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XB-GENEPAGE-
480808
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Gene Symbol: dand5
Gene Name: DAN domain family member 5, BMP antagonist Synonyms: 51-B6 , xCoco , coco , cer2 , crl2 , cerl2 , dante , grem3 , cktsf1b3 , S10-51-B6 , cerl2 , charon Add Xenopus synonyms , Nomenclature history Gene Function: maternal BMP/TGFbeta/Wnt inhibitor Protein Function  :
Plays an important role in regulating the left-right axis by blocking a tgfb1 cascade in the right posterior paraxial mesoderm. Functions as an inhibitor of bmp, tgfb1, nodal, activin and wnt signaling...[+]
Interactants: Loading ... 
Disease Ontology: OMIM Diseases: |
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| Xenbase Gene ID | XB-GENE-480809 | XB-GENE-17340923 | XB-GENE-865412 | ||||
| Gene Symbol | dand5 | dand5.L | dand5.S | ||||
| Chromosome | Chr03 | chr3L | Scaffold20 | ||||
| Molecules | tropicalis | laevis.L | laevis.S | ||||
| Gene |
Genomic sequence
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Genomic sequence
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Genomic sequence
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| CDS |
Gene model
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Entrez Gene
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Entrez Gene
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Entrez Gene
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| mRNA |
Refseq
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Refseq
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| Protein
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Refseq
TrEMBL
Swiss-Prot
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TrEMBL |
Refseq
Swiss-Prot
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| Genomic | tropicalis | laevis.L | laevis.S | ||||
| Genome Browser |
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| Links |
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| Genomic Synteny | Genomicus PANTHER | ||||||
| Expression | tropicalis | laevis.L | laevis.S | ||||
| Ensembl | Ensembl | ||||||
| UniGene | Str.3903 [+] | Xl.51884 | |||||
| RNA-Seq profile | Stage profile: |
Stage profile:
Tissue heatmap:
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| Experimental regulation |
Regulation heatmap:
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| Images | 9 expression image(s) for tropicalis and laevis | ||||||
| Data Mining | tropicalis | laevis.L | laevis.S | ||||
| XenMine | dand5 | dand5.L | dand5.S | ||||
| Phenotype | tropicalis | laevis.L | laevis.S | ||||
| Smith Morpholino Screen | |||||||
| Orthology |
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| zebrafish |
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| fruit fly |
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| Publications | |||||||
| First: |
Xenopus Dan, a member of the Dan gene family of BMP antagonists, is expressed in derivatives of the cranial and trunk neural crest. [Mech Dev 2001]
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| Most recent: | Asymmetric distribution of biomolecules of maternal origin in the Xenopus laevis egg and their impact on the developmental plan. [Sci Rep 2018] | ||||||
| View All Papers 4 paper(s) referencing morpholinos 3 paper(s) referencing OMIMs 8 paper(s) referencing Disease Ontology | |||||||
| Functional Ontologies | tropicalis | laevis.L | laevis.S | ||||
| GO | 7 terms | 1 terms | 6 terms | ||||
| PANTHER | dand5 | ||||||
| KEGG Pathways | |||||||
| KOG | |||||||
| Reagents | tropicalis | laevis.L | laevis.S | ||||
| CRISPR / TALEN | CRISPR tools | CRISPR tools | CRISPR tools | ||||
| Clones | |||||||
| GE Dharmacon | GE Dharmacon | GE Dharmacon | |||||
| Source BioScience | Source BioScience | ||||||
| Antibody | Dand5 Ab1 | ||||||
| Morpholino | dand5 MO1 , dand5 MO2 | dand5 MO1 , dand5 MO2 | dand5 MO1 , dand5 MO2 | ||||
| ORF | dand5.S ORF1 | ||||||
| Affymetrix 1.0 | Str.3903.1.S1_at [+] | Xl.25775.1.A1_at | |||||
| Affymetrix 2.0 | Xl2.51884.2.S2_at [+] | ||||||
Symbol legend[+]
