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Summary Expression Gene Literature (12) GO Terms (5) Nucleotides (26) Proteins (15) Interactants (190) Wiki
XB-GENEPAGE- 480440

Gene Symbol: dkk2

Gene Name: dickkopf WNT signaling pathway inhibitor 2

Synonyms: dickkopf2 , dickkopf 2 , dkk-2
Add Xenopus synonyms , Nomenclature history


Gene Function: secreted protein, negative regulator of wnt receptor signaling pathway

Protein Function :


Interactants: Loading ...

Disease Ontology:
  

OMIM Diseases:
  
 

Xenbase Gene ID XB-GENE-480441 XB-GENE-865377 XB-GENE-17343796
Gene Symbol dkk2 dkk2.L dkk2.S
Chromosome Chr01 chr1L chr1S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide Refseq
Protein NCBI Protein TrEMBL Refseq TrEMBL TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus PANTHER
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Xl.552
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 3 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine dkk2 dkk2.L dkk2.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards DKK2 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Dkk2 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR dkk2 ZFIN Ensembl
chicken
GEISHA DKK2 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Dickkopf genes are co-ordinately expressed in mesodermal lineages. [Mech Dev 1999]
Most recent: Dkk2 promotes neural crest specification by activating Wnt/β-catenin signaling in a GSK3β independent manner. [Elife 2018]
View All Papers 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 4 terms 3 terms 3 terms
PANTHER dkk2
KEGG Pathways K02165 K02165 K02165
KOG [T] Proteins containing Ca2+-binding EGF-like domains
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience
Morpholino dkk2 MO1 , dkk2 MO2 dkk2 MO1 , dkk2 MO2 dkk2 MO1 , dkk2 MO2
Affymetrix 1.0 StrEns.8046.1.S1_at Xl.552.1.S1_at
Affymetrix 2.0 Xl2.552.1.S1_at

Symbol legend[+]
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