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Summary Expression Gene Literature (83) GO Terms (15) Nucleotides (101) Proteins (23) Interactants (952) Wiki
XB-GENEPAGE-480716

Gene Symbol: six1

Gene Name: SIX homeobox 1

Synonyms: XSix1 ( Add synonyms , Nomenclature history )

Gene Function: homeodomain transcription factor

Protein Function :
Transcription factor that is involved in the regulation of cell proliferation, apoptosis and embryonic development. Depending on context, functions as transcriptional repressor or activator. Required f...[+]

Interactants: Loading ...
Disease Ontology: branchiootic syndrome [+]

OMIM Diseases: BRANCHIOOTORENAL SYNDROME 1; BOR1 [+]

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Xenbase Gene ID XB-GENE-480717 XB-GENE-480721 XB-GENE-17345620
Gene Symbol six1 six1.L six1.S
Chromosome Chr08 chr8L chr8S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
mRNA RefSeq RefSeq
Protein RefSeq TrEMBL TrEMBL RefSeq TrEMBL Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine six1 six1.L six1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards SIX1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Six1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR ZFIN, AGR six1b six1a ZFIN Ensembl
chicken
GEISHA SIX1 Ensembl
fruit fly
worm
WORMBASE
Publications
First Cell cycle-regulated phosphorylation of the human SIX1 homeodomain protein., J Biol Chem 2000  
Most Recent Prdm12 Directs Nociceptive Sensory Neuron Development by Regulating the Expression of the NGF Receptor TrkA., Cell Rep 2019                    
All View All Papers 15 paper(s) referencing morpholinos 6 paper(s) referencing OMIMs 7 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 15 terms 8 terms 0 term
PANTHER six1
KEGG Pathways K15614 K15614
KOG [K] Transcription factor SIX and related HOX domain proteins
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Dharmacon Dharmacon Dharmacon
Morpholino six1 MO1 , six1 MO2 six1 MO1 , six1 MO2 six1 MO1 , six1 MO2
ORF six1 ORF1
Affymetrix 1.0 Xl.683.1.S1_at
Affymetrix 2.0 Xl2.683.1.S1_at

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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Version: 4.11.4


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