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Summary Expression Gene Literature (9) GO Terms (21) Nucleotides (69) Proteins (30) Interactants (140) Wiki
XB-GENEPAGE-480892
Gene Symbol:
nr4a2

Gene Name:
nuclear receptor subfamily 4 group A member 2

Synonyms:
NGFI-B , rnr1 , hzf-3 , nurr1 , tinur ( Add synonyms , Nomenclature history )

Gene Function:
hormone receptor

Protein Function :
Transcriptional regulator which may play a role in the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons.


InterPro :
Nuclear hrmn rcpt , Znf NHR/GATA , NURR rcpt , Nuc orph rcpt [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
Parkinson's disease

OMIM:
PARKINSON DISEASE, LATE-ONSET; PD

External Links:
 
Xenbase Gene ID XB-GENE-480893 XB-GENE-6486845 XB-GENE-17335195
Gene Symbol nr4a2 nr4a2.L nr4a2.S
Chromosome Chr9 chr9_10L chr9_10S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100101682
108701333
108702961
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. NCBI Protein NCBI Protein  More.. NCBI Protein NCBI Protein  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine nr4a2 nr4a2.L nr4a2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards NR4A2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Nr4a2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Nr4a2 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR nr4a2b nr4a2a ZFIN Ensembl
chicken
GEISHA NR4A2 Ensembl
fruit fly
worm
Publications
First Cloning and sequencing of a Xenopus homologue of the inducible orphan receptor NGFI-B., Biochim Biophys Acta 1993  
Most Recent Epigenetic homogeneity in histone methylation underlies sperm programming for embryonic transcription., Nat Commun 2020                
All View All Papers 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 21 terms 8 terms 8 terms
PANTHER nr4a2
KEGG Pathways K08558 K08558 K08558
KOG [K] Nuclear receptors of the nerve growth factor-induced protein B type
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks nr4a2
Clones Horizon Source BioScience Horizon Horizon
Plasmids Addgene Addgene

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