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Summary Expression Gene Literature (49) GO Terms (11) Nucleotides (154) Proteins (33) Interactants (715) Wiki
XB-GENEPAGE-480808
Gene Symbol:
dand5

Gene Name:
DAN domain family member 5, BMP antagonist

Synonyms:
51-B6 , xCoco , coco , cer2 , crl2 , cerl2 , dante , grem3 , cktsf1b3 , S10-51-B6 , cerl2 , charon ( Add synonyms , Nomenclature history )

Gene Function:
maternal BMP/TGFbeta/Wnt inhibitor

Protein Function :
Plays an important role in regulating the left-right axis by blocking a tgfb1 cascade in the right posterior paraxial mesoderm. Functions as an inhibitor of bmp, tgfb1, nodal, activin and wnt signaling...[+]


InterPro :
Cys knot C , Cerberus , Cystine-knot cytokine , DAN

Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-480809 XB-GENE-17340923 XB-GENE-865412
Gene Symbol dand5 dand5.L dand5.S
Chromosome Chr3 chr3L Scaffold20
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 733727
108711702
594864
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. NCBI Protein TrEMBL RefSeq Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine dand5 dand5.L dand5.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards DAND5 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Dand5 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Dand5 Ensembl
zebrafish
ZFIN, AGR dand5 ZFIN Ensembl
chicken
fruit fly
worm
Publications
First Isolation of two closely related vitellogenin genes, including their flanking regions, from a Xenopus laevis gene library., Proc Natl Acad Sci U S A 1980  
Most Recent Aquatic models of human ciliary diseases., Genesis 2021            
All View All Papers 6 paper(s) referencing morpholinos 4 paper(s) referencing OMIMs 13 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 7 terms 1 terms 6 terms
PANTHER dand5
KEGG Pathways
KOG
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks dand5
Antibodies Dand5 Ab1
Morpholinos (on-target & off-target) dand5 MO2 dand5 MO1 , dand5 MO2 dand5 MO2 , dand5 MO1
ORFs dand5.S ORF1
Clones Horizon Source BioScience Horizon Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info