chrd Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (376)

Nucleotides (603)

Interactants (727)

XB-GENEPAGE-480637

Gene Symbol: chrd Gene Name: chordin Synonyms: chd, chordin, X-chordin Add Xenopus synonyms Gene Function: extracellular BMP antagonist, dorsalizing factor Interactants: bmp4(124) , t(120) , gsc(107) , nog(97) , wnt8a(70) , otx2(63) , sox2(59) View All	1/6

XB-GENE-480638

XB-GENE-865395

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001142657\|Xenopus (Silurana) tropicalis chordin (chrd), mRNA GGACACTGGACAGAACTGTCCCCTCCGGACATTGATACCTGCTGTGCAGAAGTGACTGGTCCGGATAGCAGAGAGCGCTCTATTCACTACTGGAGTGTGTGTGGCGCAGTGTTGCCTGTTGGCACAAGGGAAGGGTACATAACACATGTACCGGGGATGTGACCCAGAGAGCCAGAGACAAGTAACATAGTTTGCTGGGTATAGTGCAGGGCATATACACTAAACGGTCACTATACAATCCTCAACTCTTTGGACTCACTGAGCTTGCTCGGGGCTACCACAAAAATGCTTTGTTCCCCCATCTTACTTCTGTGGACCCTGTGGATTATGGCTGTGGATTGCTCTCGCCCAAAGGTTTTCCTGCCCATTCAGCCTGAACAGGAGCCCCTCCAATCTAAGACACCAGCAGGTTGTACGTTTGGTGGAAAATTTTACTCTCTGGAGGATTCATGGCATCCAGATCTTGGGGATCCATTCGGAGTTATGCACTGTGTATTATGCTATTGTGAGCCGCAGCGAAGTCGCCGGGGAAAACCATCTGGCAAAGTCAGCTGCAAAAACATCAAACATGATTGCCCCTCACCCTCCTGTTCTAACCCTGTCCTGCTTTCTGGACATTGCTGCAAGACTTGTCCCAAAGCTCCTCCTCCTCCTATAAAGAAATCAGACTTTGTTTTTGATGGATTCGAGTATTTTCATGGGAAGGATGATGATCTTTATAATGATCGCTCTTACCTTAGTTCTGATGATGTCACTGTGGAGGAGAATCGTTCAGAATATGTTGCATTATTAACAGCACCCAGCCACGTGTGGCCCCCAGTTACCAGTGGAGTAGCCAAGGCTCGATTCAATCTGCAGCGCTCCAGTTTGCTCTTCTCAATCACCTATAAATGGATAGACAGACTTTCCCGAATCCGCTTCTCCGATCTTGAAGGTTCTGTGCTGTTTGAACACCCAGTGCACAGAATGGGATCCCCACGAGGTGACACTATCTGTGGTATTTGGAGGTCTCTAAATCGCTCAACTCTACGTCTTCTCCGCATGGGTCACATTCTGGTATCTTTGGTGACCACAACACTTTCAGAGCCTGAAATATCAGGCAAGATTGTCAAACACAAAGCCCTGTTTTCAGAGTCCTTCAGTGCACTTCTTACCCCAGAAGACTCTGATGTAACAGGAGGTGGAGGACTCGCAATGCTTACACTAAGTGACGTGGATGACAATCTGCACTTTATCCTTATGCTCAGAGGTCTTCGTGGTGGAGAAAGAGATCAGATTCAAATACTTGTGCAAATCTTGCATCAGAACCATGTGATACGGGAGCTTTACGCTAACATCTCTGCACAGGAACAAGACTTTGCAGAGGTGTTGCCAGACCTCTCAAGCCGTGAGATGCAGTGGCTGGCCCAAGGTCAGCTGGAGATTTCAGTGCAGACAGAAGGGAGACGTGGGCAACGCATGTCAGGCATCATCACAGTCAGAAAATCATGTGACACACTGCAGAGTGTGTTGTCTGGTGGTGACACTTTAAATCCCACCAAAACTGGAGCTGTGGGATCTGCAAGCATCACACTGCATGAAAATGGAACCATGGAATATCAGATTCAAATTGCTGGTACCACAAGTGCTGTGACAGCAGTGACACTGGAGACAAAACCTCGCAGAAAAACAAAGAGAAATATACTGCATGATATGACCAAGGACTACCAAGATGGAAGGGTCTGGGGATACTGGATAGATGCTAATGCACGAGACCTACATATGCTGTTGCAAAGTGAGCTCTTCCTTAATGTAGCAACAAAGGATTTCCAGGAAGGGGAACTTAGAGGTCAAATAACCCCTCTGCTATACAGCGGCCTTTGGGCCAGATATGAGCAGCTCCCAGTTCCTCTAGCTGGTCAGTTTGTGTCACCACCCATCAGGACAGGCTCAGCAGGTCACGCATGGGTTTCACTGGATGAGCACTGCCATCTGCATTATCAGATTGTGGTGACTGGTCTGGGTAAGGCAGAGGATGCTGCACTGAATGCTCATCTCCATGGTTTTGCTGAGCTTGGTGAAGTCGGTGAGAGTACCCCTGGGCACAAGAGGTTGTTAAAGGGCTTCTATGGGTCAGAGGCCCAGGGTAGTGTAAAAGACCTTGATCTTGAACTTTTGGGACATCTGAGCCGGGGCACAGCATTTATCCAAGTGAGCACCAAACTGAACCCTCGTGGTGAAATTCGAGGACAAGTGCACATACCTAACAACTGTGAATCTGGAGGAGTCTCTCTAACTCCCGAGGAGCCTGAGTATGAATATGAATTATATGAGGAGGGAAGGCAGCGAGACCCAGAAGATCTTCGGAAAGATCCTAGAGCATGCTTTTTTGAAGGTCAACTAAGAGCCCATGGTTCACGATGGGCTCCAGATTATGACAGGAAATGCTCTGTGTGCAGCTGTCAGAAACGTACCGTGATCTGTGATCCTATTGTGTGCCCACCTCTGAACTGCTCCCAGCCTGTCCATTTGTCAGATCAGTGTTGTCCTGTGTGCGAAGAAAAAAAAGAAATTAGAGAGGTAAAAAAAACCGAGAGAGCTCGCACAGCAAATGAAGGCTGCTTCTTTGATGGAGATCGCTCATGGAAGGCGGCTGGTACACGTTGGCATCCTTTTGTTCCTCCATTTGGTCTAATTAAATGTGCTATTTGCACCTGCAAGGGTTCCACTGGAGAAGTGCATTGTGAGAAGGTGACCTGTCCACGACTTTCCTGTACCAACCCAATTCGTGCTAATCCATCTGATTGCTGCAAACAGTGCCCAGAGGAGCGAAGTCCTTTGGAGCTGGCAGACAGTATGCAGTCAGATGGACCGCGATCATGCAAATTTGGGCGTCACTGGTACCCTAATAATGAGCGCTGGCATCCAACTGTGACACCCTTTGGAGAGATGAAGTGTGTTACATGTGCTTGTGTGGAGGGAGTTACACCGTGTCGGAGACAGGAGTGTACAGGAAATACATGTGGTACTGGTTCAAAGCGGGACAGATGTTGCACCAAGTGCAAAGATGCCAAGCAAGATGAAGATGAAAAGGTGAAATCAGAGGAGACAAGGACTCCGTGGAGTTTCTAGAACGGAGTGCAACTGGGGCAATGGGACTGATTATCAAGGCTCATACAGGCAAGCCCCCAAGCCAAAACAACTGCCAGGACTCATGGATGGTCTGCACAATGTTTTGTCCCACTCTGATGACACTGCTACTGGATTATCTCCTTTTGTTTCATTTGCTGCCATGAAGCAGTGGGATTCTAGAGGCAGCATTTGGAACTAAAATACCTTGCCACCTTGGATTCATCCTTTCAAACACCCAGTCTGTCTTTCTGACAGAAGCAACTCTAAATCCTGCCTAAACAGGACCTGGAGTTTTAACGTCTGATCTGTAGAGTTATGCAACAGGAGCACAGGCACAGCATAGGTAGCTGTGCATATGTAGATATATTGACTAAAAGTGCCCTGTGGCTTTCTGCAGGACGGGAAGAAAAGTACAAGTGACAGACAAAGATTACAGTGTGCTTGCTGGAAAGTCTGTATATATGTCTGCGTGTGTGAATGTGTGAACGCATGATGTTACTTTGAGGGTGTATGAACAGACATATATCATTTCCTATTGTCCAAGCACACTCTTTGAGGAACTTTGTCTTGTATTATTTATGGTATTTTGAGTGGGTGCGGTACCTGTACTAATTAACTATTAATGATGGTCATATTTATTGAACTAAAATAAACTGAAGAAATTTTCCCAGTAATTGTTTTTCTATATTTTATTGGACATGGATAGAGAAGAAGGAAGTGTATATAAGAGGGAACTGGTAGGGGGGATGTCCTGAGTAATGCAAAGTCGTTCATTAATGGGCACATTCTACATTAAATGGCCAATATCCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA	Refseq >NM_001088309\|Xenopus laevis chordin (chrd), mRNA AGAAGTGTCCCCTCCGGACATTGGTACCTGCTGTGAAGAAGAGGCTGGCCCGGGTAGCAGGGAGCGCTCTCTGCACTATTGGAGTGTGTGTGGTGCAAAGTGTGTGTACAGAGCAACAACCCATGTACTGGGAATGTGAGCCAGAGAGCCAGAGACAAGTAGCATAGTAGTCGCTGAGAAGGTGGCAAAGTGACTGGCACAGGCAGACTGAAGGCTCATGGTCCATAGAAGAGTATAGTACAAAGCACAGACATTGTACGCTCACTATACGAGACAGAACGTTTGGAACCACAAAAATGCAGTGTCCCCCCATCCTACTTGTGTGGACCCTGTGGATTATGGCTGTGGATTGCTCTCGCCCAAAGGTTTTCTTGCCCATTCAGCCTGAACAGGAGCCCCTCCAATCCAAGACTCCAGCAGGTTGTACATTTGGTGGGAAATTTTACTCCCTGGAGGATTCATGGCATCCAGATCTTGGGGAACCATTCGGAGTTATGCACTGCGTACTATGCTATTGTGAGCCGCAGCGAAGTCGTCGGGGAAAACCATCTGGTAAAGTCAGCTGCAAAAACATCAAACATGATTGCCCCTCACCCTCCTGTGCTAACCCTATACTGCTCCCATTACATTGCTGCAAGACTTGTCCCAAAGCTCCTCCTCCTCCTATAAAGAAATCAGACTTTGTTTTTGACGGATTTGAGTATTTTCAAGAGAAGGATGATGATCTTTATAATGATCGCTCTTATCTGAGTTCTGATGATGTCGCTGTGGAGGAGAGTCGTTCAGAATATGTGGCACTACTAACAGCACCCAGCCATGTGTGGCCCCCAGTTACCAGTGGAGTAGCCAAGGCTAGATTCAACCTGCAGCGCTCCAATTTGCTCTTCTCAATCACTTATAAATGGATAGACAGACTTTCCAGAATCCGTTTCTCCGATCTTGACGGTTCTGTGCTGTTTGAACACCCAGTGCACAGAATGGGATCCCCACGGGATGACACTATCTGTGGCATTTGGAGGTCCCTTAATCGGTCCACTCTACGTCTTCTCCGAATGGGTCACATTCTTGTATCTCTGGTGACCACAACACTTTCAGAGCCGGAAATATCAGGCAAGATTGTCAAACACAAAGCCCTATTTTCAGAGTCCTTCAGTGCACTTCTTACCCCAGAAGACTCTGATGAAACAGGAGGTGGAGGACTCGCAATGCTAACACTGAGTGATGTGGATGACAATCTGCACTTTATACTTATGCTCAGAGGTCTAAGTGGTGAAGAAGGAGATCAGATTCCAATACTTGTGCAAATCTCACATCAGAACCATGTGATACGGGAGCTATATGCCAACATCTCTGCACAGGAACAAGACTTTGCAGAGGTATTGCCAGACCTTTCCAGTCGAGAAATGCTGTGGCTGGCGCAAGGTCAGCTGGAGATTTCAGTGCAGACAGAAGGGAGACGTCCGCAAAGCATGTCAGGCATAATCACAGTCAGAAAATCATGTGACACTTTGCAGAGTGTGTTATCGGGTGGTGACGCTTTAAATCCCACCAAAACTGGAGCCGTGGGATCTGCAAGCATCACACTTCATGAAAATGGAACTCTGGAATATCAGATTCAAATTGCTGGTACAATGAGTACTGTGACAGCTGTGACACTGGAGACAAAACCTCGCCGAAAAACAAAGAGAAATATTCTGCACGATATGAGCAAGGACTACCATGATGGAAGGGTCTGGGGATATTGGATAGATGCTAATGCCCGAGACCTACATATGCTGTTACAAAGTGAGCTCTTCCTCAATGTAGCGACAAAGGACTTCCAGGAAGGGGAACTCAGGGGACAAATAACCCCTCTGCTATACAGTGGCCTGTGGGCCAGATATGAGAAGCTCCCAGTTCCTCTAGCTGGTCAGTTTGTGTCACCTCCCATCAGGACAGGTTCAGCAGGTCATGCATGGGTTTCACTGGATGAGCACTGCCACCTGCATTATCAGATTGTGGTGACTGGTCTGGGTAAGGCAGAAGATGCTGCACTGAACGCACATCTACATGGTTTTGCTGAGCTTGGAGAGGTCGGTGAGAGCTCTCCTGGACACAAGAGGTTGTTAAAGGGCTTCTATGGGTCAGAGGCACAGGGTAGTGTAAAAGACCTTGACCTTGAACTATTGGGACATCTGAGCCGGGGCACAGCATTTATTCAAGTGAGCACCAAACTGAATCCTCGTGGGGAAATTCGAGGACAGATACACATACCTAACAGCTGTGAATCTGGAGGAGTTTCTCTAACCCCTGAAGAGCCTGAGTATGAATATGAAATATATGAGGAGGGAAGGCAGCGCGACCCTGACGATCTTCGGAAAGACCCCAGAGCATGCTCTTTCGAAGGTCAACTAAGGGCCCATGGTTCACGATGGGCTCCAGACTATGACAGGAAATGCTCTGTGTGCAGCTGTCAGAAGCGTACCGTGATTTGTGATCCTATTGTGTGCCCACCTCTGAACTGCTCCCAGCCTGTCCATTTGCCAGATCAGTGCTGTCCTGTGTGTGAAGAAAAAAAAGAAATGAGAGAGGTGAAAAAACCAGAGAGGGCTCGCACAAGTGAAGGCTGCTTTTTTGATGGAGATCGCTCATGGAAGGCAGCTGGTACACGTTGGCATCCTTTTGTTCCTCCATTTGGTCTAATTAAATGTGCCATTTGCACCTGCAAGGGTTCCACTGGAGAAGTGCACTGTGAGAAGGTGACCTGTCCAAAACTTTCCTGTACCAACCCAATCCGTGCCAATCCTTCTGATTGCTGCAAGCAGTGCCCAGTAGAGGAGCGGAGTCCTATGGAACTGGCAGACAGTATGCAGTCAGATGGAGCAGGATCATGCAGATTTGGGCGTCACTGGTACCCAAATCATGAGCGTTGGCATCCAACTGTGCCACCCTTTGGAGAGATGAAATGTGTTACATGCACTTGTGCGGAGGGCATTACACAGTGTCGGAGACAGGAGTGTACAGGAACTACATGTGGTACTGGTTCAAAGCGGGACAGATGTTGCACCAAGTGCAAAGATGCCAATCAAGATGAAGATGAAAAAGTGAAATCAGACGAGACAAGGACTCCATGGAGTTTTTAGAGAGGAGAGCAACTCGGGCAATGGGACTGATTATCTAGGCTCACAAAAACATGTCCCAAGCTGAGACAACTGCCAGGACTGGATGGTCTGCACAATGTTTTGTTCCACTCTGATAACACTGCTACTGGATTTTACAGTATTTCCATTTGTTTCATTTGCTGCCATGAAGCAGTGGGATTCTGGAGGCAGCATTTGGAACTAAAATACCTTGCCACCTTGGATTCATCCCTTCCAACACCAAGTCAGTCTTTCTGACAGAAGCAACTCTAAATCCTGCCTAAACAGGACCCGGAGTTTTAACGTCTGATCTGTAGAGTTTCGCAACAGGAGCACAGACACAGCATAGGCAGCTGTGCATATGTAGATATACTGACTAAACGTGCCTTGTGGCTCTACAGGACGGGAAGAAAAGTGCAAGAGACAGACAAAGACTACAGTGTTCTTGCTGGAAAGTCTGTATATATGTCTGCGTATGTGAGTGTGTGAACGCATGATTTTACTTTGGGGGTGTATGATCAGACATATATCAGTTCCTCTTGTCCAAGCACACACTTTTGGAAACTTTGTCTTGTATTATTTATGGTATTTTGAGTGGGTGCGGTACCTGTACTAATTAACTATTATTGATGGTCGTATTTATTGAACTAAAATAAACTGAAGACATTTTCCCAGTCA
Protein		Refseq >NP_001136129\|chordin [Xenopus (Silurana) tropicalis] MLCSPILLLWTLWIMAVDCSRPKVFLPIQPEQEPLQSKTPAGCTFGGKFYSLEDSWHPDLGDPFGVMHCVLCYCEPQRSRRGKPSGKVSCKNIKHDCPSPSCSNPVLLSGHCCKTCPKAPPPPIKKSDFVFDGFEYFHGKDDDLYNDRSYLSSDDVTVEENRSEYVALLTAPSHVWPPVTSGVAKARFNLQRSSLLFSITYKWIDRLSRIRFSDLEGSVLFEHPVHRMGSPRGDTICGIWRSLNRSTLRLLRMGHILVSLVTTTLSEPEISGKIVKHKALFSESFSALLTPEDSDVTGGGGLAMLTLSDVDDNLHFILMLRGLRGGERDQIQILVQILHQNHVIRELYANISAQEQDFAEVLPDLSSREMQWLAQGQLEISVQTEGRRGQRMSGIITVRKSCDTLQSVLSGGDTLNPTKTGAVGSASITLHENGTMEYQIQIAGTTSAVTAVTLETKPRRKTKRNILHDMTKDYQDGRVWGYWIDANARDLHMLLQSELFLNVATKDFQEGELRGQITPLLYSGLWARYEQLPVPLAGQFVSPPIRTGSAGHAWVSLDEHCHLHYQIVVTGLGKAEDAALNAHLHGFAELGEVGESTPGHKRLLKGFYGSEAQGSVKDLDLELLGHLSRGTAFIQVSTKLNPRGEIRGQVHIPNNCESGGVSLTPEEPEYEYELYEEGRQRDPEDLRKDPRACFFEGQLRAHGSRWAPDYDRKCSVCSCQKRTVICDPIVCPPLNCSQPVHLSDQCCPVCEEKKEIREVKKTERARTANEGCFFDGDRSWKAAGTRWHPFVPPFGLIKCAICTCKGSTGEVHCEKVTCPRLSCTNPIRANPSDCCKQCPEERSPLELADSMQSDGPRSCKFGRHWYPNNERWHPTVTPFGEMKCVTCACVEGVTPCRRQECTGNTCGTGSKRDRCCTKCKDAKQDEDEKVKSEETRTPWSF	Refseq >NP_001081778\|chordin precursor [Xenopus laevis] MQCPPILLVWTLWIMAVDCSRPKVFLPIQPEQEPLQSKTPAGCTFGGKFYSLEDSWHPDLGEPFGVMHCVLCYCEPQRSRRGKPSGKVSCKNIKHDCPSPSCANPILLPLHCCKTCPKAPPPPIKKSDFVFDGFEYFQEKDDDLYNDRSYLSSDDVAVEESRSEYVALLTAPSHVWPPVTSGVAKARFNLQRSNLLFSITYKWIDRLSRIRFSDLDGSVLFEHPVHRMGSPRDDTICGIWRSLNRSTLRLLRMGHILVSLVTTTLSEPEISGKIVKHKALFSESFSALLTPEDSDETGGGGLAMLTLSDVDDNLHFILMLRGLSGEEGDQIPILVQISHQNHVIRELYANISAQEQDFAEVLPDLSSREMLWLAQGQLEISVQTEGRRPQSMSGIITVRKSCDTLQSVLSGGDALNPTKTGAVGSASITLHENGTLEYQIQIAGTMSTVTAVTLETKPRRKTKRNILHDMSKDYHDGRVWGYWIDANARDLHMLLQSELFLNVATKDFQEGELRGQITPLLYSGLWARYEKLPVPLAGQFVSPPIRTGSAGHAWVSLDEHCHLHYQIVVTGLGKAEDAALNAHLHGFAELGEVGESSPGHKRLLKGFYGSEAQGSVKDLDLELLGHLSRGTAFIQVSTKLNPRGEIRGQIHIPNSCESGGVSLTPEEPEYEYEIYEEGRQRDPDDLRKDPRACSFEGQLRAHGSRWAPDYDRKCSVCSCQKRTVICDPIVCPPLNCSQPVHLPDQCCPVCEEKKEMREVKKPERARTSEGCFFDGDRSWKAAGTRWHPFVPPFGLIKCAICTCKGSTGEVHCEKVTCPKLSCTNPIRANPSDCCKQCPVEERSPMELADSMQSDGAGSCRFGRHWYPNHERWHPTVPPFGEMKCVTCTCAEGITQCRRQECTGTTCGTGSKRDRCCTKCKDANQDEDEKVKSDETRTPWSF UniProtKB

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.26871 [+] Str.5072	Xl.3549
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		172 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	CHRD
mouse		MGI	Chrd	All(4) Targeted, other(3) Targeted, knock Out(1)
zebrafish		ZFIN	chd	27 Lines(s)

Publications
First:		Xenopus chordin: a novel dorsalizing factor activated by organizer-specific homeobox genes. [Cell 1994]
Most recent:		The XenopusTGFBI is required for embryogenesis throughregulation of canonical Wnt signalling. [Dev Biol 2013]
		View All Papers 111 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:
Biological:		multicellular organismal development
Cellular Component:
EC:
KOG:		[WV] von Willebrand factor and related coagulation proteins

Reagents		tropicalis	laevis
Clones		EXRC - 9 clone(s)	EXRC - 3 clone(s)
		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.538.2.A1_at [+] Str.538.2.A2_at Str.5072.1.A1_x_at Str.5072.1.A1_at	Xl.3549.1.S1_at [+] Xl.3549.1.S2_at
Affymetrix 2.0			Xl2.3549.1.S1_a_at

Symbol legend[+]