Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (141) GO Terms (12) Nucleotides (29) Proteins (20) Interactants (958) Wiki
XB-GENEPAGE-480495
Gene Symbol: fgf4

Gene Name: fibroblast growth factor 4 (heparin secretory transforming protein 1, Kaposi sarcoma oncogene)

Synonyms: efgf , HBGF-4 , XEFGF , fgfe , fgf-4 , Xfgf4 , Xfgf-4 , fgf4-b , fgf4-a ( Add synonyms , Nomenclature history )

Gene Function: heparin-binding growth factor

Protein Function :
Plays an important role in the regulation of embryonic development, cell proliferation, and cell differentiation. Good candidate for an inducing factor with possible roles both in mesoderm induction at...[+]


Interactants: Loading ...
1/5
 
Xenbase Gene ID XB-GENE-480496 XB-GENE-6252641 XB-GENE-865382
Gene Symbol fgf4 fgf4.L fgf4.S
Chromosome Chr04 chr4L chr4S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene: 100217325
Entrez Gene: 378586
Entrez Gene: 378587
mRNA RefSeq RefSeq RefSeq
Protein RefSeq TrEMBL TrEMBL TrEMBL RefSeq Swiss-Prot RefSeq TrEMBL Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression
Data Mining tropicalis laevis.L laevis.S
XenMine fgf4 fgf4.L fgf4.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards FGF4 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Fgf4 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR fgf4 ZFIN Ensembl
chicken
GEISHA FGF4 Ensembl
fruit fly
worm
WORMBASE
Publications
First Mesoderm-inducing properties of INT-2 and kFGF: two oncogene-encoded growth factors related to FGF., Development 1989  
Most Recent Cdc2-like kinase 2 (Clk2) promotes early neural development in Xenopus embryos., Dev Growth Differ 2019                                
All View All Papers 28 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 8 terms 7 terms 7 terms
PANTHER fgf4
KEGG Pathways K04358 K04358 K04358
KOG [T] Fibroblast growth factor
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Horizon Horizon Horizon
Morpholino fgf4 MO1 fgf4 MO1 fgf4 MO1
Affymetrix 1.0 StrEns.2552.1.S1_at Xl.1180.1.S1_at Xl.1181.1.S1_at
Affymetrix 2.0 Xl2.1180.1.S1_at Xl2.1181.1.S1_at

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
Xenbase: The Xenopus laevis and X. tropicalis resource.
Version: 4.12.2


Major funding for Xenbase is provided by grant P41 HD064556