Transcription factor. Acts early in neural crest formation, functioning redundantly with the other group E Sox factors sox9 and sox10 to induce neural crest progenitors. Regulates the onset of expressi...[+]

Transcription factor. Acts early in neural crest formation, functioning redundantly with the other group E Sox factors sox9 and sox10 to induce neural crest progenitors. Regulates the onset of expression of many neural crest marker genes including sox10, and regulates the development of multiple neural crest derivatives. May be required to regulate neural crest cell migration. [-]