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Summary Expression Gene Literature (10) GO Terms (9) Nucleotides (27) Proteins (18) Interactants (214) Wiki
XB-GENEPAGE-480440
Gene Symbol: dkk2

Gene Name: dickkopf WNT signaling pathway inhibitor 2

Synonyms: dickkopf2 , dickkopf 2 , dkk-2 ( Add synonyms , Nomenclature history )

Gene Function: secreted protein, negative regulator of wnt receptor signaling pathway

Protein Function :


Interactants: Loading ...
 
Xenbase Gene ID XB-GENE-480441 XB-GENE-865377 XB-GENE-17343796
Gene Symbol dkk2 dkk2.L dkk2.S
Chromosome Chr01 chr1L chr1S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.1 Version 9.1
CDS Gene model
Entrez Gene: 100493182
Entrez Gene: 378632
Entrez Gene: 108706725
mRNA NCBI Nucleotide RefSeq NCBI Nucleotide
Protein NCBI Protein TrEMBL RefSeq TrEMBL NCBI Protein TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression
Data Mining tropicalis laevis.L laevis.S
XenMine dkk2 dkk2.L dkk2.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards DKK2 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Dkk2 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR dkk2 ZFIN Ensembl
chicken
GEISHA DKK2 Ensembl
fruit fly
worm
WORMBASE
Publications
First Mutual antagonism between dickkopf1 and dickkopf2 regulates Wnt/beta-catenin signalling., Curr Biol 2000          
Most Recent Dkk2 promotes neural crest specification by activating Wnt/β-catenin signaling in a GSK3β independent manner., Elife 2018                        
All View All Papers 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 9 terms 3 terms 3 terms
PANTHER dkk2
KEGG Pathways K02165 K02165 K02165
KOG [T] Proteins containing Ca2+-binding EGF-like domains
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Horizon Horizon Horizon
Morpholino dkk2 MO1 , dkk2 MO2 dkk2 MO1 , dkk2 MO2 dkk2 MO1 , dkk2 MO2
Affymetrix 1.0 StrEns.8046.1.S1_at Xl.552.1.S1_at
Affymetrix 2.0 Xl2.552.1.S1_at

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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