos 5 paper(s) referencing OMIMs
Functional Ontologies tropicalis laevis.L laevis.S
GO 5 terms 0 term 4 terms
PANTHER eef1a1
KEGG Pathways K03231 K03231
KOG [J] Translation elongation factor EF-1 alpha/Tu
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones     EXRC - 1 clone(s)
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
ORF eef1a1 ORF2
Affymetrix 1.0 Str.8139.1.S1_x_at [+] Xl.17432.1.S1_at [+]
Affymetrix 2.0 Xl2.46764.1.A1_at [+]

Symbol legend[+]
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