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Summary Expression Gene Literature (70) GO Terms (18) Nucleotides (125) Proteins (45) Interactants (872) Wiki
XB-GENEPAGE-480475
Gene Symbol:
foxa2

Gene Name:
forkhead box A2

Synonyms:
hnf3b , hnf3beta , hnf3-beta , HNF-3B ( Add synonyms , Nomenclature history )

Gene Function:
forkhead domain transcription factor

Protein Function :
Acts as a transcriptional activator during early development, limiting the extent of mesoderm formation in the gastrula. Binds to DNA via the target sequence 5'-GT[AC]AACA-3', with 5'-GTAAACA-3' being ...[+]


InterPro :
TF fork head CS 2 , Forkhead box C , Fork-head N , WH DNA-bd sf [+]

Interactants:
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Diseases: 


External Links:
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Xenbase Gene ID XB-GENE-480476 XB-GENE-865381 XB-GENE-17336344
Gene Symbol foxa2 foxa2.L foxa2.S
Chromosome Chr5 chr5L chr5S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model
Entrez Gene 395063
100127318
mRNA RefSeq NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine foxa2 foxa2.L foxa2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards FOXA2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Foxa2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Foxa2 Ensembl
zebrafish
ZFIN, AGR foxa2 ZFIN Ensembl
chicken
GEISHA FOXA2 Ensembl
fruit fly
Publications
First Sequential expression of HNF-3 beta and HNF-3 alpha by embryonic organizing centers: the dorsal lip/node, notochord and floor plate., Mech Dev 1993                  
Most Recent Xenopus leads the way: Frogs as a pioneering model to understand the human brain., Genesis 2021            
All View All Papers 12 paper(s) referencing morpholinos 3 paper(s) referencing OMIMs 8 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 18 terms 7 terms 0 term
PANTHER foxa2
KEGG Pathways K08035 K08035
KOG [K] Forkhead/HNF-3-related transcription factor (alt_id KOG:3563)
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks foxa2
Antibodies Foxa2 Ab1 , Foxa2 Ab2 Foxa2 Ab1 , Foxa2 Ab2 Foxa2 Ab1 , Foxa2 Ab2
Clones Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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