Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (24) GO Terms (11) Nucleotides (161) Proteins (44) Interactants (369) Wiki
XB-GENEPAGE-480578
Gene Symbol:
spry1

Gene Name:
sprouty RTK signaling antagonist 1

Synonyms:
sprouty , sprouty1 , sprouty-1 , sprouty 1 , Xtsprouty1 , xspry1 , spry1-a , spry1-b ( Add synonyms , Nomenclature history )

Gene Function:
regulation of signal transduction

Protein Function :


InterPro :
TPR-like helical dom sf , TPR-contain dom , TPR repeat , SPRY1 [+]

Interactants:
Loading ...

Diseases: 


External Links:
1/6
 
Xenbase Gene ID XB-GENE-480579 XB-GENE-6007713 XB-GENE-6372210
Gene Symbol spry1 spry1.L spry1.S
Chromosome Chr01 chr1L chr1S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 449470
100192368
100294515
mRNA RefSeq RefSeq RefSeq
Protein RefSeq RefSeq RefSeq
Genomic
 tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining tropicalis laevis.L laevis.S
XenMine spry1 spry1.L spry1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards SPRY1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Spry1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Spry1 Ensembl
zebrafish
spry1 Ensembl
chicken
GEISHA SPRY1 Ensembl
fruit fly
worm
Publications
First naked cuticle encodes an inducible antagonist of Wnt signalling., Nature 2000  
Most Recent The Expression of Key Guidance Genes at a Forebrain Axon Turning Point Is Maintained by Distinct Fgfr Isoforms but a Common Downstream Signal Transduction Mechanism., eNeuro 2019                    
All View All Papers 2 paper(s) referencing morpholinos 1 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 11 terms 6 terms 6 terms
PANTHER spry1
KEGG Pathways K04704 K04704 K04704
KOG [T] Signal transduction protein Enabled, contains WH1 domain
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks spry1
Morpholinos spry1 MO1 , spry1 MO2 spry1 MO1 , spry1 MO2 spry1 MO1 , spry1 MO2
ORFs spry1 ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
Xenbase: The Xenopus Model Organism Knowledgebase.
Version: 4.14.0
Major funding for Xenbase is provided by grant P41 HD064556