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Summary Expression Gene Literature (10) GO Terms (16) Nucleotides (41) Proteins (26) Interactants (215) Wiki
XB-GENEPAGE-480440
Gene Symbol:
dkk2

Gene Name:
dickkopf WNT signaling pathway inhibitor 2

Synonyms:
dickkopf2 , dickkopf 2 , dkk-2 ( Add synonyms , Nomenclature history )

Gene Function:
secreted protein, negative regulator of wnt receptor signaling pathway

Protein Function :



Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-480441 XB-GENE-865377 XB-GENE-17343796
Gene Symbol dkk2 dkk2.L dkk2.S
Chromosome Chr01 chr1L chr1S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100493182
378632
108706725
mRNA NCBI Nucleotide RefSeq NCBI Nucleotide
Protein NCBI Protein RefSeq NCBI Protein
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining tropicalis laevis.L laevis.S
XenMine dkk2 dkk2.L dkk2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards DKK2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Dkk2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Dkk2 Ensembl
zebrafish
ZFIN, AGR dkk2 ZFIN Ensembl
chicken
GEISHA DKK2 Ensembl
fruit fly
worm
Publications
First Mutual antagonism between dickkopf1 and dickkopf2 regulates Wnt/beta-catenin signalling., Curr Biol 2000          
Most Recent Dkk2 promotes neural crest specification by activating Wnt/β-catenin signaling in a GSK3β independent manner., Elife 2018                        
All View All Papers 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 16 terms 3 terms 3 terms
PANTHER dkk2
KEGG Pathways K02165 K02165 K02165
KOG [T] Proteins containing Ca2+-binding EGF-like domains
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks dkk2
Morpholinos dkk2 MO1 , dkk2 MO2 dkk2 MO1 , dkk2 MO2 dkk2 MO1 , dkk2 MO2
Clones Horizon Horizon Source BioScience Horizon

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