Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (667) GO Terms (8) Nucleotides (613) Proteins (37) Interactants (2438) Wiki
XB-GENEPAGE-480637
Gene Symbol: chrd.1

Gene Name: chordin, gene 1

Synonyms: chd , chordin , X-chordin , chrd , loc108716939 ( Add synonyms , Nomenclature history )

Gene Function: extracellular BMP antagonist, dorsalizing factor

Protein Function :
Potent dorsalizing factor. Has potent axis-forming activities including the ability to recruit neighboring cells into secondary axes. Regulates cell-cell interactions in the organizing centers of head,...[+]


Interactants: Loading ...
1/7
 
Xenbase Gene ID XB-GENE-480638 XB-GENE-17341667 XB-GENE-865395
Gene Symbol chrd.1 chrd.1.L chrd.1.S
Chromosome Chr05 chr5L chr5S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model Gene model
Entrez Gene: 549011
Entrez Gene: 108716939
Entrez Gene: 398045
mRNA RefSeq NCBI Nucleotide RefSeq
Protein RefSeq TrEMBL TrEMBL NCBI Protein RefSeq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine chrd.1 chrd.1.L chrd.1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards CHRD OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Chrd MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR chrd ZFIN Ensembl
chicken
GEISHA CHRD Ensembl
fruit fly
worm
WORMBASE
Publications
First Xenopus chordin: a novel dorsalizing factor activated by organizer-specific homeobox genes., Cell 1994              
Most Recent Lef1 regulates caveolin expression and caveolin dependent endocytosis, a process necessary for Wnt5a/Ror2 signaling during Xenopus gastrulation., Sci Rep 2019                            
All View All Papers 185 paper(s) referencing morpholinos 10 paper(s) referencing OMIMs 23 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 1 terms 0 term 7 terms
PANTHER chrd.1
KEGG Pathways K04657 K04657
KOG [WV] von Willebrand factor and related coagulation proteins
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones EXRC - 8 clone(s)    
Horizon Horizon Horizon
Antibody Chrd Ab1 Chrd Ab1
Morpholino chrd MO1 , chrd MO10 , chrd MO2 , chrd MO3 , chrd MO4 , chrd MO5 , chrd MO6 , chrd MO7 , chrd MO8 , chrd MO9 chrd MO1 , chrd MO10 , chrd MO2 , chrd MO3 , chrd MO4 , chrd MO5 , chrd MO6 , chrd MO7 , chrd MO8 , chrd MO9 chrd MO1 , chrd MO10 , chrd MO2 , chrd MO3 , chrd MO4 , chrd MO5 , chrd MO6 , chrd MO7 , chrd MO8 , chrd MO9
ORF chrd.1.S ORF1
Affymetrix 1.0 Str.538.2.A1_at [+] Xl.3549.1.S1_at [+]
Affymetrix 2.0 Xl2.3549.1.S1_a_at

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
Xenbase: The Xenopus laevis and X. tropicalis resource.
Version: 4.12.2


Major funding for Xenbase is provided by grant P41 HD064556