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XB-GENEPAGE-480485
Gene Symbol:
irx3
Gene Name: iroquois homeobox 3
Synonyms:
xiro3
,
mgc131103
,
xiro-3
,
irx3b
( Gene Function: homeodomain transcription factor Protein Function
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Acts partially redundantly with other irx members in neural patterning. Required for formation of the posterior forebrain, midbrain, hindbrain, and to a lesser extent, spinal cord. Both up-regulates an...[+]
Interactants:
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Diseases: External Links:
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Xenbase Gene ID | XB-GENE-480486 | XB-GENE-480490 | XB-GENE-17335664 | |||||
Gene Symbol | irx3 | irx3.L | irx3.S | Chromosome | Chr4 | chr4L | chr4S | |
Molecules | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genomic Sequence |
Version 10.0
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Version 9.1
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Version 9.1
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CDS |
Gene model
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Gene model
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Gene model
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Entrez Gene |
407888
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399365
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108715336
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mRNA |
RefSeq
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NCBI Nucleotide
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NCBI Nucleotide
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Protein
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Genomic |
X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genome Browser (Click image to open in Genome Browser) |
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Genomic Synteny | Genomicus PANTHER | |||||||
Expression | Development Stages | Embryonic Tissues | Adult Tissues | |||||
Summary for |
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More Information |
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Data Mining | X. tropicalis | X. laevis.L | X. laevis.S | |||||
XenMine | irx3 | irx3.L | irx3.S | |||||
Orthology |
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mouse |
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rat |
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zebrafish |
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chicken |
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fruit fly |
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worm |
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Publications | ||||||||
First |
Xiro3 encodes a Xenopus homolog of the Drosophila Iroquois genes and functions in neural specification., EMBO J 1998 ![]() |
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Most Recent |
Sox17 and β-catenin co-occupy Wnt-responsive enhancers to govern the endoderm gene regulatory network., Elife 2020 ![]() |
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All | View All Papers 9 paper(s) referencing morpholinos 4 paper(s) referencing OMIMs | |||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||
GO | 19 terms | 24 terms | 7 terms | |||||
PANTHER | irx3 | |||||||
KEGG Pathways | ||||||||
KOG |
[K] Transcription factor MEIS1 and related HOX domain proteins
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Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||
CRISPRscan Tracks | irx3 | |||||||
Morpholinos | irx3 MO1 , irx3 MO2 , irx3 MO3 | irx3 MO1 , irx3 MO2 , irx3 MO3 | irx3 MO1 , irx3 MO2 , irx3 MO3 | |||||
ORFs | irx3 ORF1 | irx3.L ORF1 | ||||||
Clones | EXRC Horizon Source BioScience | Horizon Source BioScience | Horizon | |||||
Plasmids | Addgene | Addgene |
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