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Summary Expression Gene Literature (88) GO Terms (17) Nucleotides (232) Proteins (49) Interactants (916) Wiki
XB-GENEPAGE-480430
Gene Symbol:
zic3

Gene Name:
Zic family member 3

Synonyms:
Zinc finger protein of the cerebellum 3 , xzic3 ( Add synonyms , Nomenclature history )

Gene Function:
zinc finger, C2H2 type

Protein Function :
Probably acts as a transcriptional activator. May bind to the minimal GLI-consensus sequence 5'-GGGTGGTC-3'. Can determine the ectodermal cell fate and promote the earliest step of neural and neural cr...[+]



Interactants:
Loading ...

Diseases: 


Disease Ontology:
visceral heterotaxy [+]

OMIM:
HETEROTAXY, VISCERAL, 1, X-LINKED; HTX1 [+]

External Links:
1/5
 
Xenbase Gene ID XB-GENE-480431 XB-GENE-17335097 XB-GENE-865376
Gene Symbol zic3 zic3.L zic3.S
Chromosome Chr08 chr8L chr8S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 448197
108698501
394375
mRNA RefSeq NCBI Nucleotide RefSeq
Protein RefSeq Swiss-Prot NCBI Protein RefSeq Swiss-Prot Swiss-Prot Swiss-Prot Swiss-Prot Swiss-Prot Swiss-Prot
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining tropicalis laevis.L laevis.S
XenMine zic3 zic3.L zic3.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards ZIC3 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Zic3 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Zic3 Ensembl
zebrafish
ZFIN, AGR zic3 ZFIN Ensembl
chicken
GEISHA ZIC3 Ensembl
fruit fly
worm
Publications
First Xenopus Zic3, a primary regulator both in neural and neural crest development., Proc Natl Acad Sci U S A 1997              
Most Recent Natural size variation among embryos leads to the corresponding scaling in gene expression., Dev Biol 2020                      
All View All Papers 21 paper(s) referencing morpholinos 6 paper(s) referencing OMIMs 7 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 15 terms 1 terms 11 terms
PANTHER zic3
KEGG Pathways K18487 K18487 K18487
KOG [R] FOG: Zn-finger
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks zic3
Morpholinos zic3 MO1 , zic3 MO2 , zic3 MO3 , zic3 MO4 , zic3 MO5 zic3 MO1 , zic3 MO2 , zic3 MO3 , zic3 MO4 , zic3 MO5 zic3 MO1 , zic3 MO2 , zic3 MO3 , zic3 MO4 , zic3 MO5
ORFs zic3 ORF1 zic3.S ORF1
Clones Horizon Source BioScience Horizon Horizon Source BioScience

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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