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Summary Expression Gene Literature (690) GO Terms (11) Nucleotides (630) Proteins (47) Interactants (2500) Wiki
XB-GENEPAGE-480637
Gene Symbol:
chrd.1

Gene Name:
chordin, gene 1

Synonyms:
chd , chordin , X-chordin , chrd , loc108716939 ( Add synonyms , Nomenclature history )

Gene Function:
extracellular BMP antagonist, dorsalizing factor

Protein Function :
Potent dorsalizing factor. Has potent axis-forming activities including the ability to recruit neighboring cells into secondary axes. Regulates cell-cell interactions in the organizing centers of head,...[+]


InterPro :
Chordin , VWF dom , CHRD , PB1 dom [+]

Interactants:
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Diseases: 


External Links:
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Xenbase Gene ID XB-GENE-480638 XB-GENE-17341667 XB-GENE-865395
Gene Symbol chrd.1 chrd.1.L chrd.1.S
Chromosome Chr5 chr5L chr5S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 549011
108716939
398045
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein NCBI Protein  More.. RefSeq Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine chrd.1 chrd.1.L chrd.1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards CHRD OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Chrd MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Chrd Ensembl
zebrafish
ZFIN, AGR chrd ZFIN Ensembl
chicken
GEISHA CHRD Ensembl
fruit fly
worm
Publications
First Xenopus chordin: a novel dorsalizing factor activated by organizer-specific homeobox genes., Cell 1994              
Most Recent Segregation of brain and organizer precursors is differentially regulated by Nodal signaling at blastula stage., Biol Open 2021                  
All View All Papers 187 paper(s) referencing morpholinos 12 paper(s) referencing OMIMs 27 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 5 terms 2 terms 7 terms
PANTHER chrd.1
KEGG Pathways K04657 K04657 K04657
KOG [WV] von Willebrand factor and related coagulation proteins
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks chrd.1
Antibodies Chrd Ab1 Chrd Ab1
Morpholinos (on-target & off-target) chrd.1 MO2 , chrd.1 MO4 , chrd.1 MO7 chrd.1 MO2 , chrd.1 MO4 , chrd.1 MO7 , chrd.1 MO8 chrd.1 MO1 , chrd.1 MO5 , chrd.1 MO3
ORFs chrd.1.S ORF1
Clones EXRC Horizon Source BioScience Horizon Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info