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Summary Expression Gene Literature (30) GO Terms (11) Nucleotides (138) Proteins (21) Interactants (639) Wiki
XB-GENEPAGE- 480808

Gene Symbol: dand5

Gene Name: DAN domain family member 5, BMP antagonist

Synonyms: 51-B6 , xCoco , coco , cer2 , crl2 , cerl2 , dante , grem3 , cktsf1b3 , S10-51-B6 , cerl2 , charon
Add Xenopus synonyms , Nomenclature history


Gene Function: maternal BMP/TGFbeta/Wnt inhibitor

Protein Function :
Plays an important role in regulating the left-right axis by blocking a tgfb1 cascade in the right posterior paraxial mesoderm. Functions as an inhibitor of bmp, tgfb1, nodal, activin and wnt signaling...[+]


Interactants: Loading ...

Disease Ontology:
  

OMIM Diseases:
  
 

Xenbase Gene ID XB-GENE-480809 XB-GENE-17340923 XB-GENE-865412
Gene Symbol dand5 dand5.L dand5.S
Chromosome Chr03 chr3L Scaffold20
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq TrEMBL Swiss-Prot TrEMBL Refseq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus PANTHER
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.3903 [+] Xl.51884
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 9 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine dand5 dand5.L dand5.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards DAND5 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Dand5 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR dand5 ZFIN Ensembl
chicken
fruit fly
worm
WORMBASE
Publications
First: Xenopus Dan, a member of the Dan gene family of BMP antagonists, is expressed in derivatives of the cranial and trunk neural crest. [Mech Dev 2001]
Most recent: Asymmetric distribution of biomolecules of maternal origin in the Xenopus laevis egg and their impact on the developmental plan. [Sci Rep 2018]
View All Papers 4 paper(s) referencing morpholinos 3 paper(s) referencing OMIMs 8 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 7 terms 1 terms 6 terms
PANTHER dand5
KEGG Pathways
KOG
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Antibody Dand5 Ab1
Morpholino dand5 MO1 , dand5 MO2 dand5 MO1 , dand5 MO2 dand5 MO1 , dand5 MO2
ORF dand5.S ORF1
Affymetrix 1.0 Str.3903.1.S1_at [+] Xl.25775.1.A1_at
Affymetrix 2.0 Xl2.51884.2.S2_at [+]

Symbol legend[+]
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