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Summary Expression Gene Literature (117) GO Terms (41) Nucleotides (96) Proteins (40) Interactants (1048) Wiki
XB-GENEPAGE-480303
Gene Symbol:
sox10

Gene Name:
SRY-box 10

Synonyms:
( Add synonyms , Nomenclature history )

Gene Function:
HMG-box transcription factor

Protein Function :
Acts early in neural crest formation, functioning redundantly with the other group E Sox factors sox8 and sox9 to induce neural crest progenitors. Acts downstream of wnt-signaling at the neural plate b...[+]



Interactants:
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Diseases: 


Disease Ontology:
PCWH syndrome [+]

OMIM:
PERIPHERAL DEMYELINATING NEUROPATHY, CENTRAL DYSMYELINATION, WAARDENBURG SYNDROM [+]

External Links:
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Xenbase Gene ID XB-GENE-480304 XB-GENE-865362 XB-GENE-17343488
Gene Symbol sox10 sox10.L sox10.S
Chromosome Chr04 chr4L chr4S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100101700
398422
108715787
mRNA RefSeq RefSeq NCBI Nucleotide
Protein RefSeq Swiss-Prot RefSeq Swiss-Prot Swiss-Prot NCBI Protein
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining tropicalis laevis.L laevis.S
XenMine sox10 sox10.L sox10.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards SOX10 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Sox10 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Sox10 Ensembl
zebrafish
ZFIN, AGR sox10 ZFIN Ensembl
chicken
GEISHA SOX10 Ensembl
fruit fly
worm
Publications
First Hes6 acts in a positive feedback loop with the neurogenins to promote neuronal differentiation., Development 2000                
Most Recent The transcription factor Hypermethylated in Cancer 1 (Hic1) regulates neural crest migration via interaction with Wnt signaling., Dev Biol 2020  
All View All Papers 39 paper(s) referencing morpholinos 9 paper(s) referencing OMIMs 11 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 41 terms 12 terms 2 terms
PANTHER sox10
KEGG Pathways K09270 K09270 K09270
KOG [K] HMG-box transcription factor
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks sox10
Mutants Xla.sox10emHorb
Morpholinos sox10 MO1 sox10 MO1 sox10 MO1
Clones EXRC Horizon Source BioScience Horizon Source BioScience Horizon

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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