Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (66) GO Terms (17) Nucleotides (123) Proteins (44) Interactants (833) Wiki
XB-GENEPAGE-480475
Gene Symbol:
foxa2

Gene Name:
forkhead box A2

Synonyms:
hnf3b , hnf3beta , hnf3-beta , HNF-3B ( Add synonyms , Nomenclature history )

Gene Function:
forkhead domain transcription factor

Protein Function :
Acts as a transcriptional activator during early development, limiting the extent of mesoderm formation in the gastrula. Binds to DNA via the target sequence 5'-GT[AC]AACA-3', with 5'-GTAAACA-3' being ...[+]


InterPro :
TF fork head CS 2 , Forkhead box C , Fork-head N , WH DNA-bd sf [+]

Interactants:
Loading ...

Diseases: 


External Links:
1/3
 
Xenbase Gene ID XB-GENE-480476 XB-GENE-865381 XB-GENE-17336344
Gene Symbol foxa2 foxa2.L foxa2.S
Chromosome Chr05 chr5L chr5S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.1
CDS Gene model Gene model
Entrez Gene 395063
100127318
mRNA RefSeq RefSeq
Protein RefSeq Swiss-Prot Swiss-Prot RefSeq Swiss-Prot
Genomic
 tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining tropicalis laevis.L laevis.S
XenMine foxa2 foxa2.L foxa2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards FOXA2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Foxa2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Foxa2 Ensembl
zebrafish
ZFIN, AGR foxa2 ZFIN Ensembl
chicken
GEISHA FOXA2 Ensembl
fruit fly
worm
Publications
First Sequential expression of HNF-3 beta and HNF-3 alpha by embryonic organizing centers: the dorsal lip/node, notochord and floor plate., Mech Dev 1993                  
Most Recent Endosome-Mediated Epithelial Remodeling Downstream of Hedgehog-Gli Is Required for Tracheoesophageal Separation., Dev Cell 2019  
All View All Papers 12 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 5 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 17 terms 7 terms 0 term
PANTHER foxa2
KEGG Pathways K08035 K08035
KOG [K] Forkhead/HNF-3-related transcription factor (alt_id KOG:3563)
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks foxa2
Antibodies Foxa2 Ab1 , Foxa2 Ab2 Foxa2 Ab1 , Foxa2 Ab2 Foxa2 Ab1 , Foxa2 Ab2
Clones Horizon Source BioScience Horizon

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
Xenbase: The Xenopus Model Organism Knowledgebase.
Version: 4.14.0
Major funding for Xenbase is provided by grant P41 HD064556