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Summary Expression Gene Literature (116) GO Terms (41) Nucleotides (96) Proteins (40) Interactants (1045) Wiki
XB-GENEPAGE-480303
Gene Symbol: sox10

Gene Name: SRY-box 10

Synonyms: ( Add synonyms , Nomenclature history )

Gene Function: HMG-box transcription factor

Protein Function :
Acts early in neural crest formation, functioning redundantly with the other group E Sox factors sox8 and sox9 to induce neural crest progenitors. Acts downstream of wnt-signaling at the neural plate b...[+]

Interactants: Loading ...
Diseases:  Disease Ontology: PCWH syndrome [+]

OMIM: PERIPHERAL DEMYELINATING NEUROPATHY, CENTRAL DYSMYELINATION, WAARDENBURG SYNDROM [+]

External Disease Links: ClinVar, MalaCards, KEGG Disease, DECIPHER
1/5
 
Xenbase Gene ID XB-GENE-480304 XB-GENE-865362 XB-GENE-17343488
Gene Symbol sox10 sox10.L sox10.S
Chromosome Chr04 chr4L chr4S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100101700
398422
108715787
mRNA RefSeq RefSeq NCBI Nucleotide
Protein RefSeq Swiss-Prot RefSeq TrEMBL TrEMBL Swiss-Prot Swiss-Prot NCBI Protein TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining tropicalis laevis.L laevis.S
XenMine sox10 sox10.L sox10.S
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards SOX10 OMIM Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Sox10 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR sox10 ZFIN Ensembl
chicken
GEISHA SOX10 Ensembl
fruit fly
worm
WORMBASE
Publications
First Hes6 acts in a positive feedback loop with the neurogenins to promote neuronal differentiation., Development 2000                
Most Recent Heparan sulfate proteoglycans regulate BMP signalling during neural crest induction., Dev Biol 2020          
All View All Papers 39 paper(s) referencing morpholinos 8 paper(s) referencing OMIMs 10 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 41 terms 12 terms 2 terms
PANTHER sox10
KEGG Pathways K09270 K09270 K09270
KOG [K] HMG-box transcription factor
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks sox10
Mutants Xla.sox10emHorb
Morpholinos sox10 MO1 sox10 MO1 sox10 MO1
Clones EXRC Horizon Source BioScience Horizon Source BioScience Horizon

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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