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Summary Expression Gene Literature (20) GO Terms (10) Nucleotides (178) Proteins (49) Interactants (1096) Wiki
XB-GENEPAGE-480378
Gene Symbol:
fzd10

Gene Name:
frizzled class receptor 10

Synonyms:
Fz-10 , Xfz10 , frizzled-10 , frizzled10 , fz10 , Xfr9 , fzd10-a , fzd10-b ( Add synonyms , Nomenclature history )

Gene Function:
transmembrane receptor in the wnt signaling pathway

Protein Function :
Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nucl...[+]



Interactants:
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Diseases: 


External Links:
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Xenbase Gene ID XB-GENE-480379 XB-GENE-865370 XB-GENE-6253606
Gene Symbol fzd10 fzd10.L fzd10.S
Chromosome Chr1 chr1L chr1S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 448162
387604
387605
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine fzd10 fzd10.L fzd10.S
Phenotype X. tropicalis X. laevis.L X. laevis.S
Smith Morpholino Screen tgas025k08      
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards FZD10 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Fzd10 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Fzd10 Ensembl
zebrafish
ZFIN, AGR fzd10 ZFIN Ensembl
chicken
GEISHA FZD10 Ensembl
fruit fly
worm
Publications
First Two novel Xenopus frizzled genes expressed in developing heart and brain., Mech Dev 1999      
Most Recent TMEM79/MATTRIN defines a pathway for Frizzled regulation and is required for Xenopus embryogenesis., Elife 2020                                                                                            
All View All Papers 3 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 9 terms 5 terms 6 terms
PANTHER fzd10
KEGG Pathways K02842 K02842 K02842
KOG [T] Smoothened and related G-protein-coupled receptors
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks fzd10
Morpholinos (on-target & off-target) fzd10 MO2 , fzd10 MO3 fzd10 MO1
ORFs fzd10.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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