Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (25) GO Terms (6) Nucleotides (97) Proteins (23) Interactants (227) Wiki
XB-GENEPAGE- 480121

Gene Symbol: hand1

Gene Name: heart and neural crest derivatives expressed 1

Synonyms: eHand , hand-1
Add Xenopus synonyms , Nomenclature history


Gene Function: basic helix-loop-helix transcription factor

Protein Function:
Plays an essential role in cardiac morphogenesis.


Interactants: YYY

OMIM Disease Associations:
1/8
 
Xenbase Gene ID XB-GENE-480122 XB-GENE-865344 XB-GENE-17344626
Gene Symbol hand1 hand1.L hand1.S
Chromosome Chr03 chr3L chr3S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 8.0 JBrowse 8.0 GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0 GBrowse 9.1 JBrowse 9.1
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq TrEMBL Refseq Swiss-Prot TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
GBrowse
tropicalis genome v8.0 gene model
GBrowse
laevis genome v9.1 gene model
GBrowse
laevis genome v9.1 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.11172 [+] Xl.1098
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Images 52 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine hand1 hand1.L hand1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards HAND1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Hand1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN
chicken
GEISHA HAND1 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Homeodomain factor Nkx2-5 controls left/right asymmetric expression of bHLH gene eHand during murine heart development. [Genes Dev 1997]
Most recent: Asymmetrically reduced expression of hand1 homeologs involving a single nucleotide substitution in a cis-regulatory element. [Dev Biol 2017]
View All Papers 4 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 1 terms 6 terms 0 term
EC
PANTHER hand1
KEGG Pathways K09071 K09071
KOG [K] Transcription factor HAND2/Transcription factor TAL1/TAL2/LYL1
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Affymetrix 1.0 Str.11172.1.S1_at Xl.1098.1.S1_at [+]
Affymetrix 2.0 Xl2.1098.1.S1_at [+]

Symbol legend[+]

My Xenbase: [ Log-in / Register ]
version: [4.5.0]

Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556