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Summary Expression Gene Literature (71) GO Terms (12) Nucleotides (14) Proteins (10) Interactants (433) Wiki
XB-GENEPAGE-480238
Gene Symbol: igf1

Gene Name: insulin like growth factor 1

Synonyms: IGF-I , Somatomedin , xigf1 , igf-1 , somatomedin-C ( Add synonyms , Nomenclature history )

Gene Function: growth factor

Protein Function :
The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. Promotes head development by inhibiting Wnt...[+]

Interactants: Loading ...
OMIM Diseases: INSULIN-LIKE GROWTH FACTOR I DEFICIENCY

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Xenbase Gene ID XB-GENE-480239 XB-GENE-6252361 XB-GENE-17330790
Gene Symbol igf1 igf1.L igf1.S
Chromosome Chr03 chr3L chr3S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene: 100486334
Entrez Gene: 108711020
Entrez Gene: 108712492
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein TrEMBL NCBI Protein Swiss-Prot TrEMBL NCBI Protein Swiss-Prot TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression
Data Mining tropicalis laevis.L laevis.S
XenMine igf1 igf1.L igf1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards IGF1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Igf1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR igf1 ZFIN Ensembl
chicken
GEISHA IGF1 Ensembl
fruit fly
worm
WORMBASE
Publications
First Nucleotide sequence and expression of a cDNA clone encoding a fetal rat binding protein for insulin-like growth factors., J Biol Chem 1989  
Most Recent Transcriptome profiling reveals male- and female-specific gene expression pattern and novel gene candidates for the control of sex determination and gonad development in Xenopus laevis., Dev Genes Evol 2019          
All View All Papers 7 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 6 terms 9 terms 3 terms
PANTHER igf1
KEGG Pathways K05459 K05459 K05459
KOG
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Dharmacon Dharmacon
Affymetrix 1.0 StrEns.5158.1.S1_at Xl.23602.1.S1_at
Affymetrix 2.0 Xl2.23602.1.S1_at

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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