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Summary Expression Gene Literature (61) GO Terms (11) Nucleotides (169) Proteins (39) Interactants (1305) Wiki
XB-GENEPAGE-480799
Gene Symbol:
fzd8

Gene Name:
frizzled class receptor 8

Synonyms:
Xfz8 , Fz-8 , frizzled-8 , frizzled 8 , frizzled8 , fzd8-a , fzd8-b , fz8 ( Add synonyms , Nomenclature history )

Gene Function:
transmembrane receptor in the Wnt signaling pathway

Protein Function :
Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nucl...[+]



Interactants:
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Diseases: 


External Links:
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Xenbase Gene ID XB-GENE-480800 XB-GENE-865411 XB-GENE-6254029
Gene Symbol fzd8 fzd8.L fzd8.S
Chromosome Chr06 chr6L chr6S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100038274
373690
399367
mRNA RefSeq RefSeq RefSeq
Protein RefSeq RefSeq RefSeq Swiss-Prot Swiss-Prot
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining tropicalis laevis.L laevis.S
XenMine fzd8 fzd8.L fzd8.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen tneu087g20      
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards FZD8 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Fzd8 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Fzd8 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR fzd8a fzd8b ZFIN Ensembl
chicken
GEISHA FZD8 Ensembl
fruit fly
worm
Publications
First A role for Xenopus Frizzled 8 in dorsal development., Mech Dev 1998    
Most Recent Assembly of protein complexes restricts diffusion of Wnt3a proteins., Commun Biol 2018  
All View All Papers 7 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 3 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 10 terms 6 terms 0 term
PANTHER fzd8
KEGG Pathways K02375 K02375
KOG [T] Smoothened and related G-protein-coupled receptors
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks fzd8
Morpholinos fzd8 MO1 , fzd8 MO2 , fzd8 MO3 , fzd8 MO4 , fzd8 MO5 fzd8 MO1 , fzd8 MO2 , fzd8 MO3 , fzd8 MO4 , fzd8 MO5 fzd8 MO1 , fzd8 MO2 , fzd8 MO3 , fzd8 MO4 , fzd8 MO5
ORFs fzd8 ORF1
Clones Horizon Source BioScience Horizon Source BioScience EXRC Horizon Source BioScience

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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