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Summary Expression Gene Literature (35) GO Terms (20) Nucleotides (103) Proteins (45) Interactants (850) Wiki
XB-GENEPAGE-480864
Gene Symbol:
sox8

Gene Name:
SRY-box 8

Synonyms:
( Add synonyms , Nomenclature history )

Gene Function:
HMG-box transcription factor

Protein Function :
Transcription factor. Acts early in neural crest formation, functioning redundantly with the other group E Sox factors sox9 and sox10 to induce neural crest progenitors. Regulates the onset of expressi...[+]


InterPro :
Nucleoside diP kinase , NDK-like dom sf , NDK-like dom , Sox N [+]

Interactants:
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Diseases: 


External Links:
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Xenbase Gene ID XB-GENE-480865 XB-GENE-480869 XB-GENE-17340336
Gene Symbol sox8 sox8.L sox8.S
Chromosome Chr9 chr9_10L chr9_10S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100497725
399214
108703222
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein TrEMBL  More.. RefSeq Swiss-Prot  More.. NCBI Protein TrEMBL
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine sox8 sox8.L sox8.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards SOX8 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Sox8 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Sox8 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR sox8b sox8a ZFIN Ensembl
chicken
GEISHA SOX8 Ensembl
fruit fly
worm
Publications
First Induction of the neural crest and the opportunities of life on the edge., Dev Biol 2004  
Most Recent The neural border: Induction, specification and maturation of the territory that generates neural crest cells., Dev Biol 2018      
All View All Papers 11 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 18 terms 4 terms 4 terms
PANTHER sox8
KEGG Pathways K09270 K09270 K09270
KOG [K] HMG-box transcription factor
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks sox8
Morpholinos (on-target & off-target) sox8 MO1 sox8 MO1 sox8 MO1
Clones Horizon Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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