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Summary Expression Gene Literature (86) GO Terms (0) Nucleotides (218) Proteins (31) Interactants (897) Wiki
XB-GENEPAGE-480430

Gene Symbol: zic3

Gene Name: Zic family member 3

Synonyms: Zinc finger protein of the cerebellum 3 , xzic3 ( Add synonyms , Nomenclature history )

Gene Function: zinc finger, C2H2 type

Protein Function :
Probably acts as a transcriptional activator. May bind to the minimal GLI-consensus sequence 5'-GGGTGGTC-3'. Can determine the ectodermal cell fate and promote the earliest step of neural and neural cr...[+]

Interactants: Loading ...
Disease Ontology: visceral heterotaxy

OMIM Diseases: HETEROTAXY, VISCERAL, 1, X-LINKED; HTX1 [+]

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Xenbase Gene ID XB-GENE-480431 XB-GENE-17335097 XB-GENE-865376
Gene Symbol zic3 zic3.L zic3.S
Chromosome Chr08 chr8L chr8S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
mRNA RefSeq RefSeq
Protein RefSeq Swiss-Prot RefSeq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression
Data Mining tropicalis laevis.L laevis.S
XenMine zic3 zic3.L zic3.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards ZIC3 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Zic3 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR zic3 ZFIN Ensembl
chicken
GEISHA ZIC3 Ensembl
fruit fly
worm
WORMBASE
Publications
First Xenopus Zic3, a primary regulator both in neural and neural crest development., Proc Natl Acad Sci U S A 1997              
Most Recent Xenbase: Facilitating the Use of Xenopus to Model Human Disease., Front Physiol 2019            
All View All Papers 21 paper(s) referencing morpholinos 6 paper(s) referencing OMIMs 7 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 0 term 0 term 0 term
PANTHER zic3
KEGG Pathways K18487 K18487
KOG [R] FOG: Zn-finger
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Dharmacon Dharmacon Dharmacon
Morpholino zic3 MO1 , zic3 MO2 , zic3 MO3 , zic3 MO4 , zic3 MO5 zic3 MO1 , zic3 MO2 , zic3 MO3 , zic3 MO4 , zic3 MO5 zic3 MO1 , zic3 MO2 , zic3 MO3 , zic3 MO4 , zic3 MO5
ORF zic3 ORF1 zic3.S ORF1
Affymetrix 1.0 Str.10234.1.S2_at [+] Xl.7969.1.S1_at
Affymetrix 2.0 Xl2.7969.1.S1_at [+]

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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